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5JXY

Enzyme-substrate complex of TDG catalytic domain bound to a G/U analog

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
G/T mismatch-specific thymine DNA glycosylasepolymer20423070.71UniProt (Q13569)
Pfam (PF03167)
Homo sapiens (Human)Thymine-DNA glycosylase,hTDG
2B
(C)
DNA (28-MER)polymer288646.61synthetic construct
3C
(D)
DNA (28-MER)polymer288585.51synthetic construct
4D, E, F
(A, C, D)
waterwater18.0227Chemie (HOH)
Sequence modifications
A: 111 - 308 (UniProt: Q13569)
PDBExternal DatabaseDetails
Gly 105-expression tag
Ser 106-expression tag
His 107-expression tag
Met 108-expression tag
Ala 109-expression tag
Ser 110-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight40302.7
All*Total formula weight40302.7
*Water molecules are not included.

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PDB entries from 2024-10-30

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