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3HJ2
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BU of 3hj2 by Molmil
Crystal structure of covalent dimer of HNP1
Descriptor: HUMAN NEUTROPHIL PEPTIDE 1
Authors:Lubkowski, J, Pazgier, M, Lu, W.
Deposit date:2009-05-20
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:What Dictates the Multifaced Functions of the Human alpha-Defensin HNP1?
To be Published
3HJD
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BU of 3hjd by Molmil
X-ray structure of monomeric variant of HNP1
Descriptor: Human neutrophil peptide 1
Authors:Lubkowski, J, Pazgier, M, Lu, W.
Deposit date:2009-05-21
Release date:2009-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:What Dictates the Multifaced Functions of the Human alpha-Defensin HNP?
To be Published
7XUN
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BU of 7xun by Molmil
Structure of ATP7B C983S/C985S/D1027A mutant
Descriptor: Copper-transporting ATPase 2
Authors:Yang, G, Xu, L, Guo, J, Wu, Z.
Deposit date:2022-05-19
Release date:2023-04-26
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
7XUO
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BU of 7xuo by Molmil
Structure of ATP7B C983S/C985S/D1027A mutant with cisplatin in presence of ATOX1
Descriptor: Copper-transporting ATPase 2, PLATINUM (II) ION
Authors:Yang, G, Xu, L, Chang, S, Guo, J, Wu, Z.
Deposit date:2022-05-19
Release date:2023-04-26
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
7XUK
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BU of 7xuk by Molmil
Structure of ATP7B C983S/C985S/D1027A mutant in presence of ATOX1
Descriptor: Copper-transporting ATPase 2
Authors:Yang, G, Xu, L, Guo, J, Wu, Z.
Deposit date:2022-05-18
Release date:2023-04-26
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
7XUM
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BU of 7xum by Molmil
Structure of ATP7B C983S/C985S/D1027A mutant with Cu+ in presence of ATOX1
Descriptor: COPPER (II) ION, Copper-transporting ATPase 2
Authors:Yang, G, Xu, L, Chang, S, Guo, J, Wu, Z.
Deposit date:2022-05-19
Release date:2023-05-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
5XGV
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BU of 5xgv by Molmil
The structure of Diels-Alderase PyrE3 in the biosynthetic pathway of pyrroindomycins
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PyrE3
Authors:Pan, L, Gong, Y, Guo, Y.
Deposit date:2017-04-18
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural Insights into a Flavin-Dependent [4 + 2] Cyclase that Catalyzes trans-Decalin Formation in Pyrroindomycin Biosynthesis.
Cell Chem Biol, 25, 2018
3SLU
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BU of 3slu by Molmil
Crystal structure of NMB0315
Descriptor: M23 peptidase domain protein, NICKEL (II) ION
Authors:Shen, Y, Wang, X, Yang, X, Xu, H.
Deposit date:2011-06-26
Release date:2012-02-01
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structure of outer membrane protein NMB0315 from Neisseria meningitidis.
Plos One, 6, 2011
3STO
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BU of 3sto by Molmil
Serpin from the trematode Schistosoma Haematobium
Descriptor: Serine protease inhibitor
Authors:Granzin, J, Weiergraeber, O.H, Lee, X, Blanton, R.E.
Deposit date:2011-07-11
Release date:2012-05-30
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain.
Acta Crystallogr.,Sect.D, 68, 2012
5EAK
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BU of 5eak by Molmil
Optimization of Microtubule Affinity Regulating Kinase (MARK) Inhibitors with Improved Physical Properties
Descriptor: N-[(1S,2R)-2-aminocyclohexyl]-4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl]thiophene-2-carboxamide, Serine/threonine-protein kinase MARK2
Authors:Su, H.P.
Deposit date:2015-10-16
Release date:2016-02-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties.
Bioorg.Med.Chem.Lett., 26, 2016
8GJK
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BU of 8gjk by Molmil
Multi-drug efflux pump RE-CmeB bound with ampicillin
Descriptor: (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Efflux pump membrane transporter
Authors:Zhang, Z.
Deposit date:2023-03-16
Release date:2023-05-31
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
8GJL
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BU of 8gjl by Molmil
multi-drug efflux pump RE-CmeB bound with Ciprofloxacin
Descriptor: 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, Efflux pump membrane transporter
Authors:Zhang, Z.
Deposit date:2023-03-16
Release date:2023-05-31
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
8GJJ
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BU of 8gjj by Molmil
Multi-drug efflux pump RE-CmeB Apo form
Descriptor: Efflux pump membrane transporter
Authors:Zhang, Z.
Deposit date:2023-03-15
Release date:2023-05-31
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
8GK4
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BU of 8gk4 by Molmil
Multi-drug efflux pump RE-CmeB bound with Chloramphenicol
Descriptor: CHLORAMPHENICOL, Efflux pump membrane transporter
Authors:Zhang, Z.
