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4K7E
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BU of 4k7e by Molmil
Crystal structure of Junin virus nucleoprotein
分子名称: Nucleoprotein
著者Zhang, Y.J, Li, L, Liu, X, Dong, S.S, Wang, W.M, Huo, T, Rao, Z.H, Yang, C.
登録日2013-04-17
公開日2013-08-07
最終更新日2013-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Junin virus nucleoprotein
J.Gen.Virol., 94, 2013
4HBG
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BU of 4hbg by Molmil
Crystal structure of Saccharomyces cerevisiae 3 oxoacyl-[acyl carrier protein]-reductase complexed with NADPH (form2)
分子名称: 3-oxoacyl-[acyl-carrier-protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhang, Y.J, Gao, Y.X, Teng, M.K.
登録日2012-09-27
公開日2013-10-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal structure of yeast mitochondria 3-Oxoacyl-ACP Reductase OAR1
To be Published
8DO5
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BU of 8do5 by Molmil
Crystal structure of NahE in complex with intermediate (R)-4-hydroxy-4-(2-hydroxyphenyl)-2-iminobutanoate
分子名称: (4R)-4-hydroxy-4-(2-hydroxyphenyl)butanoic acid, DIMETHYL SULFOXIDE, Trans-ohydrobenzylidenepyruvate hydratase aldolase
著者LeVieux, J.A, Hardtke, H.A, Zhang, Y.J.
登録日2022-07-12
公開日2022-12-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A mutagenic analysis of NahE, a hydratase-aldolase in the naphthalene degradative pathway.
Arch.Biochem.Biophys., 733, 2023
5C2Y
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BU of 5c2y by Molmil
Crystal structure of the Saccharomyces cerevisiae Rtr1 (regulator of transcription)
分子名称: GLYCEROL, RNA polymerase II subunit B1 CTD phosphatase RTR1, SULFATE ION, ...
著者Yogesha, S.D, Irani, S, Zhang, Y.J.
登録日2015-06-16
公開日2016-05-04
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase.
Sci.Signal., 9, 2016
6DAQ
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BU of 6daq by Molmil
PhdJ bound to substrate intermediate
分子名称: PhdJ
著者Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P.
登録日2018-05-01
公開日2019-04-10
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily.
Biochemistry, 57, 2018
6DAN
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PhdJ WT 2 Angstroms resolution
分子名称: CHLORIDE ION, PhdJ
著者Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P.
登録日2018-05-01
公開日2019-04-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily.
Biochemistry, 57, 2018
6DAO
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BU of 6dao by Molmil
NahE WT selenomethionine
分子名称: Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase
著者Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P.
登録日2018-05-01
公開日2019-05-08
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.939 Å)
主引用文献Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily.
Biochemistry, 57, 2018
6DU3
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BU of 6du3 by Molmil
Structure of Scp1 D96N bound to REST-pS861/4 peptide
分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, REST-pS861
著者Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
登録日2018-06-19
公開日2018-09-26
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
6DU2
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BU of 6du2 by Molmil
Structure of Scp1 D96N bound to REST-pS861/4 peptide
分子名称: MAGNESIUM ION, REST-pS861/4, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2
著者Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
登録日2018-06-19
公開日2018-09-26
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
6VVR
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BU of 6vvr by Molmil
Q0 fused 4-OT wild type symmetric trimer
分子名称: Tautomerase
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2020-02-18
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 59, 2020
6VVM
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R7 fused 4-OT wild type asymmetric trimer
分子名称: 4-oxalocrotonate tautomerase family enzyme
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2020-02-18
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 59, 2020
6VVW
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W0 fused 4-OT wild type symmetric trimer
分子名称: Tautomerase
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2020-02-18
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 59, 2020
6VVN
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F6 fused 4-OT wild type asymmetric trimer
分子名称: 4-oxalocrotonate tautomerase, GLYCEROL
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2020-02-18
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 59, 2020
8T9P
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BU of 8t9p by Molmil
Crystal Structure of YR, a heterohexamer of the 4-oxalocrotonate tautomerase (4-OT) family
分子名称: Tautomerase alpha subunit, Tautomerase beta subunit
著者Moreno, R.Y, Zhang, Y.J.
