7SVF

Bile salt hydrolase A from Lactobacillus gasseri with taurine bound

Summary for 7SVF

Entry DOI	10.2210/pdb7svf/pdb
Descriptor	Choloylglycine hydrolase, 2-AMINOETHANESULFONIC ACID, POTASSIUM ION, ... (4 entities in total)
Functional Keywords	bile salt hydrolase, hydrolase
Biological source	Lactobacillus gasseri
Total number of polymer chains	4
Total formula weight	144019.83
Authors	Walker, M.E.,Redinbo, M.R. (deposition date: 2021-11-19, release date: 2023-01-25, Last modification date: 2023-10-25)
Primary citation	Foley, M.H.,Walker, M.E.,Stewart, A.K.,O'Flaherty, S.,Gentry, E.C.,Patel, S.,Beaty, V.V.,Allen, G.,Pan, M.,Simpson, J.B.,Perkins, C.,Vanhoy, M.E.,Dougherty, M.K.,McGill, S.K.,Gulati, A.S.,Dorrestein, P.C.,Baker, E.S.,Redinbo, M.R.,Barrangou, R.,Theriot, C.M. Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut. Nat Microbiol, 8:611-628, 2023 Cited by PubMed: 36914755 DOI: 10.1038/s41564-023-01337-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation