1WLF
 
 | | Structure of the N-terminal domain of PEX1 AAA-ATPase: Characterization of a putative adaptor-binding domain | | 分子名称: | Peroxisome biogenesis factor 1, SULFATE ION | | 著者 | Shiozawa, K, Maita, N, Tomii, K, Seto, A, Goda, N, Tochio, H, Akiyama, Y, Shimizu, T, Shirakawa, M, Hiroaki, H. | | 登録日 | 2004-06-25 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of the N-terminal Domain of PEX1 AAA-ATPase: CHARACTERIZATION OF A PUTATIVE ADAPTOR-BINDING DOMAIN
J.Biol.Chem., 279, 2004
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3B44
 | | Crystal structure of GlpG W136A mutant | | 分子名称: | glpG, nonyl beta-D-glucopyranoside | | 著者 | Wang, Y, Maegawa, S, Akiyama, Y, Ha, Y. | | 登録日 | 2007-10-23 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
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3B45
 | | Crystal structure of GlpG at 1.9A resolution | | 分子名称: | glpG, nonyl beta-D-glucopyranoside | | 著者 | Wang, Y, Maegawa, S, Akiyama, Y, Ha, Y. | | 登録日 | 2007-10-23 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
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6A8V
 | | PhoQ sensor domain (D179R mutant): analysis of internal cavity | | 分子名称: | Sensor protein PhoQ | | 著者 | Yoshitani, K, Ishii, E, Taniguchi, K, Sugimoto, H, Shiro, Y, Mori, H, Akiyama, Y, Kato, A, Utsumi, R, Eguchi, Y. | | 登録日 | 2018-07-10 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Identification of an internal cavity in the PhoQ sensor domain for PhoQ activity and SafA-mediated control.
Biosci. Biotechnol. Biochem., 83, 2019
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6A8U
 | | PhoQ sensor domain (wild type): analysis of internal cavity | | 分子名称: | Sensor protein PhoQ | | 著者 | Yoshitani, K, Ishii, E, Taniguchi, K, Sugimoto, H, Shiro, Y, Mori, H, Akiyama, Y, Kato, A, Utsumi, R, Eguchi, Y. | | 登録日 | 2018-07-10 | | 公開日 | 2019-01-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.848 Å) | | 主引用文献 | Identification of an internal cavity in the PhoQ sensor domain for PhoQ activity and SafA-mediated control.
Biosci. Biotechnol. Biochem., 83, 2019
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8WSM
 | | NLRP3 NACHT domain in complex with compound 32 | | 分子名称: | 2-[[2-methyl-5-(trifluoromethyl)phenyl]amino]-~{N}-(1,4-oxazepan-4-ylsulfonyl)-1,3-oxazole-4-carboxamide, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Akai, S, Orita, T, Adachi, T. | | 登録日 | 2023-10-17 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery of Novel NLRP3 Inflammasome Inhibitors Composed of an Oxazole Scaffold Bearing an Acylsulfamide.
Acs Med.Chem.Lett., 14, 2023
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5B1S
 | | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with 2-(2-fluorophenyl)ethanamine | | 分子名称: | 2-(2-fluorophenyl)ethanamine, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, Spermidine synthase, ... | | 著者 | Amano, Y, Tateishi, Y. | | 登録日 | 2015-12-17 | | 公開日 | 2016-12-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease
Sci Rep, 7, 2017
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7W6Y
 | | Crystal structure of Kangiella koreensis RseP orthologue in complex with batimastat in space group P1 | | 分子名称: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, Anti sigma-E protein, RseA, ... | | 著者 | Imaizumi, Y, Takanuki, K, Nogi, T. | | 登録日 | 2021-12-02 | | 公開日 | 2022-09-07 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP.
