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Crystal structure of a Putative aldehyde dehydrogenase family protein Burkholderia cenocepacia J2315 in complex with partially reduced NADH
Descriptor:	1,2-ETHANEDIOL, BETA-6-HYDROXY-1,4,5,6-TETRHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2018-05-02
Release date:	2018-08-29
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Crystal structure of a Putative aldehyde dehydrogenase family protein Burkholderia cenocepacia J2315 in complex with partially reduced NADH TO BE PUBLISHED

6D6J

Crystal structure of HIT family hydrolase from Legionella pneumophila Philadelphia 1
Descriptor:	CHLORIDE ION, HIT family hydrolase, ZINC ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2018-04-21
Release date:	2018-05-02
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (1.35 Å)
Cite:	Crystal structure of HIT family hydrolase from Legionella pneumophila Philadelphia 1 to be published

7R7N

SARS-CoV-2 spike in complex with the S2D106 neutralizing antibody Fab fragment (local refinement of the RBD and S2D106)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S2D106 FAB heavy chain, S2D106 FAB light chain, ...
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-06-25
Release date:	2021-07-21
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY (3.95 Å)
Cite:	SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape. Nature, 597, 2021

7RCR

Crystal Structure of the refolded Hemagglutinin head domain of Influenza A virus A/Ohio/09/2015
Descriptor:	1,2-ETHANEDIOL, Hemagglutinin
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-07-08
Release date:	2021-08-04
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Crystal Structure of the refolded Hemagglutinin head domain of Influenzavirus A Influenza A virus A/Ohio/09/2015 to be published

7RA8

SARS-CoV-2 S glycoprotein in complex with S2X259 Fab
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fab S2X259 Fab variable domain, ...
Authors:	Veesler, D, Tortorici, M.A, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-06-30
Release date:	2021-08-04
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Broad sarbecovirus neutralization by a human monoclonal antibody. Nature, 597, 2021

7RAL

SARS-CoV-2 S bound to S2X259 Fab (local refinement of the RBD/S2X259 variable domains)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2X259 Fab heavy chain, S2X259 Fab light chain, ...
Authors:	Veesler, D, Tortorici, M.A, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-07-01
Release date:	2021-08-04
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY
Cite:	Broad sarbecovirus neutralization by a human monoclonal antibody. Nature, 597, 2021

7RBX

Crystal structure of isocitrate lyase and phosphorylmutase:isocitrate lyase from Brucella melitensis biovar Abortus 2308 bound to itaconic acid
Descriptor:	1,2-ETHANEDIOL, 2-methylidenebutanedioic acid, Isocitrase, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Edwards, T.E, Abendroth, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-07-06
Release date:	2021-10-06
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice. Plos Pathog., 17, 2021

7RZM

Crystal Structure of dnaN DNA polymerase III beta subunit from Stenotrophomonas maltophilia K279a
Descriptor:	DNA polymerase III subunit beta
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-08-27
Release date:	2021-10-20
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	Crystal Structure of dnaN DNA polymerase III beta subunit from Stenotrophomonas maltophilia K279a To Be Published

7RZO

Crystal structure of a dihydrofolate reductase (folA) from Stenotrophomonas maltophilia
Descriptor:	1,2-ETHANEDIOL, CHLORIDE ION, Dihydrofolate reductase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-08-27
Release date:	2021-10-20
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal Structure of dihydrofolate reductase from Stenotrophomonas maltophilia K279a to be published

7RHE

Crystal Structure of ROK family protein from Burkholderia vietnamiensis G4
Descriptor:	ROK family protein
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-07-16
Release date:	2021-11-17
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Crystal Structure of ROK family protein from Burkholderia vietnamiensis G4 to be published

3KRS

Structure of Triosephosphate Isomerase from Cryptosporidium Parvum at 1.55A Resolution
Descriptor:	SODIUM ION, Triosephosphate isomerase, UNKNOWN ATOM OR ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2009-11-19
Release date:	2009-12-01
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.55 Å)
Cite:	Structure of triosephosphate isomerase from Cryptosporidium parvum. Acta Crystallogr.,Sect.F, 67, 2011

