6NNQ
 
 | | Non-covalent structure of SENP1 in complex with SUMO2 | | Descriptor: | Sentrin-specific protease 1, Small ubiquitin-related modifier 3 | | Authors: | Ambaye, N.D. | | Deposit date: | 2019-01-15 | | Release date: | 2019-05-08 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.621 Å) | | Cite: | Noncovalent structure of SENP1 in complex with SUMO2.
Acta Crystallogr.,Sect.F, 75, 2019
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5EEQ
 | | Grb7 SH2 with the G7-B1 bicyclic peptide inhibitor | | Descriptor: | Bicyclic Peptide Inhibitor, Growth factor receptor-bound protein 7, PHOSPHATE ION | | Authors: | Ambaye, N.D, Watson, G.M, Wilce, M.C.J, Wilce, G.M. | | Deposit date: | 2015-10-23 | | Release date: | 2016-06-15 | | Last modified: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
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4Y1L
 | | Ubc9 Homodimer The Missing Link in Poly-SUMO Chain Formation | | Descriptor: | RWD domain-containing protein 3, SUMO-conjugating enzyme UBC9 | | Authors: | Aileen, Y.A, Ambaye, N.D, Li, Y.J, Vega, R, Bzymek, K, Williams, J.C, Hu, W, Chen, Y. | | Deposit date: | 2015-02-08 | | Release date: | 2015-05-06 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | RWD Domain as an E2 (Ubc9)-Interaction Module.
J.Biol.Chem., 290, 2015
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4WWQ
 | | Apo structure of the Grb7 SH2 domain | | Descriptor: | Growth factor receptor-bound protein 7, MALONIC ACID | | Authors: | Watson, G.M, Ambaye, N.D, Wilce, M.C, Wilce, J.A. | | Deposit date: | 2014-11-12 | | Release date: | 2015-09-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
J.Med.Chem., 58, 2015
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3PQZ
 | | Grb7 SH2 with peptide | | Descriptor: | Growth factor receptor-bound protein 7, cyclic peptide | | Authors: | Wilce, J.A. | | Deposit date: | 2010-11-29 | | Release date: | 2011-07-20 | | Last modified: | 2011-09-21 | | Method: | X-RAY DIFFRACTION (2.413 Å) | | Cite: | Structural basis of binding by cyclic nonphosphorylated Peptide antagonists of grb7 implicated in breast cancer progression
J.Mol.Biol., 412, 2011
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4X6S
 | | Grb7 SH2 domain with phosphotyrosine mimetic inhibitor peptide | | Descriptor: | Growth factor receptor-bound protein 7, Phosphotyrosine mimetic inhibitor peptide G7-TEM1 | | Authors: | Watson, G.M, Panjikar, S, Wilce, M.C, Wilce, J.A. | | Deposit date: | 2014-12-09 | | Release date: | 2015-09-23 | | Last modified: | 2015-10-28 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
J.Med.Chem., 58, 2015
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5D0J
 | | Grb7 SH2 with inhibitor peptide | | Descriptor: | G7-TEdFP peptide, Growth factor receptor-bound protein 7, PHOSPHATE ION | | Authors: | Gunzburg, M.J, Watson, G.M, Wilce, J.A, Wilce, M.C.J. | | Deposit date: | 2015-08-03 | | Release date: | 2016-06-15 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
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5EEL
 | | Grb7 SH2 with bicyclic peptide inhibitor | | Descriptor: | Bicyclic Peptide Inhibitor, FORMIC ACID, Growth factor receptor-bound protein 7, ... | | Authors: | Watson, G.M, Gunzburg, M.J, Wilce, M.C.J, Wilce, J.A. | | Deposit date: | 2015-10-23 | | Release date: | 2016-06-15 | | Last modified: | 2018-12-26 | | Method: | X-RAY DIFFRACTION (2.47 Å) | | Cite: | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
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