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1AG7
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BU of 1ag7 by Molmil
CONOTOXIN GS, NMR, 20 STRUCTURES
Descriptor: CONOTOXIN GS
Authors:Hill, J.M, Alewood, P.F, Craik, D.J.
Deposit date:1997-04-03
Release date:1998-04-08
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry.
Structure, 5, 1997
1AV3
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BU of 1av3 by Molmil
POTASSIUM CHANNEL BLOCKER KAPPA CONOTOXIN PVIIA FROM C. PURPURASCENS, NMR, 20 STRUCTURES
Descriptor: Kappa-conotoxin PVIIA
Authors:Scanlon, M.J, Naranjo, D, Thomas, L, Alewood, P.F, Lewis, R.J, Craik, D.J.
Deposit date:1997-09-24
Release date:1998-10-14
Last modified:2020-12-16
Method:SOLUTION NMR
Cite:Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA.
Structure, 5, 1997
1CNN
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BU of 1cnn by Molmil
OMEGA-CONOTOXIN MVIIC FROM CONUS MAGUS
Descriptor: OMEGA-CONOTOXIN MVIIC
Authors:Nielsen, K.J, Adams, D, Thomas, L, Bond, T, Alewood, P.F, Craik, D.J, Lewis, R.J.
Deposit date:1999-05-20
Release date:2000-05-31
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels.
J.Mol.Biol., 289, 1999
4RUD
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BU of 4rud by Molmil
Crystal structure of a three finger toxin
Descriptor: Three-finger toxin 3b, ZINC ION
Authors:Jobichen, C, Sivaraman, J.
Deposit date:2014-11-18
Release date:2016-05-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors.
Br.J.Pharmacol., 177, 2020
5T90
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BU of 5t90 by Molmil
Structural mechanisms for alpha-conotoxin selectivity at the human alpha3beta4 nicotinic acetylcholine receptor
Descriptor: Acetylcholine-binding protein, LsIA
Authors:Abraham, N, Healy, M, Ragnarsson, L, Brust, A, Alewood, P, Lewis, R.
Deposit date:2016-09-08
Release date:2017-04-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural mechanisms for alpha-conotoxin activity at the human alpha 3 beta 4 nicotinic acetylcholine receptor.
Sci Rep, 7, 2017
7LVN
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BU of 7lvn by Molmil
Solution structure of tarantula toxin omega-Avsp1a
Descriptor: Omega-Avsp1a
Authors:Chin, Y.K.Y, Herzig, V, King, G.F.
Deposit date:2021-02-26
Release date:2022-03-02
Last modified:2023-10-11
Method:SOLUTION NMR
Cite:The Tarantula Toxin omega-Avsp1a Specifically Inhibits Human Ca V 3.1 and Ca V 3.3 via the Extracellular S3-S4 Loop of the Domain 1 Voltage-Sensor.
Biomedicines, 10, 2022
5WLX
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BU of 5wlx by Molmil
Solution structure of kappa-theraphotoxin-Aa1a
Descriptor: Kappa-theraphotoxin-Aa1a
Authors:Chin, Y.K.Y, Ma, L, King, G.F.
Deposit date:2017-07-28
Release date:2018-08-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.
Biochem. Pharmacol., 158, 2018
6AZA
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BU of 6aza by Molmil
NMR structure of sea anemone toxin Kappa-actitoxin-Ate1a
Descriptor: ARG-CYS-LYS-THR-CYS-SER-LYS-GLY-ARG-CYS-ARG-PRO-LYS-PRO-ASN-CYS-GLY-NH2
Authors:Chin, Y.K.-Y, Madio, B, King, G.F, Undheim, E.A.B.
Deposit date:2017-09-10
Release date:2018-09-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold.
Cell. Mol. Life Sci., 75, 2018
6CEI
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BU of 6cei by Molmil
Solution NMR Structure of Conotoxin GXIA from Conus geographus
Descriptor: GXIA
Authors:Armstrong, D.A, Rosengren, K.J.
Deposit date:2018-02-12
Release date:2018-03-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Chemical Synthesis and NMR Solution Structure of Conotoxin GXIA from Conus geographus .
Mar Drugs, 19, 2021
6CEG
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BU of 6ceg by Molmil
Solution NMR structure of the omega conotoxin MoVIB from Conus moncuri
Descriptor: conotoxin MoVIB
Authors:Rosengren, K.J.
Deposit date:2018-02-11
Release date:2018-03-07
Last modified:2020-01-01
Method:SOLUTION NMR
Cite:Novel analgesic omega-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides.
Sci Rep, 8, 2018
5T4R
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BU of 5t4r by Molmil
NMR solution structure of the Nav1.7 selective spider venom-derived peptide Pn3a
Descriptor: Mu-theraphotoxin-Pn3a
Authors:Rosengren, K.J, Armstrong, D.A, Vetter, I.
Deposit date:2016-08-30
Release date:2017-09-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Pharmacological characterisation of the highly Na V 1.7 selective spider venom peptide Pn3a.
Sci Rep, 7, 2017
2BC7
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BU of 2bc7 by Molmil
Solution structure of [Sec2,8]-ImI
Descriptor: Alpha-conotoxin ImI
Authors:Armishaw, C.J.
Deposit date:2005-10-18
Release date:2006-03-14
Last modified:2014-08-06
Method:SOLUTION NMR
Cite:{alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists.
J.Biol.Chem., 281, 2006
2FQC
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BU of 2fqc by Molmil
Solution structure of conotoxin pl14a
Descriptor: Alpha/kappa-conotoxin pl14a
Authors:Craik, D.J, Daly, N.L.
