1MXN
 
 | | Solution structure of alpha-conotoxin AuIB | | Descriptor: | alpha-conotoxin AuIB | | Authors: | Dutton, J.L, Bansal, P.S, Hogg, R.C, Adams, D.J, Alewood, P.F, Craik, D.J. | | Deposit date: | 2002-10-02 | | Release date: | 2002-12-30 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity.
J.Biol.Chem., 277, 2002
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1PEN
 | | ALPHA-CONOTOXIN PNI1 | | Descriptor: | ALPHA-CONOTOXIN PNIA | | Authors: | Hu, S.-H, Gehrmann, J, Guddat, L.W, Alewood, P.F, Craik, D.J, Martin, J.L. | | Deposit date: | 1996-01-29 | | Release date: | 1997-04-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus.
Structure, 4, 1996
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1R9I
 | | NMR Solution Structure of PIIIA toxin, NMR, 20 structures | | Descriptor: | Mu-conotoxin PIIIA | | Authors: | Nielsen, K.J, Watson, M, Adams, D.J, Hammarstrom, A.K, Gage, P.W, Hill, J.M, Craik, D.J, Thomas, L, Adams, D, Alewood, P.F, Lewis, R.J. | | Deposit date: | 2003-10-30 | | Release date: | 2003-11-18 | | Last modified: | 2019-12-25 | | Method: | SOLUTION NMR | | Cite: | Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels
J.Biol.Chem., 277, 2002
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4RUD
 | | Crystal structure of a three finger toxin | | Descriptor: | Three-finger toxin 3b, ZINC ION | | Authors: | Jobichen, C, Sivaraman, J. | | Deposit date: | 2014-11-18 | | Release date: | 2016-05-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic ACh receptors.
Br.J.Pharmacol., 177, 2020
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1A3P
 | | ROLE OF THE 6-20 DISULFIDE BRIDGE IN THE STRUCTURE AND ACTIVITY OF EPIDERMAL GROWTH FACTOR, NMR, 20 STRUCTURES | | Descriptor: | EPIDERMAL GROWTH FACTOR | | Authors: | Barnham, K, Torres, A, Alewood, D, Alewood, P, Domagala, T, Nice, E, Norton, R. | | Deposit date: | 1998-01-22 | | Release date: | 1998-07-29 | | Last modified: | 2018-03-14 | | Method: | SOLUTION NMR | | Cite: | Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.
Protein Sci., 7, 1998
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7LVN
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5T90
 | | Structural mechanisms for alpha-conotoxin selectivity at the human alpha3beta4 nicotinic acetylcholine receptor | | Descriptor: | Acetylcholine-binding protein, LsIA | | Authors: | Abraham, N, Healy, M, Ragnarsson, L, Brust, A, Alewood, P, Lewis, R. | | Deposit date: | 2016-09-08 | | Release date: | 2017-04-12 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural mechanisms for alpha-conotoxin activity at the human alpha 3 beta 4 nicotinic acetylcholine receptor.
Sci Rep, 7, 2017
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6AZA
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6CEI
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6CEG
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1AKG
 | | ALPHA-CONOTOXIN PNIB FROM CONUS PENNACEUS | | Descriptor: | ALPHA-CONOTOXIN PNIB | | Authors: | Hu, S.-H, Martin, J.L. | | Deposit date: | 1997-05-18 | | Release date: | 1998-05-20 | | Last modified: | 2015-06-10 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Crystal structure at 1.1 A resolution of alpha-conotoxin PnIB: comparison with alpha-conotoxins PnIA and GI.
Biochemistry, 36, 1997
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2MUB
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5T4R
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5WLX
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2BC8
 | | [Sec2,3,8,12]-ImI | | Descriptor: | Alpha-conotoxin ImI | | Authors: | Armishaw, C.J. | | Deposit date: | 2005-10-18 | | Release date: | 2006-03-14 | | Last modified: | 2014-08-06 | | Method: | SOLUTION NMR | | Cite: | {alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists.
J.Biol.Chem., 281, 2006
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2BC7
 | | Solution structure of [Sec2,8]-ImI | | Descriptor: | Alpha-conotoxin ImI | | Authors: | Armishaw, C.J. | | Deposit date: | 2005-10-18 | | Release date: | 2006-03-14 | | Last modified: | 2014-08-06 | | Method: | SOLUTION NMR | | Cite: | {alpha}-Selenoconotoxins, a New Class of Potent {alpha}7 Neuronal Nicotinic Receptor Antagonists.
J.Biol.Chem., 281, 2006
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1NE5
 | | Solution Structure of HERG Specific Scorpion Toxin CnErg1 | | Descriptor: | ergtoxin | | Authors: | Torres, A.M, Paramjit, B, Alewood, P, Kuchel, P.W, Vandenberg, J.I. | | Deposit date: | 2002-12-10 | | Release date: | 2003-04-01 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin
FEBS Lett., 539, 2003
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2FQC
 | | Solution structure of conotoxin pl14a | | Descriptor: | Alpha/kappa-conotoxin pl14a | | Authors: | Craik, D.J, Daly, N.L. | | Deposit date: | 2006-01-18 | | Release date: | 2006-07-18 | | Last modified: | 2020-06-24 | | Method: | SOLUTION NMR | | Cite: | A Novel Conotoxin Inhibitor of Kv1.6 Channel and nAChR Subtypes Defines a New Superfamily of Conotoxins
Biochemistry, 45, 2006
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2KRA
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1HP3
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1CNL
 | | ALPHA-CONOTOXIN IMI | | Descriptor: | PROTEIN (ALPHA-CONOTOXIN IMI) | | Authors: | Gehrmann, J, Daly, N.L, Craik, D.J. | | Deposit date: | 1999-05-20 | | Release date: | 1999-05-27 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance.
J.Med.Chem., 42, 1999
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2M9L
 | | Solution structure of protoxin-1 | | Descriptor: | Beta-theraphotoxin-Tp1a | | Authors: | Daly, N. | | Deposit date: | 2013-06-13 | | Release date: | 2014-04-30 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1-S4 gating domain.
Curr.Biol., 24, 2014
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2MXM
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2NBC
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2N7F
 | | NMR solution structure of muO-conotoxin MfVIA | | Descriptor: | muO-conotoxin MfVIA | | Authors: | Schroeder, C.I, Mobli, M. | | Deposit date: | 2015-09-09 | | Release date: | 2016-04-06 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Development of a mu O-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.
J.Biol.Chem., 291, 2016
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