7MOJ
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7MOM
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7OHA
| nucleosome with TBP and TFIIA bound at SHL +2 | Descriptor: | DNA (122-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Wang, H, Cramer, P. | Deposit date: | 2021-05-09 | Release date: | 2021-07-28 | Last modified: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures and implications of TBP-nucleosome complexes. Proc.Natl.Acad.Sci.USA, 118, 2021
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7OH9
| Nucleosome with TBP and TFIIA bound at SHL -6 | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Wang, H, Cramer, P. | Deposit date: | 2021-05-09 | Release date: | 2021-07-28 | Last modified: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures and implications of TBP-nucleosome complexes. Proc.Natl.Acad.Sci.USA, 118, 2021
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7OHB
| TBP-nucleosome complex | Descriptor: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Wang, H, Cramer, P. | Deposit date: | 2021-05-10 | Release date: | 2021-07-28 | Last modified: | 2021-08-04 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures and implications of TBP-nucleosome complexes. Proc.Natl.Acad.Sci.USA, 118, 2021
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7OHC
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7OS7
| Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant | Descriptor: | 30S ribosomal protein S6,30S ribosomal protein S6 | Authors: | Wang, H, Logan, D.T, Oliveberg, M. | Deposit date: | 2021-06-08 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant To Be Published
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4ZYO
| Crystal Structure of Human Integral Membrane Stearoyl-CoA Desaturase with Substrate | Descriptor: | Acyl-CoA desaturase, DODECYL-BETA-D-MALTOSIDE, STEAROYL-COENZYME A, ... | Authors: | Wang, H, Klein, M.G, Lane, W, Snell, G, Levin, I, Li, K, Zou, H, Sang, B.-C. | Deposit date: | 2015-05-21 | Release date: | 2015-06-17 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Crystal structure of human stearoyl-coenzyme A desaturase in complex with substrate. Nat.Struct.Mol.Biol., 22, 2015
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3K3E
| Crystal structure of the PDE9A catalytic domain in complex with (R)-BAY73-6691 | Descriptor: | 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | Authors: | Wang, H, Luo, X, Ye, M, Hou, J, Robinson, H, Ke, H. | Deposit date: | 2009-10-02 | Release date: | 2010-02-16 | Last modified: | 2013-11-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Insight into Binding of Phosphodiesterase-9A Selective Inhibitors by Crystal Structures and Mutagenesis J.Med.Chem., 53, 2010
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3K3H
| Crystal structure of the PDE9A catalytic domain in complex with (S)-BAY73-6691 | Descriptor: | 1-(2-chlorophenyl)-6-[(2S)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | Authors: | Wang, H, Luo, X, Ye, M, Hou, J, Robinson, H, Ke, H. | Deposit date: | 2009-10-02 | Release date: | 2010-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insight into Binding of Phosphodiesterase-9A Selective Inhibitors by Crystal Structures and Mutagenesis J.Med.Chem., 53, 2010
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1WWI
| Crystal structure of ttk003001566 from Thermus Thermophilus HB8 | Descriptor: | hypothetical protein TTHA1479 | Authors: | Wang, H, Murayama, K, Terada, T, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-01-05 | Release date: | 2005-07-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structure of ttk003001566 from Thermus Thermophilus HB8 TO BE PUBLISHED
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6HBA
| Crystal Structure of the small subunit-like domain 1 of CcmM from Synechococcus elongatus (strain PCC 7942), thiol-oxidized form | Descriptor: | Carbon dioxide concentrating mechanism protein CcmM | Authors: | Wang, H, Yan, X, Aigner, H, Bracher, A, Nguyen, N.D, Hee, W.Y, Long, B.M, Price, G.D, Hartl, F.U, Hayer-Hartl, M. | Deposit date: | 2018-08-10 | Release date: | 2018-12-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Rubisco condensate formation by CcmM in beta-carboxysome biogenesis. Nature, 566, 2019
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4ED5
| Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA | Descriptor: | 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 5'-R(*A*UP*UP*UP*UP*UP*AP*UP*UP*UP*U)-3', ... | Authors: | Wang, H, Zeng, F, Liu, Q, Niu, L, Teng, M, Li, X. | Deposit date: | 2012-03-27 | Release date: | 2012-05-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding. Acta Crystallogr.,Sect.D, 69, 2013
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2CSL
| Crystal structure of TTHA0137 from Thermus Thermophilus HB8 | Descriptor: | protein translation initiation inhibitor | Authors: | Wang, H, Murayama, K, Terada, T, Chen, L, Jin, Z, Chrzas, J, Liu, Z.J, Wang, B.C, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-22 | Release date: | 2005-11-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of TTHA0137 from Thermus Thermophilus HB8 To be Published
