3U6M
| Structural effects of sequence context on lesion recognition by MutM | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*AP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*TP*(8OG)P*GP*TP*(CX2)P*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | Deposit date: | 2011-10-12 | Release date: | 2012-04-25 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J.Biol.Chem., 287, 2012
|
|
3JR4
| MutM interrogating an extrahelical G | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*G*CP*GP*TP*CP*CP*AP*(GX1)P*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Qi, Y, Spong, M.C, Verdine, G.L. | Deposit date: | 2009-09-08 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM. J.Biol.Chem., 285, 2010
|
|
3JR5
| MutM lesion recognition control complex with N174C crosslinking site | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(OGX)P*AP*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Qi, Y, Spong, M.C, Verdine, G.L. | Deposit date: | 2009-09-08 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.704 Å) | Cite: | Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM. J.Biol.Chem., 285, 2010
|
|
3V3B
| Structure of the Stapled p53 Peptide Bound to Mdm2 | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, SAH-p53-8 stapled-peptide | Authors: | Baek, S, Kutchukian, P.S, Verdine, G.L, Huber, R, Holak, T.A, Ki Won, L, Popowicz, G.M. | Deposit date: | 2011-12-13 | Release date: | 2012-01-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the stapled p53 peptide bound to Mdm2. J.Am.Chem.Soc., 134, 2012
|
|
1N39
| Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase | Descriptor: | CALCIUM ION, DNA complement strand, DNA inhibitor strand, ... | Authors: | Norman, D.P, Chung, S.J, Verdine, G.L. | Deposit date: | 2002-10-25 | Release date: | 2003-03-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase Biochemistry, 42, 2003
|
|
1MWJ
| Crystal Structure of a MUG-DNA pseudo substrate complex | Descriptor: | 5'-D(*CP*GP*CP*GP*A*GP*(DU)P*TP*CP*GP*CP*G)-3', G/U mismatch-specific DNA glycosylase | Authors: | Barrett, T.E, Scharer, O, Savva, R, Brown, T, Jiricny, J, Verdine, G.L, Pearl, L.H. | Deposit date: | 2002-09-30 | Release date: | 2002-10-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal Structure of a thwarted mismatch glycosylase DNA repair complex Embo J., 18, 1999
|
|
1N3A
| Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase | Descriptor: | CALCIUM ION, DNA complement strand, DNA inhibitor strand, ... | Authors: | Norman, D.P, Chung, S.J, Verdine, G.L. | Deposit date: | 2002-10-25 | Release date: | 2003-03-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase Biochemistry, 42, 2003
|
|
1N3C
| Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase | Descriptor: | 8-oxoG-containing DNA, CALCIUM ION, DNA complement strand, ... | Authors: | Norman, D.P, Chung, S.J, Verdine, G.L. | Deposit date: | 2002-10-25 | Release date: | 2003-03-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase Biochemistry, 42, 2003
|
|
1HU0
| CRYSTAL STRUCTURE OF AN HOGG1-DNA BOROHYDRIDE TRAPPED INTERMEDIATE COMPLEX | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-OXOGUANINE, ... | Authors: | Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2001-01-03 | Release date: | 2003-02-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Product-Assisted Catalysis in base-excision DNA Repair Nat.Struct.Biol., 10, 2003
|
|
1NFA
| HUMAN TRANSCRIPTION FACTOR NFATC DNA BINDING DOMAIN, NMR, 10 STRUCTURES | Descriptor: | HUMAN TRANSCRIPTION FACTOR NFATC1 | Authors: | Wolfe, S.A, Zhou, P, Dotsch, V, Chen, L, You, A, Ho, S.N, Crabtree, G.R, Wagner, G, Verdine, G.L. | Deposit date: | 1997-01-18 | Release date: | 1997-04-01 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc. Nature, 385, 1997
|
|
1ORN
| |
1ORP
| |
1P59
| Structure of a non-covalent Endonuclease III-DNA Complex | Descriptor: | 5'-D(*AP*AP*GP*AP*CP*GP*(5IU)P*GP*GP*AP*C)-3', 5'-D(TP*GP*(5IU)P*CP*CP*AP*(3DR)P*GP*(5IU)P*CP*T)-3', Endonuclease III, ... | Authors: | Fromme, J.C, Verdine, G.L. | Deposit date: | 2003-04-25 | Release date: | 2003-07-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of a Trapped Endonuclease III-DNA Covalent Intermediate Embo J., 22, 2003
|
|
1L2D
