1BYU
 
 | | CANINE GDP-RAN | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (GTP-BINDING PROTEIN RAN) | | 著者 | Stewart, M, Kent, H.M, Mccoy, A.J. | | 登録日 | 1998-10-18 | | 公開日 | 1998-12-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
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1EQ6
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5BXQ
 | | Structure of the NTF2:RanGDP complex | | 分子名称: | GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Stewart, M. | | 登録日 | 2015-06-09 | | 公開日 | 2015-07-01 | | 最終更新日 | 2019-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for molecular recognition between nuclear transport factor 2 (NTF2) and the GDP-bound form of the Ras-family GTPase Ran.
J.Mol.Biol., 277, 1998
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3RAN
 | | CANINE GDP-RAN Q69L MUTANT | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (GTP-BINDING NUCLEAR PROTEIN RAN) | | 著者 | Stewart, M, Kent, H.M, Mccoy, A.J. | | 登録日 | 1998-10-19 | | 公開日 | 1998-12-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2).
J.Mol.Biol., 284, 1998
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5OWU
 | | Kap95:Nup1 complex | | 分子名称: | Importin subunit beta-1, Nucleoporin NUP1 | | 著者 | Stewart, M. | | 登録日 | 2017-09-04 | | 公開日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the high-affinity binding of nucleoporin Nup1p to the Saccharomyces cerevisiae importin-beta homologue, Kap95p.
J. Mol. Biol., 349, 2005
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4U5L
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4U5V
 | | IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR | | 分子名称: | Importin subunit alpha-1, N~2~-{[5-(pyridin-3-yl)thiophen-2-yl]methyl}-L-lysinamide | | 著者 | Stewart, M, Valkov, E, Holvey, R.S. | | 登録日 | 2014-07-25 | | 公開日 | 2015-05-13 | | 最終更新日 | 2015-07-08 | | 実験手法 | X-RAY DIFFRACTION (1.968 Å) | | 主引用文献 | Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
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4U5N
 | | IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR | | 分子名称: | Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide | | 著者 | Stewart, M, Valkov, E, Holvey, R.S. | | 登録日 | 2014-07-25 | | 公開日 | 2015-05-13 | | 最終更新日 | 2015-07-08 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
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4U5S
 | | IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR | | 分子名称: | Importin subunit alpha-1, N-[(2S)-2-[(N~2~-acetyl-D-lysyl)amino]-3-(pyridin-3-ylmethoxy)propyl]-L-allothreonyl-D-phenylalaninamide | | 著者 | Stewart, M, Valkov, E, Holvey, R.S. | | 登録日 | 2014-07-25 | | 公開日 | 2015-05-13 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
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4U54
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4U58
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4U5O
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4U5U
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5L2L
 | | Nab2 Zn fingers 5-7 bound to A11G RNA | | 分子名称: | Nab2p, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*G)-3'), ZINC ION | | 著者 | Stewart, M, Aibara, S. | | 登録日 | 2016-08-02 | | 公開日 | 2016-12-21 | | 最終更新日 | 2017-06-14 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural basis for the dimerization of Nab2 generated by RNA binding provides insight into its contribution to both poly(A) tail length determination and transcript compaction in Saccharomyces cerevisiae.
Nucleic Acids Res., 45, 2017
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5L3T
 | | Structure of the Saccharomyces cerevisiae TREX-2 complex | | 分子名称: | 26S proteasome complex subunit SEM1, Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1, ... | | 著者 | Stewart, M, Aibara, S. | | 登録日 | 2016-05-24 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (4.927 Å) | | 主引用文献 | The Sac3 TPR-like region in the Saccharomyces cerevisiae TREX-2 complex is more extensive but independent of the CID region.
J. Struct. Biol., 195, 2016
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5C5W
 | | 1.25 A resolution structure of an RNA 20-mer | | 分子名称: | RNA (5'-R(P*CP*CP*UP*GP*AP*GP*UP*UP*CP*AP*AP*UP*UP*CP*UP*AP*GP*CP*G)-3') | | 著者 | Stewart, M, Valkov, E. | | 登録日 | 2015-06-22 | | 公開日 | 2015-10-14 | | 最終更新日 | 2017-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | 1.25 angstrom resolution structure of an RNA 20-mer that binds to the TREX2 complex.
Acta Crystallogr.,Sect.F, 71, 2015
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1WA5
 | | Structure of the Cse1:Imp-alpha:RanGTP complex | | 分子名称: | GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ... | | 著者 | Stewart, M. | | 登録日 | 2004-10-23 | | 公開日 | 2004-12-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
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4LJ0
 | | Nab2 Zn fingers complexed with polyadenosine | | 分子名称: | ACETATE ION, MAGNESIUM ION, Nab2, ... | | 著者 | Stewart, M, Kuhlmann, S.I, Valkov, E. | | 登録日 | 2013-07-04 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for the molecular recognition of polyadenosine RNA by Nab2 Zn fingers.
Nucleic Acids Res., 42, 2014
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5UBP
 | | TREX2 M-region | | 分子名称: | 26S proteasome complex subunit SEM1, Leucine permease transcriptional regulator, Nuclear mRNA export protein THP1 | | 著者 | Stewart, M, Gordon, J. | | 登録日 | 2016-12-21 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of the Sac3 RNA-binding M-region in the Saccharomyces cerevisiae TREX-2 complex.
Nucleic Acids Res., 45, 2017
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2BVU
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3KJL
 | | Sgf11:Sus1 complex | | 分子名称: | Protein SUS1, SAGA-associated factor 11 | | 著者 | Stewart, M, Ellisdon, A.M. | | 登録日 | 2009-11-03 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1.
J.Biol.Chem., 285, 2010
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3KIK
 | | Sgf11:Sus1 complex | | 分子名称: | Protein SUS1, SAGA-associated factor 11 | | 著者 | Stewart, M, Ellisdon, A.M. | | 登録日 | 2009-11-02 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1
J.Biol.Chem., 285, 2010
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4C31
 | | Nup1:Sac3:Sus1 complex | | 分子名称: | NUCLEAR MRNA EXPORT PROTEIN SAC3, NUCLEOPORIN NUP1, PROTEIN SUS1 | | 著者 | Stewart, M, Jani, D. | | 登録日 | 2013-08-21 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis for Binding the Trex2 Complex to Nuclear Pores, Gal1 Localisation and Mrna Export.
Nucleic Acids Res., 42, 2014
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4DHX
 | | ENY2:GANP complex | | 分子名称: | 80 kDa MCM3-associated protein, Enhancer of yellow 2 transcription factor homolog | | 著者 | Stewart, M, Jani, D. | | 登録日 | 2012-01-30 | | 公開日 | 2012-06-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export.
Nucleic Acids Res., 40, 2012
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3FWB
 | | Sac3:Sus1:Cdc31 complex | | 分子名称: | Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1 | | 著者 | Stewart, M, Jani, D. | | 登録日 | 2009-01-17 | | 公開日 | 2009-04-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export.
Mol.Cell, 33, 2009
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