3JR5

MutM lesion recognition control complex with N174C crosslinking site

Summary for 3JR5

• Entry DOI: 10.2210/pdb3jr5/pdb
• Related: 3JR4
• Descriptor: DNA glycosylase, DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(OGX)P*AP*GP*TP*CP*TP*AP*CP*C)-3'), ... (6 entities in total)
• Functional Keywords: dna glycosylase, dna repair, damage search, base extrusion, disulfide crosslinking, dna damage, dna-binding, glycosidase, hydrolase, lyase, metal-binding, multifunctional enzyme, zinc-finger, lyase-dna complex, lyase/dna
• Biological source: Geobacillus stearothermophilus (Geobacillus stearothermophilus)
• Total number of polymer chains: 3
• Total formula weight: 40627.37

Authors

Qi, Y.,Spong, M.C.,Verdine, G.L. (deposition date: 2009-09-08, release date: 2009-11-03, Last modification date: 2023-09-06)

• Primary citation: Qi, Y.,Spong, M.C.,Nam, K.,Karplus, M.,Verdine, G.L.; Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM.; J.Biol.Chem., 285:1468-1478, 2010; PubMed: 19889642; DOI: 10.1074/jbc.M109.069799

Experimental method

X-RAY DIFFRACTION (1.704 Å)