4Z3A

Acetate-free structure of the enzyme-product complex resulting from TDG action on a GU mismatch

Summary for 4Z3A

• Entry DOI: 10.2210/pdb4z3a/pdb
• Related: 4XEG 4Z47 4Z7B 4Z7Z 5CYS
• Descriptor: G/T mismatch-specific thymine DNA glycosylase, DNA (28-MER), ... (4 entities in total)
• Functional Keywords: protein-dna complex, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 40190.67

Authors

Pozharski, E.,Malik, S.S.,Drohat, A.C. (deposition date: 2015-03-31, release date: 2015-09-16, Last modification date: 2023-09-27)

• Primary citation: Malik, S.S.,Coey, C.T.,Varney, K.M.,Pozharski, E.,Drohat, A.C.; Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.; Nucleic Acids Res., 43:9541-9552, 2015; PubMed: 26358812; DOI: 10.1093/nar/gkv890

Experimental method

X-RAY DIFFRACTION (1.72 Å)