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6VZS
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BU of 6vzs by Molmil
Engineered TTLL6 mutant bound to gamma-elongation analog
Descriptor: (2~{S})-2-[[[(3~{R})-3-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2020-02-28
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Nat.Struct.Mol.Biol., 27, 2020
6VZU
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BU of 6vzu by Molmil
TTLL6 bound to alpha-elongation analog
Descriptor: (2~{S})-2-[[[(1~{R})-1-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-oxidanyl-phosphoryl]methyl]pentanedioic acid, (2~{S})-2-[[[(1~{R})-1-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.B, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2020-02-28
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Nat.Struct.Mol.Biol., 27, 2020
6VZQ
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BU of 6vzq by Molmil
Engineered TTLL6 mutant bound to alpha-elongation analog
Descriptor: (2~{S})-2-[[[(1~{R})-1-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, (2~{S})-2-[[[(1~{S})-1-acetamidoethyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Mahalingan, K.K, Keenen, E.K, Strickland, E.K, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2020-02-28
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Nat.Struct.Mol.Biol., 27, 2020
6VZT
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BU of 6vzt by Molmil
TTLL6 bound to ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2020-02-28
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Nat.Struct.Mol.Biol., 27, 2020
6VZV
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BU of 6vzv by Molmil
TTLL6 bound to gamma-elongation analog
Descriptor: (2~{S})-2-[[[(3~{R})-3-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, (2~{S})-2-[[[(3~{S})-3-acetamido-4-oxidanyl-4-oxidanylidene-butyl]-oxidanyl-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2020-02-28
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Nat.Struct.Mol.Biol., 27, 2020
6VZR
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BU of 6vzr by Molmil
Engineered TTLL6 bound to the initiation analog
Descriptor: (2~{S})-2-[[[(3~{R})-3-acetamido-4-(ethylamino)-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, M.E, Tjandra, N, Roll-Mecak, A.
Deposit date:2020-02-28
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes.
Nat.Struct.Mol.Biol., 27, 2020
1YZA
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BU of 1yza by Molmil
The solution structure of a redesigned apocytochrome B562 (Rd-apocyt b562) with the N-terminal helix unfolded
Descriptor: Redesigned apo-cytochrome b562
Authors:Feng, H, Takei, T, Lipsitz, R, Tjandra, N, Bai, Y, Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-02-28
Release date:2005-08-28
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Specific non-native hydrophobic interactions in a hidden folding intermediate: implication for protein folding
Biochemistry, 42, 2003
1YYJ
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BU of 1yyj by Molmil
The NMR solution structure of a redesigned apocytochrome b562:Rd-apocyt b562
Descriptor: redesigned apocytochrome B562
Authors:Feng, H, Takei, J, Lipsitz, R, Tjandra, N, Bai, Y, Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-02-25
Release date:2005-08-25
Last modified:2023-09-27
Method:SOLUTION NMR
Cite:Specific non-native hydrophobic interactions in a hidden folding intermediate: implications for protein folding
Biochemistry, 42, 2003
5T1N
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BU of 5t1n by Molmil
Solution-state NMR structural ensemble of NPr (1-85) refined with RDCs and PCS
Descriptor: Phosphocarrier protein NPr
Authors:Strickland, M, Wang, G, Peterkofsky, A, Tjandra, N.
Deposit date:2016-08-19
Release date:2016-11-16
Last modified:2019-12-04
Method:SOLUTION NMR
Cite:Structure of the NPr:EIN(Ntr) Complex: Mechanism for Specificity in Paralogous Phosphotransferase Systems.
Structure, 24, 2016
5T1O
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BU of 5t1o by Molmil
Solution-state NMR and SAXS structural ensemble of NPr (1-85) in complex with EIN-Ntr (170-424)
Descriptor: Phosphocarrier protein NPr, Phosphoenolpyruvate-protein phosphotransferase PtsP
Authors:Strickland, M, Stanley, A.M, Wang, G, Schwieters, C.D, Buchanan, S, Peterkofsky, A, Tjandra, N.
Deposit date:2016-08-19
Release date:2016-11-16
Last modified:2023-06-14
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Structure of the NPr:EIN(Ntr) Complex: Mechanism for Specificity in Paralogous Phosphotransferase Systems.
Structure, 24, 2016
5VKG
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BU of 5vkg by Molmil
Solution-state NMR structural ensemble of human Tsg101 UEV in complex with tenatoprazole
Descriptor: 4-methoxy-1-(5-methoxy-3H-imidazo[4,5-b]pyridin-2-yl)-3,5-dimethyl-2-(sulfanylmethyl)pyridin-1-ium, Tumor susceptibility gene 101 protein
Authors:Strickland, M, Ehrlich, L.S, Watanabe, S, Khan, M, Strub, M.-P, Luan, C.H, Powell, M.D, Leis, J, Tjandra, N, Carter, C.
Deposit date:2017-04-21
Release date:2017-11-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Tsg101 chaperone function revealed by HIV-1 assembly inhibitors.
Nat Commun, 8, 2017
6BYV
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BU of 6byv by Molmil
Solution NMR structure of cysteine-rich calcium bound domains of very low density lipoprotein receptor
Descriptor: CALCIUM ION, Very low-density lipoprotein receptor
Authors:Banerjee, K, Gruschus, J.M, Tjandra, N, Yakovlev, S, Medved, L.
Deposit date:2017-12-21
Release date:2018-07-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Solution Structure of the Recombinant Fragment Containing Three Fibrin-Binding Cysteine-Rich Domains of the Very Low Density Lipoprotein Receptor.
Biochemistry, 57, 2018
6CMY
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BU of 6cmy by Molmil
Solution NMR Structure Determination of Mouse Melanoregulin
Descriptor: Melanoregulin
Authors:Rout, A.K, Wu, X, Strub, M.P, Starich, M.R, Hammer III, J.A, Tjandra, N.
