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8TLZ
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BU of 8tlz by Molmil
Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys
Descriptor: (2S)-2-hydroxybutanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2023-07-27
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys.
Heliyon, 10, 2024
7SJQ
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BU of 7sjq by Molmil
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T-cell engager
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cystine-dense peptide, GLYCEROL, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2021-10-18
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
7SRK
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BU of 7srk by Molmil
Single chain trimer HLA-A*24:02 (Y108C, A163C) with 8mer peptide YPPVPETF
Descriptor: RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-08
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
7SR4
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BU of 7sr4 by Molmil
Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDLYC
Descriptor: Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-07
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
7SR5
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BU of 7sr5 by Molmil
Single chain trimer HLA-A*02:01 (Y108C, A163C) with Wilms tumor protein peptide RMFPNAPYL
Descriptor: VHH, Wilms tumor protein peptide,Beta-2-microglobulin,MHC class I antigen chimera
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-07
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
7ST3
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BU of 7st3 by Molmil
Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity
Descriptor: Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-11
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
7SR0
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BU of 7sr0 by Molmil
Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPET
Descriptor: PHOSPHATE ION, Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-07
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
7SR3
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BU of 7sr3 by Molmil
Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDL
Descriptor: Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-07
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
7SQP
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BU of 7sqp by Molmil
Single chain trimer HLA-A*02:01 (Y108C) with HPV.16 E7 peptide YMLDLQPETTDL
Descriptor: Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-05
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
7SSH
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BU of 7ssh by Molmil
Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC
Descriptor: Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-11
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
7STG
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BU of 7stg by Molmil
Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity
Descriptor: RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-12
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
6OL6
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BU of 6ol6 by Molmil
Structure of iglb12 scFv in complex with anti-idiotype ib2 Fab
Descriptor: CHLORIDE ION, ib2 Heavy Chain, ib2 Light Chain, ...
Authors:Weidle, C, Pancera, M, Gewe, M.
Deposit date:2019-04-15
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
6OL5
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BU of 6ol5 by Molmil
Structure of iglb12 Fab in complex with anti-idiotype ib3 Fab
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, AMMONIUM ION, CHLORIDE ION, ...
Authors:Weidle, C, Pancera, M.
Deposit date:2019-04-15
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
3TNY
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BU of 3tny by Molmil
Structure of YfiY from Bacillus cereus bound to the siderophore iron (III) schizokinen
Descriptor: YfiY (ABC transport system substrate-binding protein), [2-(hydroxy-kappaO)-4-[(3-{(hydroxy-kappaO)[1-(hydroxy-kappaO)ethenyl]amino}propyl)amino]-2-{2-[(3-{(hydroxy-kappaO)[1- (hydroxy-kappaO)ethenyl]amino}propyl)amino]-2-oxoethyl}-4-oxobutanoato(6-)-kappaO]iron
Authors:Clifton, M.C.
Deposit date:2011-09-02
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Parsing the functional specificity of Siderocalin / Lipocalin 2 / NGAL for siderophores and related small-molecule ligands
To be Published
3TZS
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BU of 3tzs by Molmil
Crystal structure of Neutrophil gelatinase-associated lipocalin NGAL (C87S mutant) in complex with fragment 1026, phenylurea
Descriptor: 1,2-ETHANEDIOL, 1-phenylurea, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-09-27
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Parsing the functional specificity of Siderocalin / Lipocalin 2 / NGAL for siderophores and related small-molecule ligands
To be published, 7
3K3L
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BU of 3k3l by Molmil
Crystal structure of Siderocalin (NGAL, Lipocalin 2) complexed with apo Enterobactin
Descriptor: 2,3-DIHYDROXY-BENZOIC ACID, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, CHLORIDE ION, ...
Authors:Clifton, M.C.
Deposit date:2009-10-02
Release date:2010-08-18
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Parsing the functional specificity of Siderocalin / Lipocalin 2 / NGAL for siderophores and related small-molecule ligands
To be Published
3LRR
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BU of 3lrr by Molmil
Crystal structure of human RIG-I CTD bound to a 12 bp AU rich 5' ppp dsRNA
Descriptor: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(ATP)P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*U)-3'), ZINC ION
Authors:Li, P.
Deposit date:2010-02-11
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
3LEF
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BU of 3lef by Molmil
Crystal structure of HIV epitope-scaffold 4E10_S0_1Z6NA_001
Descriptor: 1,2-ETHANEDIOL, Uncharacterized protein 4E10_S0_1Z6NA_001 (T18)
Authors:Holmes, M.A.
Deposit date:2010-01-14
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LF6
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BU of 3lf6 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_1XIZA_S0_001_N
Descriptor: PHOSPHATE ION, Putative phosphotransferase system
Authors:Holmes, M.A.
Deposit date:2010-01-15
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LG7
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BU of 3lg7 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_S0_1EZ3A_002_C
Descriptor: 4E10_S0_1EZ3A_002_C (T246), SULFATE ION
Authors:Holmes, M.A.
Deposit date:2010-01-19
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LH2
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BU of 3lh2 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex
Descriptor: 4E10_1VI7A_S0_002_N (T88), Fv 4E10 heavy chain, Fv 4E10 light chain
Authors:Holmes, M.A.
Deposit date:2010-01-21
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LHP
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BU of 3lhp by Molmil
Crystal structure of HIV epitope-scaffold 4E10_D0_1ISEA_004_N 4E10 Fv complex
Descriptor: 1,2-ETHANEDIOL, 4E10_D0_1ISEA_004_N (T93), Fv 4E10 heavy chain, ...
Authors:Holmes, M.A.
Deposit date:2010-01-22
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LF9
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BU of 3lf9 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_D0_1IS1A_001_C
Descriptor: 4E10_D0_1IS1A_001_C (T161)
Authors:Holmes, M.A.
Deposit date:2010-01-16
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LRN
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BU of 3lrn by Molmil
Crystal structure of human RIG-I CTD bound to a 14 bp GC 5' ppp dsRNA
Descriptor: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION
Authors:Li, P.
Deposit date:2010-02-11
Release date:2010-06-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
3MDS
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BU of 3mds by Molmil
MAGANESE SUPEROXIDE DISMUTASE FROM THERMUS THERMOPHILUS
Descriptor: MANGANESE (III) ION, MANGANESE SUPEROXIDE DISMUTASE
Authors:Ludwig, M.L, Metzger, A.L, Pattridge, K.A, Stallings, W.C.
Deposit date:1993-10-20
Release date:1994-01-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Manganese superoxide dismutase from Thermus thermophilus. A structural model refined at 1.8 A resolution.
J.Mol.Biol., 219, 1991

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