6MCK
 
 | | p97 D1D2 with CB5083 bound | | 分子名称: | 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, Transitional endoplasmic reticulum ATPase | | 著者 | Xia, D, Tang, W.K. | | 登録日 | 2018-08-31 | | 公開日 | 2019-01-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.77 Å) | | 主引用文献 | Structural Basis of p97 Inhibition by the Site-Selective Anticancer Compound CB-5083.
Mol. Pharmacol., 95, 2019
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6NIN
 | | Rhodobacter sphaeroides bc1 with STIGMATELLIN A | | 分子名称: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Cytochrome b, Cytochrome c1, ... | | 著者 | Xia, D, Zhou, F, Esser, L. | | 登録日 | 2018-12-31 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Crystal structure of bacterial cytochromebc1in complex with azoxystrobin reveals a conformational switch of the Rieske iron-sulfur protein subunit.
J.Biol.Chem., 294, 2019
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6NHG
 | | Rhodobacter sphaeroides Mitochondrial respiratory chain complex | | 分子名称: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, ... | | 著者 | Xia, D, Zhou, F, Esser, L. | | 登録日 | 2018-12-21 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of bacterial cytochromebc1in complex with azoxystrobin reveals a conformational switch of the Rieske iron-sulfur protein subunit.
J.Biol.Chem., 294, 2019
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6NHH
 | | Rhodobacter sphaeroides bc1 with azoxystrobin | | 分子名称: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Cytochrome b, Cytochrome c1, ... | | 著者 | Xia, D, Zhou, F, Yu, C.A. | | 登録日 | 2018-12-21 | | 公開日 | 2019-06-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of bacterial cytochromebc1in complex with azoxystrobin reveals a conformational switch of the Rieske iron-sulfur protein subunit.
J.Biol.Chem., 294, 2019
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4KO8
 | | Structure of p97 N-D1 R155H mutant in complex with ATPgS | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Xia, D, Tang, W.K. | | 登録日 | 2013-05-11 | | 公開日 | 2013-11-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
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4KOD
 | | Structure of p97 N-D1 R155H mutant in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | 著者 | Xia, D, Tang, W.K. | | 登録日 | 2013-05-11 | | 公開日 | 2013-11-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
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4F33
 | | Crystal Structure of therapeutic antibody MORAb-009 | | 分子名称: | MORAb-009 FAB heavy chain, MORAb-009 FAB light chain, TETRAETHYLENE GLYCOL | | 著者 | Xia, D, Ma, J, Tang, W.K, Esser, L. | | 登録日 | 2012-05-08 | | 公開日 | 2012-07-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
J.Biol.Chem., 287, 2012
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4KLN
 | | Structure of p97 N-D1 A232E mutant in complex with ATPgS | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | | 著者 | Xia, D, Tang, W.K. | | 登録日 | 2013-05-07 | | 公開日 | 2013-11-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
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4F3F
 | | Crystal Structure of Msln7-64 MORAb-009 FAB complex | | 分子名称: | MORAb-009 Fab heavy chain, MORAb-009 Fab light chain, Mesothelin | | 著者 | Xia, D, Pastan, I, Ma, J, Tang, W.K, Esser, L. | | 登録日 | 2012-05-09 | | 公開日 | 2012-07-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
J.Biol.Chem., 287, 2012
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8CX3
 | | Crystal structure of full-length mesothelin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | 著者 | Zhan, J, Esser, L, Xia, D. | | 登録日 | 2022-05-19 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.609 Å) | | 主引用文献 | Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies.
Cancer Res Commun, 3, 2023
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1SQP
 | | Crystal Structure Analysis of Bovine Bc1 with Myxothiazol | | 分子名称: | (2Z,6E)-7-{2'-[(2E,4E)-1,6-DIMETHYLHEPTA-2,4-DIENYL]-2,4'-BI-1,3-THIAZOL-4-YL}-3,5-DIMETHOXY-4-METHYLHEPTA-2,6-DIENAMID E, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | | 著者 | Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. | | 登録日 | 2004-03-19 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.
J.Mol.Biol., 341, 2004
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1SQQ
 | | Crystal Structure Analysis of Bovine Bc1 with Methoxy Acrylate Stilbene (MOAS) | | 分子名称: | Cytochrome b, Cytochrome c1, heme protein, ... | | 著者 | Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. | | 登録日 | 2004-03-19 | | 公開日 | 2005-10-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.
