5JXY
Enzyme-substrate complex of TDG catalytic domain bound to a G/U analog
Summary for 5JXY
Entry DOI | 10.2210/pdb5jxy/pdb |
Related | 3UFJ 5HF7 |
Descriptor | G/T mismatch-specific thymine DNA glycosylase, DNA (28-MER), ... (4 entities in total) |
Functional Keywords | protein-dna complex, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q13569 |
Total number of polymer chains | 3 |
Total formula weight | 40302.73 |
Authors | Pidugu, L.S.,Pozharski, E.,Malik, S.S.,Drohat, A.C. (deposition date: 2016-05-13, release date: 2016-09-28, Last modification date: 2023-09-27) |
Primary citation | Coey, C.T.,Malik, S.S.,Pidugu, L.S.,Varney, K.M.,Pozharski, E.,Drohat, A.C. Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues. Nucleic Acids Res., 44:10248-10258, 2016 Cited by PubMed: 27580719DOI: 10.1093/nar/gkw768 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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