5WPL
 
 | | KRas G12V, bound to GppNHp and miniprotein 225-11 | | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Lee, S.-J, Shim, S.Y, McGee, J.H, Verdine, G.L. | | 登録日 | 2017-08-05 | | 公開日 | 2018-01-03 | | 最終更新日 | 2018-03-14 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
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5WHE
 | | KRas G12V/D38P, bound to GppNHp and miniprotein 225-11 | | 分子名称: | CALCIUM ION, GTPase KRas, MAGNESIUM ION, ... | | 著者 | Shim, S.Y, McGee, J.H, Lee, S.-J, Verdine, G.L. | | 登録日 | 2017-07-16 | | 公開日 | 2018-01-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
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3U6C
 | | MutM set 1 ApGo | | 分子名称: | DNA (5'-D(*GP*GP*TP*AP*GP*AP*TP*CP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*CP*AP*(8OG)P*GP*AP*(TX)P*CP*TP*AP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | 著者 | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | 登録日 | 2011-10-12 | | 公開日 | 2012-04-25 | | 最終更新日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM.
J.Biol.Chem., 287, 2012
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3U6P
 | | MutM set 1 GpG | | 分子名称: | DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*TP*CP*CP*CP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*GP*GP*GP*AP*(08Q)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | 著者 | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | 登録日 | 2011-10-12 | | 公開日 | 2012-04-25 | | 最終更新日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM.
J.Biol.Chem., 287, 2012
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3U6O
 | | MutM set 1 ApG | | 分子名称: | DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*TP*CP*CP*TP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*AP*GP*GP*AP*(08Q)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | 著者 | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | 登録日 | 2011-10-12 | | 公開日 | 2012-04-25 | | 最終更新日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM.
J.Biol.Chem., 287, 2012
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3U6L
 | | MutM set 2 CpGo | | 分子名称: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*GP*TP*(CX2)P*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | 著者 | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | 登録日 | 2011-10-12 | | 公開日 | 2012-04-25 | | 最終更新日 | 2017-01-11 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM.
J.Biol.Chem., 287, 2012
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3U6M
 | | Structural effects of sequence context on lesion recognition by MutM | | 分子名称: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*AP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*TP*(8OG)P*GP*TP*(CX2)P*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | 著者 | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | 登録日 | 2011-10-12 | | 公開日 | 2012-04-25 | | 最終更新日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM.
J.Biol.Chem., 287, 2012
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3V3B
 | | Structure of the Stapled p53 Peptide Bound to Mdm2 | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, SAH-p53-8 stapled-peptide | | 著者 | Baek, S, Kutchukian, P.S, Verdine, G.L, Huber, R, Holak, T.A, Ki Won, L, Popowicz, G.M. | | 登録日 | 2011-12-13 | | 公開日 | 2012-01-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the stapled p53 peptide bound to Mdm2.
J.Am.Chem.Soc., 134, 2012
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4DJS
 | | Structure of beta-catenin in complex with a stapled peptide inhibitor | | 分子名称: | Catenin beta-1, stapled peptide RRWPQ(MK8)ILD(MK8)HVRRVWR | | 著者 | Bowman, B.R, Grossmann, T.N, Yeh, J.T.-H, Verdine, G.L. | | 登録日 | 2012-02-02 | | 公開日 | 2012-10-17 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (3.029 Å) | | 主引用文献 | Inhibition of oncogenic Wnt signaling through direct targeting of beta-catenin.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4G4O
 | | MutM containing M77A mutation bound to oxoG-containing DNA | | 分子名称: | DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | 著者 | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | 登録日 | 2012-07-16 | | 公開日 | 2013-02-20 | | 最終更新日 | 2013-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
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4G4R
 | | MutM containing F114A mutation bound to oxoG-containing DNA | | 分子名称: | DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | 著者 | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | 登録日 | 2012-07-16 | | 公開日 | 2013-02-20 | | 最終更新日 | 2013-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
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4G4N
 | | MutM containing M77A mutation bound to undamaged DNA | | 分子名称: | DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | 著者 | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | 登録日 | 2012-07-16 | | 公開日 | 2013-02-20 | | 最終更新日 | 2013-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
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4G4Q
 | | MutM containing F114A mutation bound to undamaged DNA | | 分子名称: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | | 著者 | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | | 登録日 | 2012-07-16 | | 公開日 | 2013-02-20 | | 最終更新日 | 2013-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.
