6C7B
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6C2X
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6C8P
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3B4T
| Crystal structure of Mycobacterium tuberculosis RNase PH, the Mycobacterium tuberculosis Structural Genomics Consortium target Rv1340 | Descriptor: | PHOSPHATE ION, Ribonuclease PH | Authors: | Antczak, A.J, Berger, J.M, Lekin, T, Segelke, B.W, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB), TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2007-10-24 | Release date: | 2007-11-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | 2.1 A Crystal structure of RNase PH from Mycobacterium tuberculosis. To be Published
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1QPR
| QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP | Descriptor: | 1-O-[(R)-hydroxy(phosphonomethyl)phosphoryl]-5-O-phosphono-alpha-D-ribofuranose, MANGANESE (II) ION, PHTHALIC ACID, ... | Authors: | Sharma, V, Grubmeyer, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 1998-10-17 | Release date: | 1998-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target. Structure, 6, 1998
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1QPN
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4O6G
| Rv3902c from M. tuberculosis | Descriptor: | Uncharacterized protein | Authors: | Reddy, B.G, Moates, D.B, Kim, H, Green, T.J, Kim, C, Terwilliger, T.J, Delucas, L.J, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2013-12-20 | Release date: | 2014-03-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | 1.55 angstrom resolution X-ray crystal structure of Rv3902c from Mycobacterium tuberculosis. Acta Crystallogr F Struct Biol Commun, 70, 2014
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1QPO
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6C9N
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6C9S
| Mycobacterium tuberculosis adenosine kinase bound to (2R,3R,4S,5R)-2-(6-([1,1'-biphenyl]-4-ylethynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | Descriptor: | 6-[([1,1'-biphenyl]-4-yl)ethynyl]-9-beta-D-ribofuranosyl-9H-purine, Adenosine kinase, SODIUM ION, ... | Authors: | Crespo, R.A, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2018-01-28 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. J.Med.Chem., 62, 2019
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6C9R
| Mycobacterium tuberculosis adenosine kinase bound to (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(thiophen-3-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol | Descriptor: | 9-beta-D-ribofuranosyl-6-(thiophen-3-yl)-9H-purine, Adenosine kinase, GLYCEROL, ... | Authors: | Crespo, R.A, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2018-01-28 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. J.Med.Chem., 62, 2019
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6C9Q
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6C67
| Mycobacterium tuberculosis adenosine kinase bound to iodotubercidin | Descriptor: | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, Adenosine kinase, GLYCEROL, ... | Authors: | Crespo, R.A, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2018-01-17 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. J.Med.Chem., 62, 2019
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6C9P
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6C9V
| Mycobacterium tuberculosis adenosine kinase bound to (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(4-phenylpiperazin-1-yl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol | Descriptor: | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(4-phenylpiperazin-1-yl)-9H-purin-9-yl]tetrahydrofuran-3,4-diol, Adenosine kinase, GLYCEROL, ... | Authors: | Crespo, R.A, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2018-01-28 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase. J.Med.Chem., 62, 2019
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1NYO
| Solution structure of the antigenic TB protein MPT70/MPB70 | Descriptor: | Immunogenic protein MPT70 | Authors: | Bloemink, M.J, Dentten, E, Hewinson, R.G, Williamson, R.A, Carr, M.D, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-02-13 | Release date: | 2003-08-19 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of the Mycobacterium tuberculosis complex protein MPB70: from tuberculosis pathogenesis to inherited human corneal desease J.Biol.Chem., 278, 2003
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1NXJ
| Structure of Rv3853 from Mycobacterium tuberculosis | Descriptor: | GLYOXYLIC ACID, L(+)-TARTARIC ACID, Probable S-adenosylmethionine:2-demethylmenaquinone methyltransferase | Authors: | Johnston, J.M, Arcus, V.L, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-02-10 | Release date: | 2003-07-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of a Putative Methyltransferase from Mycobacterium tuberculosis: Misannotation of a Genome Clarified by Protein Structural Analysis J.Bacteriol., 185, 2003
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4ZOK
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1UPI
| Mycobacterium tuberculosis rmlC epimerase (Rv3465) | Descriptor: | DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE | Authors: | Kim, C.-Y, Naranjo, C, Waldo, G.S, Lekin, T, Segelke, B.W, Kantardjieff, K.A, Zemla, A, Terwilliger, T, Rupp, B, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-10-05 | Release date: | 2003-10-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mycobacterium Tuberculosis Rmlc Epimerase (Rv3465): A Promising Drug-Target Structure in the Rhamnose Pathway Acta Crystallogr.,Sect.D, 60, 2004
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4ZOJ
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4ZOF
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1NFF
| Crystal structure of Rv2002 gene product from Mycobacterium tuberculosis | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative oxidoreductase Rv2002 | Authors: | Yang, J.K, Park, M.S, Waldo, G.S, Suh, S.W, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2002-12-14 | Release date: | 2002-12-30 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis Proc.Natl.Acad.Sci.USA, 100, 2003
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1O6Y
| Catalytic domain of PknB kinase from Mycobacterium tuberculosis | Descriptor: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SERINE/THREONINE-PROTEIN KINASE PKNB | Authors: | Ortiz-Lombardia, M, Pompeo, F, Boitel, B, Alzari, P.M, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2002-10-21 | Release date: | 2003-01-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the Catalytic Domain of the Pknb Serine/Threonine Kinase from Mycobacterium Tuberculosis J.Biol.Chem., 278, 2003
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1W30
| PyrR of Mycobacterium Tuberculosis as a potential drug target | Descriptor: | PYRR BIFUNCTIONAL PROTEIN | Authors: | Kantardjieff, K.A, Vasquez, C, Castro, P, Warfel, N.N, Rho, B.-S, Lekin, T, Kim, C.-Y, Segelke, B.W, Terwilliger, T, Rupp, B, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2004-07-11 | Release date: | 2004-09-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of Pyrr (Rv1379) from Mycobacterium Tuberculosis: A Persistence Gene and Protein Drug Target Acta Crystallogr.,Sect.D, 61, 2005
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1RFE
| Crystal structure of conserved hypothetical protein Rv2991 from Mycobacterium tuberculosis | Descriptor: | hypothetical protein Rv2991 | Authors: | Benini, S, Haouz, A, Proux, F, Betton, J.M, Alzari, P, Dodson, G.G, Wilson, K.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-11-08 | Release date: | 2004-12-28 | Last modified: | 2019-04-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of Rv2991 from Mycobacterium tuberculosis: An F420binding protein with unknown function. J. Struct. Biol., 2019
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