4G4N

MutM containing M77A mutation bound to undamaged DNA

Summary for 4G4N

• Entry DOI: 10.2210/pdb4g4n/pdb
• Related: 4G4O 4G4Q 4G4R
• Descriptor: Formamidopyrimidine-DNA glycosylase, DNA (5'-D(P*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2)P*CP*TP*AP*CP*C)-3'), ... (5 entities in total)
• Functional Keywords: dna glycosylase, dna repair, lesion recognition, base extrusion, disulfide crosslinking, hydrolase-dna complex, hydrolase/dna
• Biological source: Geobacillus stearothermophilus
• Total number of polymer chains: 3
• Total formula weight: 40446.11

Authors

Sung, R.J.,Zhang, M.,Qi, Y.,Verdine, G.L. (deposition date: 2012-07-16, release date: 2013-02-20, Last modification date: 2013-11-20)

• Primary citation: Sung, R.J.,Zhang, M.,Qi, Y.,Verdine, G.L.; Structural and Biochemical Analysis of DNA Helix Invasion by the Bacterial 8-Oxoguanine DNA Glycosylase MutM.; J.Biol.Chem., 288:10012-10023, 2013; PubMed: 23404556; DOI: 10.1074/jbc.M112.415612

Experimental method

X-RAY DIFFRACTION (1.85 Å)