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8CGH
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BU of 8cgh by Molmil
Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 3)
Descriptor: TAR DNA-binding protein 43
Authors:Arseni, D, Ryskeldi-Falcon, B.
Deposit date:2023-02-04
Release date:2023-08-02
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
8CG3
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BU of 8cg3 by Molmil
Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1)
Descriptor: TAR DNA-binding protein 43
Authors:Arseni, D, Ryskeldi-Falcon, B.
Deposit date:2023-02-03
Release date:2023-08-02
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
8CGG
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BU of 8cgg by Molmil
Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 2)
Descriptor: TAR DNA-binding protein 43
Authors:Arseni, D, Ryskeldi-Falcon, B.
Deposit date:2023-02-04
Release date:2023-08-02
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
7PY2
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BU of 7py2 by Molmil
Structure of pathological TDP-43 filaments from ALS with FTLD
Descriptor: TAR DNA-binding protein 43
Authors:Arseni, D, Hasegawa, H, Murzin, A.G, Kametani, F, Arai, M, Yoshida, M, Falcon, B.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2022-01-19
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure of pathological TDP-43 filaments from ALS with FTLD.
Nature, 601, 2022
7Q4B
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BU of 7q4b by Molmil
Type I beta-amyloid 42 Filaments from Human Brain
Descriptor: Amyloid-beta precursor protein, UNKNOWN ATOM OR ION
Authors:Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M.
Deposit date:2021-10-30
Release date:2021-11-24
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Cryo-EM structures of amyloid-beta 42 filaments from human brains.
Science, 375, 2022
7Q4M
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BU of 7q4m by Molmil
Type II beta-amyloid 42 Filaments from Human Brain
Descriptor: Amyloid-beta precursor protein, UNKNOWN ATOM OR ION
Authors:Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M.
Deposit date:2021-11-01
Release date:2021-11-24
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures of amyloid-beta 42 filaments from human brains.
Science, 375, 2022
8ONS
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BU of 8ons by Molmil
TAF15 amyloid fold in atypical FTLD - Individual 1
Descriptor: TATA-binding protein-associated factor 2N
Authors:Tetter, S, Ryskeldi-Falcon, B.
Deposit date:2023-04-03
Release date:2023-12-06
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (1.97 Å)
Cite:TAF15 amyloid filaments in frontotemporal lobar degeneration.
Nature, 625, 2024
7QWG
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BU of 7qwg by Molmil
TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVF
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BU of 7qvf by Molmil
TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWM
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BU of 7qwm by Molmil
TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWL
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BU of 7qwl by Molmil
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVC
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BU of 7qvc by Molmil
TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022

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