J.Biol.Chem., 288, 2013
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1HU0
 | | CRYSTAL STRUCTURE OF AN HOGG1-DNA BOROHYDRIDE TRAPPED INTERMEDIATE COMPLEX | | 分子名称: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-OXOGUANINE, ... | | 著者 | Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. | | 登録日 | 2001-01-03 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Product-Assisted Catalysis in base-excision DNA Repair
Nat.Struct.Biol., 10, 2003
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3JR4
 | | MutM interrogating an extrahelical G | | 分子名称: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*G*CP*GP*TP*CP*CP*AP*(GX1)P*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | | 著者 | Qi, Y, Spong, M.C, Verdine, G.L. | | 登録日 | 2009-09-08 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | | 主引用文献 | Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM.
J.Biol.Chem., 285, 2010
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3JR5
 | | MutM lesion recognition control complex with N174C crosslinking site | | 分子名称: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(OGX)P*AP*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | | 著者 | Qi, Y, Spong, M.C, Verdine, G.L. | | 登録日 | 2009-09-08 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.704 Å) | | 主引用文献 | Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM.
J.Biol.Chem., 285, 2010
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3OH6
 | | AlkA Undamaged DNA Complex: Interrogation of a C:G base pair | | 分子名称: | 5'-D(*GP*AP*CP*AP*(BRU)P*GP*AP*AP*(BRU)P*GP*CP*C)-3', 5'-D(*GP*CP*AP*TP*TP*CP*AP*TP*GP*TP*C)-3', DNA-3-methyladenine glycosylase 2 | | 著者 | Bowman, B.R, Lee, S, Wang, S, Verdine, G.L. | | 登録日 | 2010-08-17 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.894 Å) | | 主引用文献 | Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
J.Biol.Chem., 285, 2010
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1A3Q
 | | HUMAN NF-KAPPA-B P52 BOUND TO DNA | | 分子名称: | DNA (5'-D(*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*CP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B P52) | | 著者 | Cramer, P, Larson, C.J, Verdine, G.L, Muller, C.W. | | 登録日 | 1998-01-23 | | 公開日 | 1998-06-11 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.
EMBO J., 16, 1997
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1A66
 | | SOLUTION NMR STRUCTURE OF THE CORE NFATC1/DNA COMPLEX, 18 STRUCTURES | | 分子名称: | CORE NFATC1, DNA (5'-D(*CP*AP*AP*TP*TP*TP*TP*CP*CP*TP*CP*G)-3'), DNA (5'-D(*CP*GP*AP*GP*GP*AP*AP*AP*AP*TP*TP*G)-3') | | 著者 | Zhou, P, Sun, L.J, Doetsch, V, Wagner, G, Verdine, G.L. | | 登録日 | 1998-03-06 | | 公開日 | 1998-06-17 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the core NFATC1/DNA complex.
Cell(Cambridge,Mass.), 92, 1998
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1BNK
 | | HUMAN 3-METHYLADENINE DNA GLYCOSYLASE COMPLEXED TO DNA | | 分子名称: | DNA (5'-D(*GP*AP*CP*AP*TP*GP*YRRP*TP*TP*GP*CP*CP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), PROTEIN (3-METHYLADENINE DNA GLYCOSYLASE) | | 著者 | Lau, A.Y, Schaerer, O.D, Samson, L, Verdine, G.L, Ellenberger, T. | | 登録日 | 1998-07-29 | | 公開日 | 1998-10-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision.
Cell(Cambridge,Mass.), 95, 1998
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1CW9
 | | DNA DECAMER WITH AN ENGINEERED CROSSLINK IN THE MINOR GROOVE | | 分子名称: | 5'-D(*CP*CP*AP*GP*(G47)P*CP*CP*TP*GP*G)-3', CALCIUM ION | | 著者 | van Aalten, D.M.F, Erlanson, D.A, Verdine, G.L, Joshua-Tor, L. | | 登録日 | 1999-08-26 | | 公開日 | 1999-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A structural snapshot of base-pair opening in DNA.
Proc.Natl.Acad.Sci.USA, 96, 1999
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2I5W
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2NOL
 | | Structure of catalytically inactive human 8-oxoguanine glycosylase distal crosslink to oxoG DNA | | 分子名称: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | 著者 | Banerjee, A, Radom, C.T, Verdine, G.L. | | 登録日 | 2006-10-25 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
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2NOH
 | | Structure of catalytically inactive Q315A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA | | 分子名称: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | 著者 | Radom, C.T, Banerjee, A, Verdine, G.L. | | 登録日 | 2006-10-25 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
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2NOF
 | | Structure of Q315F human 8-oxoguanine glycosylase proximal crosslink to 8-oxoguanine DNA | | 分子名称: | 5'-D(*GP*CP*GP*TP*C*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | 著者 | Radom, C.T, Banerjee, A, Verdine, G.L. | | 登録日 | 2006-10-25 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
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