4RBS
Crystal Structure of New Delhi Metallo-beta-Lactamase-1 in the Complex with Hydrolyzed Meropenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase NDM-1 | polymer | 243 | 25717.9 | 2 | UniProt (C7C422) Pfam (PF00753) | Klebsiella pneumoniae | NDM-1, Metallo-beta-lactamase NDM-1 |
| 2 | C, D, I, J (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, K (A, B) | (2S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-3-methyl-2H-pyrro le-5-carboxylic acid | non-polymer | 399.5 | 2 | Chemie (0RV) | |||
| 4 | F, L, M, O (A, B) | ACETIC ACID | non-polymer | 60.1 | 4 | Chemie (ACY) | |||
| 5 | G, H, N (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | P, Q (A, B) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A, B: 31 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Ser 28 | - | expression tag |
| Asn 29 | - | expression tag |
| Ala 30 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51435.8 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1577.0 | |
| All* | Total formula weight | 53012.9 |
