3NXQ
 
 | | Angiotensin Converting Enzyme N domain glycsoylation mutant (Ndom389) in complex with RXP407 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, CHLORIDE ION, ... | | 著者 | Anthony, C.S, Corradi, H.R, Schwager, S.L.U, Redelinghuys, P, Georgiadis, D, Dive, V, Acharya, K.R, Sturrock, E.D. | | 登録日 | 2010-07-14 | | 公開日 | 2010-09-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | The N domain of human angiotensin-I-converting enzyme: the role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407.
J.Biol.Chem., 285, 2010
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2BRS
 | | EMBP Heparin complex | | 分子名称: | 2-O-sulfo-beta-L-altropyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, EOSINOPHIL-GRANULE MAJOR BASIC PROTEIN, SULFATE ION | | 著者 | Swaminathan, G.J, Myszka, D.G, Katsamba, P.S, Ohnuki, L.E, Gleich, G.J, Acharya, K.R. | | 登録日 | 2005-05-11 | | 公開日 | 2005-10-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Eosinophil-Granule Major Basic Protein, a C-Type Lectin, Binds Heparin
Biochemistry, 44, 2005
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2C01
 | | Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A | | 分子名称: | ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, NONSECRETORY RIBONUCLEASE | | 著者 | Baker, M.D, Holloway, D.E, Swaminathan, G.J, Acharya, K.R. | | 登録日 | 2005-08-24 | | 公開日 | 2006-01-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.
Biochemistry, 45, 2006
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2C6F
 | | Structure of human somatic angiontensin-I converting enzyme N domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Corradi, H.R, Schwager, S.L.U, Nichinda, A, Sturrock, E.D, Acharya, K.R. | | 登録日 | 2005-11-09 | | 公開日 | 2006-11-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Crystal Structure of the N Domain of Human Somatic Angiotensin I-Converting Enzyme Provides a Structural Basis for Domain-Specific Inhibitor Design.
J.Mol.Biol., 357, 2006
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2BZZ
 | | Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A | | 分子名称: | ACETIC ACID, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, NONSECRETORY RIBONUCLEASE | | 著者 | Baker, M.D, Holloway, D.E, Swaminathan, G.J, Acharya, K.R. | | 登録日 | 2005-08-24 | | 公開日 | 2006-01-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | | 主引用文献 | Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.
Biochemistry, 45, 2006
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2BWK
 | | Murine angiogenin, sulphate complex | | 分子名称: | ANGIOGENIN, SULFATE ION | | 著者 | Holloway, D.E, Chavali, G.B, Hares, M.C, Subramanian, V, Acharya, K.R. | | 登録日 | 2005-07-15 | | 公開日 | 2005-11-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of Murine Angiogenin: Features of the Substrate- and Cell-Binding Regions and Prospects for Inhibitor-Binding Studies.
Acta Crystallogr.,Sect.D, 61, 2005
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2BEX
 | | Crystal structure of Placental Ribonuclease Inhibitor in complex with Human Eosinophil Derived Neurotoxin at 2A resolution | | 分子名称: | ALPHA-KETOMALONIC ACID, GLYCEROL, NONSECRETORY RIBONUCLEASE, ... | | 著者 | Iyer, S, Holloway, D.E, Kumar, K, Shapiro, R, Acharya, K.R. | | 登録日 | 2004-12-01 | | 公開日 | 2005-03-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Molecular Recognition of Human Eosinophil-Derived Neurotoxin (Rnase 2) by Placental Ribonuclease Inhibitor
J.Mol.Biol., 347, 2005
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2C02
 | | Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A | | 分子名称: | ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, NONSECRETORY RIBONUCLEASE | | 著者 | Baker, M.D, Holloway, D.E, Swaminathan, G.J, Acharya, K.R. | | 登録日 | 2005-08-24 | | 公開日 | 2006-01-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.
Biochemistry, 45, 2006
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2BWL
 | | Murine angiogenin, phosphate complex | | 分子名称: | ANGIOGENIN, PHOSPHATE ION | | 著者 | Holloway, D.E, Chavali, G.B, Hares, M.C, Subramanian, V, Acharya, K.R. | | 登録日 | 2005-07-15 | | 公開日 | 2005-11-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Structure of Murine Angiogenin: Features of the Substrate- and Cell-Binding Regions and Prospects for Inhibitor-Binding Studies.
