3NXQ
Angiotensin Converting Enzyme N domain glycsoylation mutant (Ndom389) in complex with RXP407
Summary for 3NXQ
Entry DOI | 10.2210/pdb3nxq/pdb |
Related PRD ID | PRD_001050 |
Descriptor | Angiotensin-converting enzyme, TETRAETHYLENE GLYCOL, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | dicarboxy zinc metallopeptidase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 150625.89 |
Authors | Anthony, C.S.,Corradi, H.R.,Schwager, S.L.U.,Redelinghuys, P.,Georgiadis, D.,Dive, V.,Acharya, K.R.,Sturrock, E.D. (deposition date: 2010-07-14, release date: 2010-09-08, Last modification date: 2020-07-29) |
Primary citation | Anthony, C.S.,Corradi, H.R.,Schwager, S.L.,Redelinghuys, P.,Georgiadis, D.,Dive, V.,Acharya, K.R.,Sturrock, E.D. The N domain of human angiotensin-I-converting enzyme: the role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407. J.Biol.Chem., 285:35685-35693, 2010 Cited by PubMed: 20826823DOI: 10.1074/jbc.M110.167866 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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