3R0Q
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1A36
| TOPOISOMERASE I/DNA COMPLEX | 分子名称: | DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*A P*TP*TP*TP*TP*T)- 3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*C P*TP*TP*TP*TP*T)- 3'), TOPOISOMERASE I | 著者 | Stewart, L, Redinbo, M.R, Qiu, X, Champoux, J.J, Hol, W.G.J. | 登録日 | 1998-01-29 | 公開日 | 1998-08-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A model for the mechanism of human topoisomerase I. Science, 279, 1998
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7SVE
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7SVK
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7SVF
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7SVH
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7SVG
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7SVI
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7SVJ
| Bile Salt Hydrolase from Lactobacillus ingluviei | 分子名称: | CALCIUM ION, Choloylglycine hydrolase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Walker, M.E, Patel, S, Redinbo, M.R. | 登録日 | 2021-11-19 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut. Nat Microbiol, 8, 2023
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7U4C
| Borrelia burgdorferi HtpG N-terminal domain (1-228) in complex with BX-2819 | 分子名称: | Chaperone protein HtpG, ethyl (4-{3-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-5-sulfanyl-4H-1,2,4-triazol-4-yl}benzyl)carbamate | 著者 | Kowalewski, M.E, Lietzan, A, Haystead, T, Redinbo, M.R. | 登録日 | 2022-02-28 | 公開日 | 2023-03-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Targeting Borrelia burgdorferi HtpG with a berserker molecule, a strategy for anti-microbial development. Cell Chem Biol, 2023
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5FF5
| Crystal Structure of SeMet PaaA | 分子名称: | GLYCEROL, NICKEL (II) ION, PaaA, ... | 著者 | Biernat, K.B, Redinbo, M.R. | 登録日 | 2015-12-17 | 公開日 | 2016-04-27 | 最終更新日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (2.933 Å) | 主引用文献 | Post-translational Claisen Condensation and Decarboxylation en Route to the Bicyclic Core of Pantocin A. J.Am.Chem.Soc., 138, 2016
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5I7J
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5I7K
| Crystal Structure of Human SPLUNC1 Dolphin Mutant D1 (G58A, S61A, G62E, G63D, G66D, I67T) | 分子名称: | BPI fold-containing family A member 1 | 著者 | Walton, W.G, Redinbo, M.R. | 登録日 | 2016-02-17 | 公開日 | 2016-05-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.552 Å) | 主引用文献 | Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1. Biochemistry, 55, 2016
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5I7L
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5UJ6
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2HRQ
| Crystal structure of Human Liver Carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Soman (GD) | 分子名称: | (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Liver carboxylesterase 1, ... | 著者 | Fleming, C.D, Redinbo, M.R. | 登録日 | 2006-07-20 | 公開日 | 2007-05-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of Human Carboxylesterase 1 in Covalent Complexes with the Chemical Warfare Agents Soman and Tabun. Biochemistry, 46, 2007
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2O9I
| Crystal Structure of the Human Pregnane X Receptor LBD in complex with an SRC-1 coactivator peptide and T0901317 | 分子名称: | N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, Nuclear Receptor Coactivator 1 isoform 3, Orphan nuclear receptor PXR | 著者 | Xue, Y, Redinbo, M.R. | 登録日 | 2006-12-13 | 公開日 | 2007-01-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the PXR-T1317 complex provides a scaffold to examine the potential for receptor antagonism. Bioorg.Med.Chem., 15, 2007
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2O6L
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3FLD
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3GS3
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6U7J
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6U7I
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6USS
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6UST
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1NH3
| Human Topoisomerase I Ara-C Complex | 分子名称: | 5'-D(*(GNG)P*GP*AP*AP*AP*AP*AP*UP*UP*UP*UP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*UP*(UBB))-3', 5'-D(*AP*AP*AP*AP*AP*TP*UP*UP*UP*UP*CP*(CAR)P*AP*AP*GP*UP*CP*UP*UP*UP*UP*T)-3', ... | 著者 | Chrencik, J.E, Burgin, A.B, Pommier, Y, Stewart, L, Redinbo, M.R. | 登録日 | 2002-12-18 | 公開日 | 2003-03-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Impact of the Leukemia Drug 1-beta-D-Arabinofuranosylcytosine (Ara-C) on the Covalent Human Topoisomerase I-DNA Complex J.Biol.Chem., 278, 2003
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