4ICG
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![BU of 4icg by Molmil](/molmil-images/mine/4icg) | N-terminal dimerization domain of H-NS in complex with Hha (Salmonella Typhimurium) | Descriptor: | DNA-binding protein H-NS, Hemolysin expression modulating protein (Involved in environmental regulation of virulence factors) | Authors: | Ali, S.S, Whitney, J.C, Stevenson, J, Robinson, H, Howell, P.L, Navarre, W.W. | Deposit date: | 2012-12-10 | Release date: | 2013-03-27 | Last modified: | 2016-05-18 | Method: | X-RAY DIFFRACTION (2.9217 Å) | Cite: | Structural Insights into the Regulation of Foreign Genes in Salmonella by the Hha/H-NS Complex. J.Biol.Chem., 288, 2013
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8UXW
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![BU of 8uxw by Molmil](/molmil-images/mine/8uxw) | Arp2/3 branch junction complex, ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-11 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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8UXX
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![BU of 8uxx by Molmil](/molmil-images/mine/8uxx) | Arp2/3 branch junction complex, BeFx state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-11 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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8UZ0
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![BU of 8uz0 by Molmil](/molmil-images/mine/8uz0) | Straight actin filament from Arp2/3 branch junction sample (ADP) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-14 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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8UZ1
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![BU of 8uz1 by Molmil](/molmil-images/mine/8uz1) | Straight actin filament from Arp2/3 branch junction sample (ADP-BeFx) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-14 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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6XH0
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![BU of 6xh0 by Molmil](/molmil-images/mine/6xh0) | |
6XH3
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![BU of 6xh3 by Molmil](/molmil-images/mine/6xh3) | |
6XH2
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6XH1
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4KWV
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![BU of 4kwv by Molmil](/molmil-images/mine/4kwv) | Crystal Structure of human apo-QPRT | Descriptor: | Nicotinate-nucleotide pyrophosphorylase [carboxylating] | Authors: | Malik, S.S, Patterson, D.N, Ncube, Z, Toth, E.A. | Deposit date: | 2013-05-24 | Release date: | 2013-10-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.797 Å) | Cite: | The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid. Proteins, 82, 2014
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4KWW
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![BU of 4kww by Molmil](/molmil-images/mine/4kww) | The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid | Descriptor: | Nicotinate-nucleotide pyrophosphorylase [carboxylating], PHTHALIC ACID | Authors: | Malik, S.S, Dimeka, P.N, Ncube, Z, Toth, E.A. | Deposit date: | 2013-05-24 | Release date: | 2013-10-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid. Proteins, 82, 2014
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5CYS
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4XEG
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![BU of 4xeg by Molmil](/molmil-images/mine/4xeg) | Structure of the enzyme-product complex resulting from TDG action on a G/hmU mismatch | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | Authors: | Pozharski, E, Malik, S.S, Drohat, A.C. | Deposit date: | 2014-12-23 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. Nucleic Acids Res., 43, 2015
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4Z7B
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![BU of 4z7b by Molmil](/molmil-images/mine/4z7b) | Structure of the enzyme-product complex resulting from TDG action on a GfC mismatch | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | Authors: | Pozharski, E, Malik, S.S, Drohat, A.C. | Deposit date: | 2015-04-07 | Release date: | 2015-09-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. Nucleic Acids Res., 43, 2015
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4Z3A
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4Z7Z
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![BU of 4z7z by Molmil](/molmil-images/mine/4z7z) | Structure of the enzyme-product complex resulting from TDG action on a GT mismatch in the presence of excess base | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | Authors: | Pozharski, E, Malik, S.S, Drohat, A.C. | Deposit date: | 2015-04-08 | Release date: | 2015-09-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. Nucleic Acids Res., 43, 2015
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4Z47
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![BU of 4z47 by Molmil](/molmil-images/mine/4z47) | Structure of the enzyme-product complex resulting from TDG action on a GU mismatch in the presence of excess base | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, DNA, ... | Authors: | Pozharski, E, Malik, S.S, Drohat, A.C. | Deposit date: | 2015-04-01 | Release date: | 2015-09-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. Nucleic Acids Res., 43, 2015
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5JXY
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![BU of 5jxy by Molmil](/molmil-images/mine/5jxy) | Enzyme-substrate complex of TDG catalytic domain bound to a G/U analog | Descriptor: | DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | Authors: | Pidugu, L.S, Pozharski, E, Malik, S.S, Drohat, A.C. | Deposit date: | 2016-05-13 | Release date: | 2016-09-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues. Nucleic Acids Res., 44, 2016
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5FF8
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![BU of 5ff8 by Molmil](/molmil-images/mine/5ff8) | TDG enzyme-product complex | Descriptor: | DNA, G/T mismatch-specific thymine DNA glycosylase | Authors: | Pozharski, E, Malik, S.S, Drohat, A.C. | Deposit date: | 2015-12-18 | Release date: | 2016-09-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues. Nucleic Acids Res., 44, 2016
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5HF7
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![BU of 5hf7 by Molmil](/molmil-images/mine/5hf7) | TDG enzyme-substrate complex | Descriptor: | DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | Authors: | Pozharski, E, Malik, S.S, Drohat, A.C. | Deposit date: | 2016-01-06 | Release date: | 2016-09-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues. Nucleic Acids Res., 44, 2016
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7KJR
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![BU of 7kjr by Molmil](/molmil-images/mine/7kjr) | Cryo-EM structure of SARS-CoV-2 ORF3a | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Apolipoprotein A-I, ORF3a protein | Authors: | Kern, D.M, Hoel, C.M, Kotecha, A, Brohawn, S.G. | Deposit date: | 2020-10-26 | Release date: | 2020-11-18 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.08 Å) | Cite: | Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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6XDC
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6U17
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![BU of 6u17 by Molmil](/molmil-images/mine/6u17) | Human thymine DNA glycosylase bound to DNA with 2'-F-5-carboxyl-dC substrate analog | Descriptor: | ACETATE ION, DNA (28-MER), DNA (30-MER), ... | Authors: | Pidugu, L.S, Pozharski, E, Drohat, A.C. | Deposit date: | 2019-08-15 | Release date: | 2019-11-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase. J.Am.Chem.Soc., 141, 2019
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6U15
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6U16
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![BU of 6u16 by Molmil](/molmil-images/mine/6u16) | Human thymine DNA glycosylase N140A mutant bound to DNA with 5-carboxyl-dC substrate | Descriptor: | 1,2-ETHANEDIOL, DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | Authors: | Pidugu, L.S, Pozharski, E, Drohat, A.C. | Deposit date: | 2019-08-15 | Release date: | 2019-11-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase. J.Am.Chem.Soc., 141, 2019
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