5I7L

Crystal Structure of SPLUNC1 Disulfide Mutant M2 (A48C, V253C)

Summary for 5I7L

Entry DOI	10.2210/pdb5i7l/pdb
Related	5I7J 5I7K
Descriptor	BPI fold-containing family A member 1 (2 entities in total)
Functional Keywords	surfactant, antimicrobial, airway, antimicrobial protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	49990.80
Authors	Walton, W.G.,Redinbo, M.R. (deposition date: 2016-02-17, release date: 2016-05-18, Last modification date: 2023-09-27)
Primary citation	Walton, W.G.,Ahmad, S.,Little, M.S.,Kim, C.S.,Tyrrell, J.,Lin, Q.,Di, Y.P.,Tarran, R.,Redinbo, M.R. Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1. Biochemistry, 55:2979-2991, 2016 Cited by PubMed: 27145151 DOI: 10.1021/acs.biochem.6b00271 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.598 Å)

Structure validation