Acta Crystallogr.,Sect.D, 61, 2005
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2C05
 | | Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A | | 分子名称: | ACETIC ACID, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, NONSECRETORY RIBONUCLEASE | | 著者 | Baker, M.D, Holloway, D.E, Swaminathan, G.J, Acharya, K.R. | | 登録日 | 2005-08-25 | | 公開日 | 2006-01-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.
Biochemistry, 45, 2006
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2BOV
 | | Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MONO-ADP-RIBOSYLTRANSFERASE C3, ... | | 著者 | Holbourn, K.P, Sutton, J.M, Evans, H.R, Shone, C.C, Acharya, K.R. | | 登録日 | 2005-04-14 | | 公開日 | 2005-04-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Molecular Recognition of an Adp-Ribosylating Clostridium Botulinum C3 Exoenzyme by Rala Gtpase
Proc.Natl.Acad.Sci.USA, 102, 2005
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2C6N
 | | Structure of human somatic angiontensin-I converting enzyme N domain with lisinopril | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Corradi, H.R, Schwager, S.L.U, Nichinda, A, Sturrock, E.D, Acharya, K.R. | | 登録日 | 2005-11-10 | | 公開日 | 2006-03-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design.
J. Mol. Biol., 357, 2006
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1QHC
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2C7W
 | | Crystal Structure of human vascular endothelial growth factor-B: Identification of amino acids important for angiogeninc activity | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, VASCULAR ENDOTHELIAL GROWTH FACTOR B PRECURSOR | | 著者 | Iyer, S, Scotney, P.D, Nash, A.D, Acharya, K.R. | | 登録日 | 2005-11-29 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding
J.Mol.Biol., 359, 2006
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2CLT
 | | Crystal structure of the active form (full-length) of human fibroblast collagenase. | | 分子名称: | CALCIUM ION, INTERSTITIAL COLLAGENASE, ZINC ION | | 著者 | Iyer, S, Visse, R, Nagase, H, Acharya, K.R. | | 登録日 | 2006-04-29 | | 公開日 | 2006-08-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Crystal Structure of an Active Form of Human Mmp-1.
J.Mol.Biol., 362, 2006
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3SNF
 | | Onconase, atomic resolution crystal structure | | 分子名称: | ACETATE ION, Protein P-30, SULFATE ION | | 著者 | Holloway, D.E, Singh, U.P, Shogen, K, Acharya, K.R. | | 登録日 | 2011-06-29 | | 公開日 | 2011-10-05 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Crystal structure of Onconase at 1.1 angstrom resolution--insights into substrate binding and collective motion.
Febs J., 278, 2011
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2GAL
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5GAL
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2X94
 | | Crystal structure of AnCE-perindoprilat complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ANGIOTENSIN CONVERTING ENZYME, ... | | 著者 | Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R. | | 登録日 | 2010-03-14 | | 公開日 | 2010-06-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs.
J.Mol.Biol., 400, 2010
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2WN5
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2WN4
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2WN7
 | | Structural Basis for Substrate Recognition in the Enzymatic Component of ADP-ribosyltransferase Toxin CDTa from Clostridium difficile | | 分子名称: | ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Sundriyal, A, Roberts, A.K, Shone, C.C, Acharya, K.R. | | 登録日 | 2009-07-07 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
J.Biol.Chem., 284, 2009
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2WK5
 | | Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil | | 分子名称: | GLYCEROL, THYMIDINE PHOSPHORYLASE | | 著者 | Mitsiki, E, Papageorgiou, A.C, Iyer, S, Thiyagarajan, N, Prior, S.H, Sleep, D, Finnis, C, Acharya, K.R. | | 登録日 | 2009-06-05 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Structures of Native Human Thymidine Phosphorylase and in Complex with 5-Iodouracil.
Biochem.Biophys.Res.Commun., 386, 2009
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2WN8
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2X7T
 | | Structures of human carbonic anhydrase II inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors. | | 分子名称: | (9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),2,4-TRIENE-3,17-DIYL DISULFAMATE, CARBONIC ANHYDRASE 2, GLYCEROL, ... | | 著者 | Cozier, G.E, Leese, M.P, Lloyd, M.D, Baker, M.D, Thiyagarajan, N, Acharya, K.R, Potter, B.V.L. | | 登録日 | 2010-03-03 | | 公開日 | 2010-03-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structures of Human Carbonic Anhydrase II/Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Non-Steroidal Inhibitors.
Biochemistry, 49, 2010
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