Deposit date:2023-03-17
Release date:2023-05-31
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
8GK0
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BU of 8gk0 by Molmil
Multi-drug efflux pump RE-CmeB bound with Erythromycin
Descriptor: ERYTHROMYCIN A, Efflux pump membrane transporter
Authors:Zhang, Z.
Deposit date:2023-03-16
Release date:2023-06-07
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Cryo-Electron Microscopy Structures of a Campylobacter Multidrug Efflux Pump Reveal a Novel Mechanism of Drug Recognition and Resistance.
Microbiol Spectr, 11, 2023
8GK7
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BU of 8gk7 by Molmil
MsbA bound to cerastecin C
Descriptor: 2-[(4-butylbenzene-1-sulfonyl)amino]-5-[(3-{4-[(4-butylbenzene-1-sulfonyl)amino]-3-carboxyanilino}-3-oxopropyl)carbamoyl]benzoic acid, Lipid A export ATP-binding/permease protein MsbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Chen, Y, Klein, D.
Deposit date:2023-03-17
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii
Nat Microbiol, 2024
8IAZ
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BU of 8iaz by Molmil
Cryo-EM structure of the ISFba1 TnpB-reRNA-dsDNA complex
Descriptor: DNA (5'-D(P*AP*CP*AP*TP*GP*GP*AP*CP*CP*AP*TP*CP*AP*GP*CP*TP*CP*CP*TP*AP*AP*TP*GP*G)-3'), DNA (5'-D(P*CP*CP*AP*TP*TP*AP*GP*GP*AP*GP*CP*TP*GP*AP*TP*G)-3'), RNA (207-MER), ...
Authors:Yin, M, Zhou, F, Zhu, Y, Huang, Z.
Deposit date:2023-02-09
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Discovery and structural mechanism of DNA endonucleases guided by RAGATH-18-derived RNAs.
Cell Res., 2024
6N4W
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BU of 6n4w by Molmil
Tetragonal thermolysin (with 50% xylose) cryocooled in a nitrogen gas stream to 100 K
Descriptor: CALCIUM ION, Thermolysin, ZINC ION, ...
Authors:Juers, D.H, Harrison, K, Wu, B.
Deposit date:2018-11-20
Release date:2019-10-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A comparison of gas stream cooling and plunge cooling of macromolecular crystals.
J.Appl.Crystallogr., 52, 2019
6N4Z
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BU of 6n4z by Molmil
Tetragonal thermolysin (with 50% xylose) plunge cooled in liquid nitrogen to 77 K
Descriptor: CALCIUM ION, Thermolysin, ZINC ION, ...
Authors:Juers, D.H, Harrison, K, Wu, B.
Deposit date:2018-11-20
Release date:2019-10-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A comparison of gas stream cooling and plunge cooling of macromolecular crystals.
J.Appl.Crystallogr., 52, 2019
4PLN
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BU of 4pln by Molmil
Crystal Structure of Chicken Netrin-1 (LN-LE3) complexed with mouse Neogenin (FN4-5)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neogenin, ...
Authors:Xu, K, Nikolov, D.B.
Deposit date:2014-05-18
Release date:2014-06-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
Science, 344, 2014
8HMV
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BU of 8hmv by Molmil
Structure of GPR21-Gs complex
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Wong, T.S, Gao, W.
Deposit date:2022-12-05
Release date:2023-03-01
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Cryo-EM structure of orphan G protein-coupled receptor GPR21.
MedComm (2020), 4, 2023
4PLO
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BU of 4plo by Molmil
Crystal Structure of chicken Netrin-1 (LN-LE3) in complex with mouse DCC (FN4-5)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Netrin receptor DCC, ...
Authors:Xu, K, Nikolov, D.B.
Deposit date:2014-05-18
Release date:2014-06-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
Science, 344, 2014
4PLM
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BU of 4plm by Molmil
Crystal Structure of Chicken Netrin-1 (LN-LE3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Xu, K, Nikolov, D.B.
Deposit date:2014-05-18
Release date:2014-06-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Neural migration. Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism.
Science, 344, 2014
8IJA
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BU of 8ija by Molmil
Cryo-EM structure of human HCAR2-Gi complex with niacin
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Pan, X, Fang, Y.
Deposit date:2023-02-26
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2.
Cell Discov, 9, 2023
8IJD
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BU of 8ijd by Molmil
Cryo-EM structure of human HCAR2-Gi complex with MK-6892
Descriptor: 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Pan, X, Fang, Y.
Deposit date:2023-02-27
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structural insights into ligand recognition and selectivity of the human hydroxycarboxylic acid receptor HCAR2.
Cell Discov, 9, 2023

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