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5VOZ
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BU of 5voz by Molmil
Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 3)
Descriptor: Uncharacterized protein, V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, ...
Authors:Zhao, J.
Deposit date:2017-05-03
Release date:2017-06-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
5VOY
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BU of 5voy by Molmil
Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 2)
Descriptor: V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Zhao, J.
Deposit date:2017-05-03
Release date:2017-06-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
8WO0
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BU of 8wo0 by Molmil
CryoEM structure of ZIKV rsNS1 filament
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1
Authors:Chew, B.L.A, Luo, D.
Deposit date:2023-10-06
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
8WN8
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BU of 8wn8 by Molmil
CryoEM structure of ZIKV rsNS1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1
Authors:Chew, B.L.A, Luo, D.
Deposit date:2023-10-05
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
8WNP
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BU of 8wnp by Molmil
ZIKV rsNS1 in complex with Fab AA12 and anti-fab nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2023-10-06
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
8WO4
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BU of 8wo4 by Molmil
ZIKV rsNS1 in complex with Fab EB9 and anti-fab nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2023-10-06
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
8WNU
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BU of 8wnu by Molmil
ZIKV rsNS1 in complex with Fab GB5 and anti-fab nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-fab nanobody, Non-structural protein 1, ...
Authors:Chew, B.L.A, Luo, D.
Deposit date:2023-10-06
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of Zika virus NS1 multimerization and human antibody recognition
Npj Viruses, 2, 2024
2ZBG
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BU of 2zbg by Molmil
Calcium pump crystal structure with bound AlF4 and TG in the absence of calcium
Descriptor: MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ...
Authors:Toyoshima, C, Ogawa, H, Norimatsu, Y.
Deposit date:2007-10-20
Release date:2007-12-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump
Proc.Natl.Acad.Sci.Usa, 104, 2007
2ZBE
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BU of 2zbe by Molmil
Calcium pump crystal structure with bound BeF3 in the absence of calcium and TG
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Authors:Toyoshima, C, Ogawa, H, Norimatsu, Y.
Deposit date:2007-10-20
Release date:2007-12-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump
Proc.Natl.Acad.Sci.Usa, 104, 2007
2ZBF
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BU of 2zbf by Molmil
Calcium pump crystal structure with bound BeF3 and TG in the absence of calcium
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ...
Authors:Toyoshima, C, Ogawa, H, Norimatsu, Y.
Deposit date:2007-10-20
Release date:2007-12-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump
Proc.Natl.Acad.Sci.Usa, 104, 2007
8DS8
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BU of 8ds8 by Molmil
Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide
Descriptor: Histone H3.1, Trinucleotide repeat-containing gene 18 protein
Authors:Song, J.K, Lu, J.W.
Deposit date:2022-07-21
Release date:2023-08-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons.
Nature, 623, 2023
8ESM
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BU of 8esm by Molmil
Human triacylglycerol synthesizing enzyme DGAT1 in complex with T863 inhibitor
Descriptor: Diacylglycerol O-acyltransferase 1, {(1r,4r)-4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl}acetic acid
Authors:Sui, X, Kun, W, Walther, T, Farese, R, Liao, M.
Deposit date:2022-10-14
Release date:2023-06-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
Nat Commun, 14, 2023
8ETM
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BU of 8etm by Molmil
Human triacylglycerol synthesizing enzyme DGAT1 in complex with DGAT1IN1 inhibitor
Descriptor: Diacylglycerol O-acyltransferase 1, [(1S,4r)-4-{4-[(4S)-2-({[4-(trifluoromethoxy)phenyl]methyl}carbamoyl)imidazo[1,2-a]pyridin-6-yl]phenyl}cyclohexyl]acetic acid
Authors:Sui, X, Kun, W, Walther, T, Farese, R, Liao, M.
Deposit date:2022-10-17
Release date:2023-06-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
Nat Commun, 14, 2023
3KDU
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BU of 3kdu by Molmil
Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-((4-methylphenoxy)carbonyl)glycine
Descriptor: N-(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzyl)-N-[(4-methylphenoxy)carbonyl]glycine, Peroxisome proliferator-activated receptor alpha
Authors:Muckelbauer, J.K.
Deposit date:2009-10-23
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453).
