5UOJ
 
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5VTA
 | | Co-Crystal Structure of DPPIV with a Chemibody Inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]piperazin-1-yl}-N-(22-oxo-3,6,9,12,15,18-hexaoxa-21-azatricosan-1-yl)acetamide, ... | | 著者 | Wang, Z, Johnstone, S, Cheng, A. | | 登録日 | 2017-05-16 | | 公開日 | 2018-05-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-guided Discovery of Dual-recognition Chemibodies.
Sci Rep, 8, 2018
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3O33
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3O34
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3O37
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3OQ1
 | | Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor | | 分子名称: | 3-(2-fluoroethyl)-4-({4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl}sulfonyl)benzonitrile, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, Z, Sudom, A, Walker, N.P. | | 登録日 | 2010-09-02 | | 公開日 | 2011-07-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The synthesis and SAR of novel diarylsulfone 11beta-HSD1 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
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3PDJ
 | | Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor | | 分子名称: | Corticosteroid 11-beta-dehydrogenase isozyme 1, N-[trans-4-(3-amino-3-oxopropyl)-4-phenylcyclohexyl]-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Wang, Z, Sudom, A, Walker, N.P. | | 登録日 | 2010-10-22 | | 公開日 | 2011-10-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Synthesis and Optimization of Novel 4,4-Disubstituted Cyclohexylbenzamide Derivatives as Potent 11beta-HSD1 Inhibitors
Bioorg.Med.Chem.Lett., 21, 2011
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3U5O
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3U5M
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6L6V
 | | SPO1 Gp44 N-terminal region (1-55) | | 分子名称: | E3 protein | | 著者 | Liu, B, Wang, Z. | | 登録日 | 2019-10-29 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Bacteriophage DNA Mimic Protein Employs a Non-specific Strategy to Inhibit the Bacterial RNA Polymerase.
Front Microbiol, 12, 2021
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5EJC
 | | Crystal structural of the TSC1-TBC1D7 complex | | 分子名称: | Hamartin, TBC1 domain family member 7 | | 著者 | Wang, Z, Qin, J, Gong, W, Xu, W. | | 登録日 | 2015-11-01 | | 公開日 | 2016-03-02 | | 最終更新日 | 2019-11-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7).
J.Biol.Chem., 291, 2016
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7EBK
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2LYO
 | | CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN 90% ACETONITRILE-WATER | | 分子名称: | ACETONITRILE, LYSOZYME | | 著者 | Huang, Q, Wang, Z, Zhu, G, Qian, M, Shao, M, Jia, Y, Tang, Y. | | 登録日 | 1998-03-06 | | 公開日 | 1998-05-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | X-ray studies on cross-linked lysozyme crystals in acetonitrile-water mixture.
Biochim.Biophys.Acta, 1384, 1998
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4LYO
 | | CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN NEAT ACETONITRILE, THEN BACK-SOAKED IN WATER | | 分子名称: | LYSOZYME | | 著者 | Huang, Q, Wang, Z, Zhu, G, Qian, M, Shao, M, Jia, Y, Tang, Y. | | 登録日 | 1998-03-11 | | 公開日 | 1998-05-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | X-ray studies on cross-linked lysozyme crystals in acetonitrile-water mixture.
Biochim.Biophys.Acta, 1384, 1998
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8H3J
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8H3I
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4QPL
 | | Crystal structure of RNF146(RING-WWE)/UbcH5a/iso-ADPr complex | | 分子名称: | 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate), E3 ubiquitin-protein ligase RNF146, Ubiquitin-conjugating enzyme E2 D1, ... | | 著者 | Wang, Z, DaRosa, P.A, Klevit, R.E, Xu, W. | | 登録日 | 2014-06-23 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.
Nature, 517, 2015
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7EBJ
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7WKH
 | | the grass carp IFNa | | 分子名称: | Interferon | | 著者 | Zou, J, WANG, J, Wang, Z. | | 登録日 | 2022-01-09 | | 公開日 | 2022-02-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structural and Functional Analyses of Type I IFNa Shed Light Into Its Interaction With Multiple Receptors in Fish.
Front Immunol, 13, 2022
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6N4N
 | | Crystal structure of the designed protein DNCR2/danoprevir/NS3a complex | | 分子名称: | (2R,6S,12Z,13aS,14aR,16aS)-6-[(tert-butoxycarbonyl)amino]-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxo-1,2,3,5,6,7,8 ,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoro-2H-isoindole-2-carboxylate, NS3 protease, Rosetta-designed danoprevir/NS3a complex reader 2, ... | | 著者 | Wang, Z, Foight, G.W, Baker, D, Maly, D.J. | | 登録日 | 2018-11-19 | | 公開日 | 2019-09-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Multi-input chemical control of protein dimerization for programming graded cellular responses.
Nat.Biotechnol., 37, 2019
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8H7A
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8J8Q
 | | Structure of the four-component Paf1 complex from Saccharomyces eubayanus | | 分子名称: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | | 著者 | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | | 登録日 | 2023-05-02 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-06-14 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus .
Int J Mol Sci, 24, 2023
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8J8P
 | | Structure of the four-component Paf1 complex from Saccharomyces eubayanus | | 分子名称: | CDC73-like protein, CTR9-like protein, PAF1-like protein, ... | | 著者 | Wang, Z, Qin, Y, Zhou, Y, Cao, Y. | | 登録日 | 2023-05-02 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-06-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Basis of the Transcriptional Elongation Factor Paf1 Core Complex from Saccharomyces eubayanus .
Int J Mol Sci, 24, 2023
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5XFN
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5XFR
 | | Ternary complex of MTF2, DNA and histone | | 分子名称: | DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), Metal-response element-binding transcription factor 2, Peptide from Histone H3.1, ... | | 著者 | Wang, Z, Li, H. | | 登録日 | 2017-04-11 | | 公開日 | 2017-09-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Polycomb-like proteins link the PRC2 complex to CpG islands
Nature, 549, 2017
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