Deposit date:2006-01-18
Release date:2006-07-18
Last modified:2020-06-24
Method:SOLUTION NMR
Cite:A Novel Conotoxin Inhibitor of Kv1.6 Channel and nAChR Subtypes Defines a New Superfamily of Conotoxins
Biochemistry, 45, 2006
1A3P
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BU of 1a3p by Molmil
ROLE OF THE 6-20 DISULFIDE BRIDGE IN THE STRUCTURE AND ACTIVITY OF EPIDERMAL GROWTH FACTOR, NMR, 20 STRUCTURES
Descriptor: EPIDERMAL GROWTH FACTOR
Authors:Barnham, K, Torres, A, Alewood, D, Alewood, P, Domagala, T, Nice, E, Norton, R.
Deposit date:1998-01-22
Release date:1998-07-29
Last modified:2018-03-14
Method:SOLUTION NMR
Cite:Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.
Protein Sci., 7, 1998
1ONT
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BU of 1ont by Molmil
NMDA RECEPTOR ANTAGONIST, CONANTOKIN-T, NMR, 17 STRUCTURES
Descriptor: CONANTOKIN-T
Authors:Skjaerbaek, N, Nielsen, K.J, Lewis, R.J, Alewood, P.F, Craik, D.J.
Deposit date:1996-08-27
Release date:1997-09-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy.
J.Biol.Chem., 272, 1997
1NE5
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BU of 1ne5 by Molmil
Solution Structure of HERG Specific Scorpion Toxin CnErg1
Descriptor: ergtoxin
Authors:Torres, A.M, Paramjit, B, Alewood, P, Kuchel, P.W, Vandenberg, J.I.
Deposit date:2002-12-10
Release date:2003-04-01
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin
FEBS Lett., 539, 2003
2MUB
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BU of 2mub by Molmil
Solution structure of the analgesic sea anemone peptide APETx2
Descriptor: Toxin APETx2
Authors:Mobli, M, King, G.F, Rosengren, K.J, Jensen, J.E.
Deposit date:2014-09-07
Release date:2014-12-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores.
J.Med.Chem., 57, 2014
1G9P
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BU of 1g9p by Molmil
SOLUTION STRUCTURE OF THE INSECTICIDAL CALCIUM CHANNEL BLOCKER OMEGA-ATRACOTOXIN-HV2A
Descriptor: OMEGA-ATRACOTOXIN-HV2A
Authors:Wang, X.-H, King, G.F.
Deposit date:2000-11-27
Release date:2002-02-21
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Discovery and structure of a potent and highly specific blocker of insect calcium channels.
J.Biol.Chem., 276, 2001
1HP3
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BU of 1hp3 by Molmil
C-TERMINAL TRUNCATION OF OMEGA-ATRACOTOXIN-HV2A (CT-HV2A)
Descriptor: OMEGA-ATRACOTOXIN-HV2A
Authors:Wang, X.-H, King, G.F.
Deposit date:2000-12-12
Release date:2002-12-11
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Discovery and structure of a potent and highly specific blocker of insect calcium channels
J.Biol.Chem., 276, 2001
2BC8
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BU of 2bc8 by Molmil
[Sec2,3,8,12]-ImI
Descriptor: Alpha-conotoxin ImI
Authors:Armishaw, C.J.
Deposit date:2005-10-18
Release date:2006-03-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:{alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists.
J.Biol.Chem., 281, 2006
1ONU
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BU of 1onu by Molmil
NMDA RECEPTOR ANTAGONIST, CONANTOKIN-G, NMR, 17 STRUCTURES
Descriptor: CONANTOKIN-G
Authors:Skjaerbaek, N, Nielsen, K.J, Lewis, R.J, Alewood, P.F, Craik, D.J.
Deposit date:1996-08-27
Release date:1997-09-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy.
J.Biol.Chem., 272, 1997
2KRA
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BU of 2kra by Molmil
Solution structure of Bv8
Descriptor: Prokineticin Bv8
Authors:Daly, N.L, Craik, D.J, Mobli, M.
Deposit date:2009-12-14
Release date:2010-08-11
Last modified:2014-04-23
Method:SOLUTION NMR
Cite:Chemical synthesis and structure of the prokineticin Bv8
CHEMBIOCHEM, 11, 2010
2M9L
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BU of 2m9l by Molmil
Solution structure of protoxin-1
Descriptor: Beta-theraphotoxin-Tp1a
Authors:Daly, N.
Deposit date:2013-06-13
Release date:2014-04-30
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain.
Curr.Biol., 24, 2014
2NBC
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BU of 2nbc by Molmil
Resonance assignments and structure determination of poneritoxin, omega-PONTX-Ae1a, from Anochetus emarginatus
Descriptor: poneritoxin
Authors:Chin, Y.K.-Y, Touchard, A, King, G.F.
Deposit date:2016-02-03
Release date:2017-01-11
Method:SOLUTION NMR
Cite:Isolation and characterization of a structurally unique beta-hairpin venom peptide from the predatory ant Anochetus emarginatus.
Biochim.Biophys.Acta, 1860, 2016
2N7F
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BU of 2n7f by Molmil
NMR solution structure of muO-conotoxin MfVIA
Descriptor: muO-conotoxin MfVIA
Authors:Schroeder, C.I, Mobli, M.
Deposit date:2015-09-09
Release date:2016-04-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Development of a mu O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.
J.Biol.Chem., 291, 2016

219869

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