J.Med.Chem., 53, 2010
3KDT
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BU of 3kdt by Molmil
Crystal structure of peroxisome proliferator-activatedeceptor alpha (PPARalpha) complex with N-3-((2-(4-Chlorophenyl)-5-methyl-1,3-oxazol-4-yl)methoxy)benzyl)-N-(methoxycarbonyl)glycine
Descriptor: N-(3-{[2-(4-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methoxy}benzyl)-N-(methoxycarbonyl)glycine, Peroxisome proliferator-activated receptor alpha
Authors:Muckelbauer, J.K.
Deposit date:2009-10-23
Release date:2010-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of an oxybenzylglycine based peroxisome proliferator activated receptor alpha selective agonist 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid (BMS-687453).
J.Med.Chem., 53, 2010
6L8R
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BU of 6l8r by Molmil
membrane-bound PD-L1-CD
Descriptor: Programmed cell death 1 ligand 1
Authors:Maorong, W, Cao, Y, Bin, W, Bo, O.
Deposit date:2019-11-07
Release date:2020-11-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain.
Nat Commun, 12, 2021
7L0Y
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BU of 7l0y by Molmil
Human Bocavirus 1 (pH 2.6)
Descriptor: VP2
Authors:Luo, M, Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2020-12-13
Release date:2021-01-27
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:pH-Induced Conformational Changes of Human Bocavirus Capsids.
J.Virol., 95, 2021
7L0X
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BU of 7l0x by Molmil
Human Bocavirus 2 (pH 2.6)
Descriptor: VP2
Authors:Luo, M, Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2020-12-13
Release date:2021-01-27
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:pH-Induced Conformational Changes of Human Bocavirus Capsids.
J.Virol., 95, 2021
7L0U
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BU of 7l0u by Molmil
Human Bocavirus 2 (pH 5.5)
Descriptor: VP2
Authors:Luo, M, Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2020-12-13
Release date:2021-01-27
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:pH-Induced Conformational Changes of Human Bocavirus Capsids.
J.Virol., 95, 2021
7L0W
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BU of 7l0w by Molmil
Human Bocavirus 1 (pH 5.5)
Descriptor: VP2
Authors:Luo, M, Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2020-12-13
Release date:2021-01-27
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:pH-Induced Conformational Changes of Human Bocavirus Capsids.
J.Virol., 95, 2021
7L0V
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BU of 7l0v by Molmil
Human Bocavirus 2 (pH 7.4)
Descriptor: VP2
Authors:Luo, M, Mietzsch, M, Agbandje-McKenna, M.
Deposit date:2020-12-13
Release date:2021-01-27
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:pH-Induced Conformational Changes of Human Bocavirus Capsids.
J.Virol., 95, 2021
2ZBD
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BU of 2zbd by Molmil
Crystal Structure of the SR Calcium Pump with Bound Aluminium Fluoride, ADP and Calcium
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Toyoshima, C, Nomura, H, Tsuda, T, Ogawa, H, Norimatsu, Y.
Deposit date:2007-10-20
Release date:2007-11-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues
Nature, 432, 2004
3FDR
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BU of 3fdr by Molmil
Crystal structure of TDRD2
Descriptor: Tudor and KH domain-containing protein
Authors:Amaya, M.F, Adams, M.A, Guo, Y, Li, Y, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2008-11-26
Release date:2009-01-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi
Proc.Natl.Acad.Sci.USA, 106, 2009
7MDY
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BU of 7mdy by Molmil
LolCDE nucleotide-bound
Descriptor: ADP ORTHOVANADATE, Lipo-releasing system transmembrane protein lolC, Lipoprotein transporter subunit LolE, ...
Authors:Sharma, S, Liao, M.
Deposit date:2021-04-06
Release date:2021-08-11
Last modified:2021-08-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
Nat Commun, 12, 2021
7MDX
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BU of 7mdx by Molmil
LolCDE nucleotide-free
Descriptor: (2R)-2-(tridecanoyloxy)propyl hexadecanoate, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolC, ...
Authors:Sharma, S, Liao, M.
Deposit date:2021-04-06
Release date:2021-08-11
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins
Nat Commun, 12, 2021

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数据于2024-05-22公开中

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