3L56

Crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/viet nam/1203/2004 (h5n1)
Descriptor:	Polymerase PB2
Authors:	Staker, B.L, Edwards, T, Eric, S, Raymond, A, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2009-12-21
Release date:	2010-03-09
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Biological and structural characterization of a host-adapting amino acid in influenza virus. Plos Pathog., 6, 2010

5BT9

Crystal Structure of FolM Alternative dihydrofolate reductase 1 from Brucella canis complexed with NADP
Descriptor:	3-oxoacyl-(Acyl-carrier-protein) reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2015-06-02
Release date:	2015-07-29
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis. Acta Crystallogr.,Sect.F, 78, 2022

4E51

Crystal structure of a histidyl-tRNA synthetase HisRS from Burkholderia thailandensis bound to histidine
Descriptor:	HISTIDINE, Histidine--tRNA ligase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-03-13
Release date:	2012-03-28
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms. Sci Rep, 7, 2017

4OH7

Crystal structure of Ornithine carbamoyltransferase from Brucella melitensis
Descriptor:	1,2-ETHANEDIOL, CHLORIDE ION, Ornithine carbamoyltransferase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2014-01-17
Release date:	2014-02-26
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	Crystal structure of Ornithine carbamoyltransferase from Brucella melitensis To be Published

4EXQ

CRYSTAL STRUCTURE of UROPORPHYRINOGEN DECARBOXYLASE (UPD) FROM BURKHOLDERIA THAILANDENSIS E264
Descriptor:	SODIUM ION, Uroporphyrinogen decarboxylase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-04-30
Release date:	2012-05-16
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4EMD

Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to CMP and SO4
Descriptor:	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CYTIDINE-5'-MONOPHOSPHATE, SULFATE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-04-11
Release date:	2012-04-25
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4EU1

Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei
Descriptor:	1,2-ETHANEDIOL, CHLORIDE ION, Mitochondrial aspartate aminotransferase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-04-25
Release date:	2012-05-16
Last modified:	2023-12-06
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr F Struct Biol Commun, 71, 2015

4EGE

Crystal Structure of Dipeptidase PepE from Mycobacterium ulcerans
Descriptor:	1,2-ETHANEDIOL, Dipeptidase PepE, UNKNOWN ATOM OR ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-03-30
Release date:	2012-04-25
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015

4F32

Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase II from Burkholderia vietnamiensis in complex with platencin
Descriptor:	1,2-ETHANEDIOL, 2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-05-08
Release date:	2012-05-23
Last modified:	2014-02-12
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4F40

X-ray crystal structure of Apo prostaglandin f synthase from Leishmania major Friedlin
Descriptor:	1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-05-09
Release date:	2012-06-13
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallogr F Struct Biol Commun, 71, 2015

4F2G

The Crystal Structure of Ornithine carbamoyltransferase from Burkholderia thailandensis E264
Descriptor:	1,2-ETHANEDIOL, Ornithine carbamoyltransferase 1, PHOSPHATE ION
Authors:	Craig, T.K, Fox, D, Staker, B, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-05-07
Release date:	2012-05-30
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4F2N

Crystal structure of iron superoxide dismutase from Leishmania major
Descriptor:	FE (II) ION, Superoxide dismutase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-05-08
Release date:	2012-05-16
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures. Acta Crystallogr F Struct Biol Commun, 71, 2015

4O8K

Crystal structure of Type III pantothenate kinase from Burkholderia thailandensis, apo structure
Descriptor:	1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2013-12-28
Release date:	2014-01-15
Last modified:	2023-12-06
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Crystal structure of Type III pantothenate kinase from Burkholderia thailandensis, apo structure To be Published

8FUY

Glucose-6-phosphate 1-dehydrogenase (G6PDH) from Crithidia fasciculata (citrate bound)
Descriptor:	CHLORIDE ION, CITRIC ACID, Glucose-6-phosphate 1-dehydrogenase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2023-01-18
Release date:	2023-02-08
Method:	X-RAY DIFFRACTION (2.45 Å)
Cite:	Glucose-6-phosphate 1-dehydrogenase (G6PDH) from Crithidia fasciculata (citrate bound) To be published

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