登録日2023-06-24
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Introduction of Asymmetry in the Fused 4-Oxalocrotonate Tautomerases.
Biochemistry, 62, 2023
8T9O
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BU of 8t9o by Molmil
Crystal structure of CF, a heterohexamer of the 4-oxalocrotonate tautomerase (4-OT) family
分子名称: Tautomerase alpha subunit, Tautomerase beta subunit
著者Moreno, R.Y, Zhang, Y.J.
登録日2023-06-24
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Introduction of Asymmetry in the Fused 4-Oxalocrotonate Tautomerases.
Biochemistry, 62, 2023
8T9Q
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BU of 8t9q by Molmil
Crystal structure of fused YR, an asymmetric 4-OT trimer
分子名称: Tautomerase
著者Moreno, R.Y, Zhang, Y.J.
登録日2023-06-24
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Introduction of Asymmetry in the Fused 4-Oxalocrotonate Tautomerases.
Biochemistry, 62, 2023
8UKE
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BU of 8uke by Molmil
Crystal Structure of Norbelladine O-methyltransferase variant in complex with SAH
分子名称: CALCIUM ION, Norbelladine 4'-O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Kim, W, Zhang, Y.J.
登録日2023-10-12
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme.
Nat Commun, 15, 2024
6OGM
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BU of 6ogm by Molmil
Crystal structure of apo unFused 4-OT
分子名称: 4-oxalocrotonate tautomerase, GLYCEROL
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2019-04-03
公開日2020-02-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.865 Å)
主引用文献Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 58, 2019
5UIF
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BU of 5uif by Molmil
Crystal Structure of Native Ps01740
分子名称: Ps01740
著者LeVieux, J, Baas, B.J, Zhang, Y.J, Whitman, C.P.
登録日2017-01-13
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp. UW4: A potential step between subgroups in the tautomerase superfamily.
Arch. Biochem. Biophys., 636, 2017
5UNQ
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BU of 5unq by Molmil
Crystal Structure of Pt0534 Inactivated by 2-Oxo-3-pentynoate
分子名称: Putative tautomerase
著者LeVieux, J, Baas, B.J, Zhang, Y.J, Whitman, C.P.
登録日2017-01-31
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.976 Å)
主引用文献A global view of structure-function relationships in the tautomerase superfamily.
J. Biol. Chem., 293, 2018
5V43
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BU of 5v43 by Molmil
Engineered human IgG Fc domain aglyco801
分子名称: Ig gamma-1 chain C region
著者Yan, W, Marshall, N, Zhang, Y.J.
登録日2017-03-08
公開日2017-06-21
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
5V4E
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BU of 5v4e by Molmil
Engineered human IgG Fc domain glyco801 (Fc801)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, W, Marshall, N, Zhang, Y.J.
登録日2017-03-09
公開日2017-06-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.216 Å)
主引用文献IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
7S3V
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Structure of HsKYNase_66, an evolved variant of human kynureninase with greatly increased activity towards kynurenine
分子名称: Kynureninase
著者Burkholder, N.T, Zhang, Y.J.
登録日2021-09-08
公開日2022-12-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.249 Å)
主引用文献Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme.
Nat Catal, 5, 2022
7TVK
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Structural, Kinetic, and Mechanistic Analysis of the Wild-Type and Inactivated Malonate Semialdehyde Decarboxylase: A Structural Basis for the Decarboxylase and Hydratase Activities
分子名称: Malonate Semialdehyde Decarboxylase
著者Yang, W.J, Zhang, Y.J.
登録日2022-02-05
公開日2022-12-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Kinetic, Inhibition, and Structural Characterization of a Malonate Semialdehyde Decarboxylase-like Protein from Calothrix sp. PCC 6303: A Gateway to the non-Pro1 Tautomerase Superfamily Members.
Biochemistry, 2022
7Y3Z
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Structure of a novel carboxylesterase FEH from Acinetobacter sp. DL-2
分子名称: Fenoxaprop-p-ethyl hydrolase
著者Huang, Y, Liu, W.D, Zhang, Y.J, Duan, Y.J, Lu, M.L.
登録日2022-06-13
公開日2023-07-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a novel carboxylesterase FEH from Acinetobacter sp. DL-2
To Be Published

 

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