Sci Adv, 8, 2022
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7W6X
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7W6Z
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7W70
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7W71
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2ZPL
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2ZPM
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3UBB
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5AZV
 | | Crystal structure of hPPARgamma ligand binding domain complexed with 17-oxoDHA | | 分子名称: | (4~{Z},7~{Z},10~{Z},13~{Z},19~{Z})-17-oxidanylidenedocosa-4,7,10,13,19-pentaenoic acid, Peroxisome proliferator-activated receptor gamma | | 著者 | Egawa, D, Itoh, T, Yamamoto, K. | | 登録日 | 2015-10-23 | | 公開日 | 2016-07-06 | | 最終更新日 | 2020-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | 17-OxoDHA Is a PPAR alpha/gamma Dual Covalent Modifier and Agonist
Acs Chem.Biol., 2016
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5AZT
 | | Ternary complex of hPPARalpha ligand binding domain, 17-oxoDHA and a SRC1 peptide | | 分子名称: | (4~{Z},7~{Z},10~{Z},13~{Z},19~{Z})-17-oxidanylidenedocosa-4,7,10,13,19-pentaenoic acid, 15-meric peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor alpha | | 著者 | Egawa, D, Itoh, T, Yamamoto, K. | | 登録日 | 2015-10-23 | | 公開日 | 2016-07-06 | | 最終更新日 | 2020-02-26 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | 17-OxoDHA Is a PPAR alpha/gamma Dual Covalent Modifier and Agonist
Acs Chem.Biol., 2016
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7WI3
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7WI4
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5Y4Q
 | | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with N-(4-methoxyphenyl)quinolin-4-amine | | 分子名称: | 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, N-(4-methoxyphenyl)quinolin-4-amine, Spermidine synthase, ... | | 著者 | Amano, Y, Tateishi, Y. | | 登録日 | 2017-08-04 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro , and X-ray Crystallography.
Acs Omega, 8, 2023
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5Y4P
 | | Crystal structure of Trypanosoma cruzi spermidine synthase in complex with 5-methoxy-2-(5-methyl-4,5-dihydro-1H-imidazol-2-yl)phenol | | 分子名称: | 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, 5-methoxy-2-[(5R)-5-methyl-4,5-dihydro-1H-imidazol-2-yl]phenol, Spermidine synthase, ... | | 著者 | Amano, Y, Tateishi, Y. | | 登録日 | 2017-08-04 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro , and X-ray Crystallography.
Acs Omega, 8, 2023
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6AIT
 | | Crystal structure of E. coli BepA | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-barrel assembly-enhancing protease, ZINC ION | | 著者 | Umar, M.S.M, Tanaka, Y, Kamikubo, H, Tsukazaki, T. | | 登録日 | 2018-08-24 | | 公開日 | 2018-12-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.598 Å) | | 主引用文献 | Structural Basis for the Function of the beta-Barrel Assembly-Enhancing Protease BepA.
J. Mol. Biol., 431, 2019
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3WKL
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3WKM
 | | The periplasmic PDZ tandem fragment of the RseP homologue from Aquifex aeolicus in complex with the Fab fragment | | 分子名称: | MOUSE IGG1-KAPPA FAB (HEAVY CHAIN), MOUSE IGG1-KAPPA FAB (LIGHT CHAIN), Putative zinc metalloprotease aq_1964 | | 著者 | Nogi, T, Tabata, S, Tamura-kawakami, K, Takagi, J. | | 登録日 | 2013-10-28 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A Structure-Based Model of Substrate Discrimination by a Noncanonical PDZ Tandem in the Intramembrane-Cleaving Protease RseP
Structure, 22, 2013
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5XI8
 | | Structure and function of the TPR domain | | 分子名称: | Beta-barrel assembly-enhancing protease | | 著者 | Tanaka, Y, Tsukazaki, T. | | 登録日 | 2017-04-26 | | 公開日 | 2017-10-18 | | 最終更新日 | 2017-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The TPR domain of BepA is required for productive interaction with substrate proteins and the beta-barrel assembly machinery complex.
Mol. Microbiol., 106, 2017
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