4HL1

Crystal Structure of New Delhi Metallo-beta-Lactamase-1, Complexed with Cd and Ampicillin

Summary for 4HL1

• Entry DOI: 10.2210/pdb4hl1/pdb
• Related: 3RKJ 3RKK 3SBL 3SFP 3SRX 4GYQ 4GYU 4H0D 4HKY 4HL2
• Descriptor: Beta-lactamase NDM-1, (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CADMIUM ION, ... (5 entities in total)
• Functional Keywords: structural genomics, psi-biology, midwest center for structural genomics, mcsg, structures of mtb proteins conferring susceptibility to known mtb inhibitors, mtbi, alpha-beta-beta-alpha sandwich, hydrolase, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Klebsiella pneumoniae
• Cellular location: Periplasm (Potential): C7C422
• Total number of polymer chains: 2
• Total formula weight: 52916.04

Authors

Kim, Y.,Tesar, C.,Jedrzejczak, R.,Babnigg, J.,Mire, J.,Sacchettini, J.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) (deposition date: 2012-10-15, release date: 2012-12-12, Last modification date: 2023-09-20)

• Primary citation: Kim, Y.,Tesar, C.,Jedrzejczak, R.,Babnigg, J.,Mire, J.,Sacchettini, J.,Joachimiak, A.; Crystal Structure of New Delhi Metallo-beta-Lactamase-1, Complexed with Cd and Ampicillin; To be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)