J.Mol.Biol., 341, 2004
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1SQB
 | | Crystal Structure Analysis of Bovine Bc1 with Azoxystrobin | | 分子名称: | Cytochrome b, Cytochrome c1, heme protein, ... | | 著者 | Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. | | 登録日 | 2004-03-18 | | 公開日 | 2004-09-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex
J.Mol.Biol., 341, 2004
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1SQV
 | | Crystal Structure Analysis of Bovine Bc1 with UHDBT | | 分子名称: | 6-HYDROXY-5-UNDECYL-1,3-BENZOTHIAZOLE-4,7-DIONE, Cytochrome b, Cytochrome c1, ... | | 著者 | Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. | | 登録日 | 2004-03-19 | | 公開日 | 2005-09-06 | | 最終更新日 | 2021-03-03 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.
J.Mol.Biol., 341, 2004
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1SQX
 | | Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A | | 分子名称: | Cytochrome b, Cytochrome c1, heme protein, ... | | 著者 | Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. | | 登録日 | 2004-03-21 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.
J.Mol.Biol., 341, 2004
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7U9J
 | | Crystal structure of Mesothelin-207 fragment | | 分子名称: | GLYCEROL, Isoform 3 of Mesothelin, SULFATE ION | | 著者 | Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D. | | 登録日 | 2022-03-10 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies.
Cancer Res Commun, 3, 2023
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7UED
 | | Crystal structure of full length mesothelin bound with MORAb-009 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Isoform 4 of Mesothelin, ... | | 著者 | Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D. | | 登録日 | 2022-03-21 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies.
Cancer Res Commun, 3, 2023
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2BPA
 | | ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS | | 分子名称: | DNA (5'-D(*AP*AP*AP*AP*C)-3'), PROTEIN (SUBUNIT OF BACTERIOPHAGE PHIX174) | | 著者 | McKenna, R, Xia, D, Willingmann, P, Ilag, L.L, Krishnaswamy, S, Rossmann, M.G, Olson, N.H, Baker, T.S, Incardona, N.L. | | 登録日 | 1991-12-03 | | 公開日 | 1991-12-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Atomic structure of single-stranded DNA bacteriophage phi X174 and its functional implications.
Nature, 355, 1992
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2HB0
 | | Crystal Structure of CfaE, the Adhesive Subunit of CFA/I Fimbria of Enterotoxigenic Escherichia coli | | 分子名称: | CFA/I fimbrial subunit E, DI(HYDROXYETHYL)ETHER, MALONATE ION | | 著者 | Li, Y.F, Xia, D, Poole, S, Rasulova, F, Savarino, S.J. | | 登録日 | 2006-06-13 | | 公開日 | 2007-06-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A receptor-binding site as revealed by the crystal structure of CfaE, the colonization factor antigen I fimbrial adhesin of enterotoxigenic Escherichia coli.
J.Biol.Chem., 282, 2007
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1FEP
 | | FERRIC ENTEROBACTIN RECEPTOR | | 分子名称: | FERRIC ENTEROBACTIN RECEPTOR | | 著者 | Buchanan, S.K, Smith, B.S, Ventatramani, L, Xia, D, Esser, L, Palnitkar, M, Chakraborty, R, Van Der Helm, D, Deisenhofer, J. | | 登録日 | 1998-11-24 | | 公開日 | 1999-01-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the outer membrane active transporter FepA from Escherichia coli.
Nat.Struct.Biol., 6, 1999
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5KIW
 | | p97 ND1-L198W in complex with VIMP | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ... | | 著者 | Tang, W.K, Xia, D. | | 登録日 | 2016-06-17 | | 公開日 | 2018-03-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Structural basis for nucleotide-modulated p97 association with the ER membrane.
Cell Discov, 3, 2017
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5KIY
 | | p97 ND1-A232E in complex with VIMP | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ... | | 著者 | Tang, W.K, Xia, D. | | 登録日 | 2016-06-17 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structural basis for nucleotide-modulated p97 association with the ER membrane.
Cell Discov, 3, 2017
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5KIU
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6UKS
 | | ATPgammaS bound mBcs1 | | 分子名称: | MAGNESIUM ION, Mitochondrial chaperone BCS1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Tang, W.K, Borgnia, M.J, Hsu, A.L, Xia, D. | | 登録日 | 2019-10-05 | | 公開日 | 2020-02-05 | | 最終更新日 | 2020-02-26 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020
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6U1Y
 | | bcs1 AAA domain | | 分子名称: | MAGNESIUM ION, Mitochondrial chaperone BCS1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Tang, W.K, Xia, D. | | 登録日 | 2019-08-17 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020
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