| MutM (Fpg)-DNA Estranged Guanine Mismatch Recognition Complex | Descriptor: | 5'-D(*AP*G*GP*TP*AP*GP*AP*CP*GP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ... | Authors: | Fromme, J.C, Verdine, G.L. | Deposit date: | 2002-02-20 | Release date: | 2002-06-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM. Nat.Struct.Biol., 9, 2002
|
|
1L1Z
| MutM (Fpg) Covalent-DNA Intermediate | Descriptor: | 5'-D(*AP*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ... | Authors: | Fromme, J.C, Verdine, G.L. | Deposit date: | 2002-02-20 | Release date: | 2002-06-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM. Nat.Struct.Biol., 9, 2002
|
|
1L2B
| MutM (Fpg) DNA End-Product Structure | Descriptor: | 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*TP*CP*C*(AD2))-3', 5'-D(P*GP*TP*CP*TP*AP*CP*C)-3', ... | Authors: | Fromme, J.C, Verdine, G.L. | Deposit date: | 2002-02-20 | Release date: | 2002-06-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM. Nat.Struct.Biol., 9, 2002
|
|
1L2C
| MutM (Fpg)-DNA Estranged Thymine Mismatch Recognition Complex | Descriptor: | 5'-D(*AP*G*GP*TP*AP*GP*AP*CP*TP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ... | Authors: | Fromme, J.C, Verdine, G.L. | Deposit date: | 2002-02-20 | Release date: | 2002-06-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM. Nat.Struct.Biol., 9, 2002
|
|
1R2Y
| MutM (Fpg) bound to 8-oxoguanine (oxoG) containing DNA | Descriptor: | 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ... | Authors: | Fromme, J.C, Verdine, G.L. | Deposit date: | 2003-09-30 | Release date: | 2003-10-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | DNA Lesion Recognition by the Bacterial Repair Enzyme MutM. J.Biol.Chem., 278, 2003
|
|
1L1T
| MutM (Fpg) Bound to Abasic-Site Containing DNA | Descriptor: | 5'-D(*AP*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ... | Authors: | Fromme, J.C, Verdine, G.L. | Deposit date: | 2002-02-19 | Release date: | 2002-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into lesion recognition and repair by the bacterial 8-oxoguanine DNA glycosylase MutM. Nat.Struct.Biol., 9, 2002
|
|
1R2Z
| MutM (Fpg) bound to 5,6-dihydrouracil (DHU) containing DNA | Descriptor: | 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*TP*CP*CP*AP*(DHU)P*GP*TP*CP*TP*AP*CP*C)-3', MutM, ... | Authors: | Fromme, J.C, Verdine, G.L. | Deposit date: | 2003-09-30 | Release date: | 2003-10-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | DNA Lesion Recognition by the Bacterial Repair Enzyme MutM. J.Biol.Chem., 278, 2003
|
|
1LWW
| Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-bromoguanine | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-BROMOGUANINE, ... | Authors: | Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2002-06-03 | Release date: | 2003-02-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10, 2003
|
|
1M3H
| Crystal Structure of Hogg1 D268E Mutant with Product Oligonucleotide | Descriptor: | 5'-D(P*GP*CP*GP*TP*CP*CP*AP*(DDX))-3', 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*TP*AP*CP*C)-3', ... | Authors: | Chung, S.J, Verdine, G.L. | Deposit date: | 2002-06-27 | Release date: | 2004-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structures of End Products Resulting from Lesion Processing by a DNA Glycosylase/Lyase Chem.Biol., 11, 2004
|
|
1LWV
| Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-aminoguanine | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-AMINOGUANINE, ... | Authors: | Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2002-06-03 | Release date: | 2003-02-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10, 2003
|
|
1RRQ
| MutY adenine glycosylase in complex with DNA containing an A:oxoG pair | Descriptor: | 5'-D(*TP*GP*TP*CP*CP*AP*AP*GP*TP*CP*T)-3', 5'-D(AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3', CALCIUM ION, ... | Authors: | Fromme, J.C, Banerjee, A, Huang, S.J, Verdine, G.L. | Deposit date: | 2003-12-08 | Release date: | 2004-02-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase Nature, 427, 2004
|
|
1LWY
| hOgg1 Borohydride-Trapped Intermediate without 8-oxoguanine | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-OXOGUANINE DNA GLYCOSYLASE | Authors: | Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2002-06-03 | Release date: | 2003-02-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10, 2003
|
|