Deposit date:2018-03-06
Release date:2018-09-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Structure of Melanoregulin Reveals a Role for Cholesterol Recognition in the Protein's Ability to Promote Dynein Function.
Structure, 26, 2018
2L90
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BU of 2l90 by Molmil
Solution structure of murine myristoylated msrA
Descriptor: MYRISTIC ACID, Peptide methionine sulfoxide reductase
Authors:Gruschus, J.M, Lim, J, Piszczek, G, Levine, R.L, Tjandra, N.
Deposit date:2011-01-27
Release date:2012-01-11
Last modified:2012-08-01
Method:SOLUTION NMR
Cite:Characterization and solution structure of mouse myristoylated methionine sulfoxide reductase A.
J.Biol.Chem., 287, 2012
2JZ7
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BU of 2jz7 by Molmil
Solution NMR structure of selenium-binding protein from Methanococcus Vannielii
Descriptor: Selenium binding protein
Authors:Suzuki, M, Stadtman, T.C, Tjandra, N.
Deposit date:2007-12-28
Release date:2008-07-22
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution NMR Structure of Selenium-binding Protein from Methanococcus vannielii.
J.Biol.Chem., 283, 2008
2M64
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BU of 2m64 by Molmil
1H, 13C and 15N Chemical Shift Assignments for Phl p 5a
Descriptor: Phlp5
Authors:Goebl, C, Focke, M, Schrank, E, Madl, T, Kosol, S, Madritsch, C, Flicker, S, Valenta, R, Zangger, K, Tjandra, N.
Deposit date:2013-03-21
Release date:2014-03-26
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Flexible IgE epitope-containing domains of Phl p 5 cause high allergenic activity.
J. Allergy Clin. Immunol., 140, 2017
2KXP
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BU of 2kxp by Molmil
Solution NMR structure of V-1 bound to capping protein (CP)
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, Myotrophin
Authors:Zwolak, A, Fujiwara, I, Hammer III, J.A, Tjandra, N.
Deposit date:2010-05-11
Release date:2010-06-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution NMR structure of V-1 bound to capping protein (CP)
To be Published
2KZ7
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BU of 2kz7 by Molmil
Solution structure of the CARMIL CAH3a/b domain bound to capping protein (CP)
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, Leucine-rich repeat-containing protein 16A
Authors:Zwolak, A, Tjandra, N.
Deposit date:2010-06-12
Release date:2010-07-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the CARMIL CAH3a/b domain bound to capping protein (CP)
To be Published
2L5A
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BU of 2l5a by Molmil
Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3
Descriptor: Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4
Authors:Zhou, Z, Feng, H, Zhou, B, Ghirlando, R, Hu, K, Zwolak, A, Jenkins, L, Xiao, H, Tjandra, N, Wu, C, Bai, Y.
Deposit date:2010-10-28
Release date:2011-03-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3.
Nature, 472, 2011
2M5I
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BU of 2m5i by Molmil
NMR structures of human apoptotic protein tBid in LPPG micelle
Descriptor: BH3-interacting domain death agonist
Authors:Wang, Y, Tjandra, N.
Deposit date:2013-02-25
Release date:2013-11-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Insights of tBid, the Caspase-8-activated Bid, and Its BH3 Domain.
J.Biol.Chem., 288, 2013
2K7W
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BU of 2k7w by Molmil
BAX Activation is Initiated at a Novel Interaction Site
Descriptor: Apoptosis regulator BAX, Bcl-2-like protein 11
Authors:Gavathiotis, E, Suzuki, M, Davis, M.L, Pitter, K, Bird, G.H, Katz, S.G, Tu, H.C, Kim, H, Cheng, E.H, Tjandra, N, Walensky, L.D.
Deposit date:2008-08-27
Release date:2008-10-21
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:BAX activation is initiated at a novel interaction site.
Nature, 455, 2008
2NEF
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BU of 2nef by Molmil
HIV-1 NEF (REGULATORY FACTOR), NMR, 40 STRUCTURES
Descriptor: NEGATIVE FACTOR (F-PROTEIN)
Authors:Grzesiek, S, Bax, A, Clore, G.M, Gronenborn, A.M, Hu, J.S, Kaufman, J, Palmer, I, Stahl, S.J, Tjandra, N, Wingfield, P.T.
Deposit date:1997-02-12
Release date:1997-07-07
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Refined solution structure and backbone dynamics of HIV-1 Nef.
Protein Sci., 6, 1997
4DOM
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BU of 4dom by Molmil
Crystal Structure of the TIR-domain of Human Myeloid Differentiation Primary Response protein (MyD88)
Descriptor: Myeloid differentiation primary response protein MyD88
Authors:Jiang, J.S, Snyder, G.A, Xiao, T.
Deposit date:2012-02-09
Release date:2013-04-10
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 110, 2013
4EO7
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BU of 4eo7 by Molmil
Crystal structure of the TIR domain of human myeloid differentiation primary response protein 88.
Descriptor: MAGNESIUM ION, Myeloid differentiation primary response protein MyD88
Authors:Snyder, G.A, Cirl, C, Jiang, J.S, Chen, P, Smith, T, Xiao, T.S.
Deposit date:2012-04-13
Release date:2013-04-10
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.
Proc.Natl.Acad.Sci.USA, 110, 2013
8EYV
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BU of 8eyv by Molmil
Structure of Beetroot dimer bound to DFHO
Descriptor: (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, POTASSIUM ION, RNA (45-MER)
Authors:Passalacqua, L.F.M, Ferre-D'Amare, A.R.
Deposit date:2022-10-28
Release date:2023-05-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture.
Nat Commun, 14, 2023

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