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2DY1
| Crystal structure of EF-G-2 from Thermus thermophilus | Descriptor: | Elongation factor G, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | Authors: | Wang, H, Takemoto, C, Murayama, K, Terada, T, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-09-04 | Release date: | 2007-09-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of EF-G-2 from Thermus thermophilus To be Published
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1BPR
| NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, MINIMIZED AVERAGE STRUCTURE | Descriptor: | DNAK | Authors: | Wang, H, Kurochkin, A.V, Pang, Y, Hu, W, Flynn, G.C, Zuiderweg, E.R.P. | Deposit date: | 1998-08-11 | Release date: | 1999-03-02 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction. Biochemistry, 37, 1998
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1FBN
| CRYSTAL STRUCTURE OF A FIBRILLARIN HOMOLOGUE FROM METHANOCOCCUS JANNASCHII, A HYPERTHERMOPHILE, AT 1.6 A | Descriptor: | MJ FIBRILLARIN HOMOLOGUE | Authors: | Wang, H, Boisvert, D, Kim, K.K, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 1999-04-25 | Release date: | 2000-04-26 | Last modified: | 2014-11-26 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution. EMBO J., 19, 2000
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1RMV
| RIBGRASS MOSAIC VIRUS, FIBER DIFFRACTION | Descriptor: | RIBGRASS MOSAIC VIRUS COAT PROTEIN, RIBGRASS MOSAIC VIRUS RNA | Authors: | Wang, H, Stubbs, G. | Deposit date: | 1997-02-11 | Release date: | 1997-05-15 | Last modified: | 2023-08-09 | Method: | FIBER DIFFRACTION (2.9 Å) | Cite: | Molecular dynamics in refinement against fiber diffraction data. Acta Crystallogr.,Sect.A, 49, 1993
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1YNS
| Crystal Structure Of Human Enolase-phosphatase E1 and its complex with a substrate analog | Descriptor: | 2-OXOHEPTYLPHOSPHONIC ACID, E-1 enzyme, MAGNESIUM ION | Authors: | Wang, H, Pang, H, Bartlam, M, Rao, Z. | Deposit date: | 2005-01-25 | Release date: | 2005-05-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of human e1 enzyme and its complex with a substrate analog reveals the mechanism of its phosphatase/enolase J.Mol.Biol., 348, 2005
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1ZS9
| Crystal structure of human enolase-phosphatase E1 | Descriptor: | E-1 ENZYME, MAGNESIUM ION | Authors: | Wang, H, Pang, H, Bartlam, M, Rao, Z. | Deposit date: | 2005-05-23 | Release date: | 2005-06-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Human E1 Enzyme and its Complex with a Substrate Analog Reveals the Mechanism of its Phosphatase/Enolase J.Mol.Biol., 348, 2005
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3ECN
| Crystal structure of PDE8A catalytic domain in complex with IBMX | Descriptor: | 3-ISOBUTYL-1-METHYLXANTHINE, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, MAGNESIUM ION, ... | Authors: | Wang, H, Yan, Z, Yang, S, Cai, J, Robinson, H, Ke, H. | Deposit date: | 2008-09-01 | Release date: | 2008-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity Biochemistry, 47, 2008
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3KH8
| Crystal structure of MaoC-like dehydratase from Phytophthora Capsici | Descriptor: | MaoC-like dehydratase | Authors: | Wang, H, Zhang, K, Guo, J, Zhou, Q, Zheng, X, Sun, F, Pang, H, Zhang, X. | Deposit date: | 2009-10-30 | Release date: | 2010-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of MaoC-like dehydratase from Phytophthora Capsici To be Published
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3ECM
| Crystal structure of the unliganded PDE8A catalytic domain | Descriptor: | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, MAGNESIUM ION, ZINC ION | Authors: | Wang, H, Yan, Z, Yang, S, Cai, J, Robinson, H, Ke, H. | Deposit date: | 2008-09-01 | Release date: | 2008-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity Biochemistry, 47, 2008
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3KUZ
| Crystal structure of the ubiquitin like domain of PLXNC1 | Descriptor: | Plexin-C1, UNKNOWN ATOM OR ION | Authors: | Wang, H, Li, B, Tempel, W, Tong, Y, Guan, X, Zhong, N, Crombet, L, MacKenzie, F, Buck, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-28 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the ubiquitin like domain of PLXNC1 to be published
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3NGO
| Crystal structure of the human CNOT6L nuclease domain in complex with poly(A) DNA | Descriptor: | 5'-D(*AP*AP*AP*A)-3', CCR4-NOT transcription complex subunit 6-like, MAGNESIUM ION | Authors: | Wang, H, Morita, M, Yang, W, Bartlam, M, Yamamoto, T, Rao, Z. | Deposit date: | 2010-06-12 | Release date: | 2010-07-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. Embo J., 2010
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