5YEM
| CATPO mutant - T188F | 分子名称: | CALCIUM ION, Catalase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Yuzugullu Karakus, Y, Balci, S, Goc, G, Pearson, A.R, Yorke, B. | 登録日 | 2017-09-18 | 公開日 | 2018-07-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Investigation of how gate residues in the main channel affect the catalytic activity of Scytalidium thermophilum catalase. Acta Crystallogr D Struct Biol, 80, 2024
|
|
5XY4
| CATPO mutant - V536W | 分子名称: | CALCIUM ION, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase, ... | 著者 | Yuzugullu Karakus, Y, Goc, G, Balci, S, Pearson, A.R, Yorke, B. | 登録日 | 2017-07-06 | 公開日 | 2018-07-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identification of the site of oxidase substrate binding in Scytalidium thermophilum catalase. Acta Crystallogr D Struct Biol, 74, 2018
|
|
5ZZ1
| Probing the active center of catalase-phenol oxidase from Scytalidium thermophilum | 分子名称: | 3-AMINO-1,2,4-TRIAZOLE, CALCIUM ION, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ... | 著者 | Yuzugullu Karakus, Y, Trinh, C.H, Pearson, A.R, Ogel, Z.B, McPherson, M.J. | 登録日 | 2018-05-29 | 公開日 | 2019-05-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Identification of the site of oxidase substrate binding in Scytalidium thermophilum catalase. Acta Crystallogr D Struct Biol, 74, 2018
|
|
4BWL
| Structure of the Y137A mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate, N-acetyl-D-mannosamine and N- acetylneuraminic acid | 分子名称: | 2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE, 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid, N-ACETYLNEURAMINATE LYASE, ... | 著者 | Campeotto, I, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | 登録日 | 2013-07-03 | 公開日 | 2014-02-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, Qm/Mm Simulation and Mutagenesis. Acs Chem.Biol., 9, 2014
|
|
4CRZ
| Direct visualisation of strain-induced protein prost-translational modification | 分子名称: | ACETYL COENZYME *A, ASPARTATE 1-DECARBOXYLASE, MAGNESIUM ION, ... | 著者 | Monteiro, D.C.F, Patel, V, Bartlett, C.P, Grant, T.D, Nozaki, S, Gowdy, J.A, Snell, E.H, Niki, H, Pearson, A.R, Webb, M.E. | 登録日 | 2014-03-02 | 公開日 | 2015-03-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Structure of the Pand/Panz Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A. Chem.Biol., 22, 2015
|
|
4CTG
| The limits of structural plasticity in a picornavirus capsid revealed by a massively expanded equine rhinitis A virus particle | 分子名称: | P1 | 著者 | Bakker, S.E, Groppelli, E, Pearson, A.R, Stockley, P.G, Rowlands, D.J, Ranson, N.A. | 登録日 | 2014-03-13 | 公開日 | 2014-05-21 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (17 Å) | 主引用文献 | Limits of Structural Plasticity in a Picornavirus Capsid Revealed by a Massively Expanded Equine Rhinitis a Virus Particle. J.Virol., 88, 2014
|
|
4CRY
| Direct visualisation of strain-induced protein post-translational modification | 分子名称: | ACETYL COENZYME *A, ASPARTATE 1-DECARBOXYLASE, CHLORIDE ION, ... | 著者 | Monteiro, D.C.F, Patel, V, Bartlett, C.P, Grant, T.D, Nozaki, S, Gowdy, J.A, Snell, E.H, Niki, H, Pearson, A.R, Webb, M.E. | 登録日 | 2014-03-02 | 公開日 | 2015-03-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Direct Visualisation of Strain-Induced Protein Post-Translational Modification To be Published
|
|
4CTF
| The limits of structural plasticity in a picornavirus capsid revealed by a massively expanded equine rhinitis A virus particle | 分子名称: | EQUINE RHINITIS A VIRUS, P1, VP1 | 著者 | Bakker, S.E, Groppelli, E, Pearson, A.R, Stockley, P.G, Rowlands, D.J, Ranson, N.A. | 登録日 | 2014-03-13 | 公開日 | 2014-05-21 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (17 Å) | 主引用文献 | Limits of Structural Plasticity in a Picornavirus Capsid Revealed by a Massively Expanded Equine Rhinitis a Virus Particle. J.Virol., 88, 2014
|
|
4D7Z
| E. coli L-aspartate-alpha-decarboxylase mutant N72Q to a resolution of 1.9 Angstroms | 分子名称: | ASPARTATE 1-DECARBOXYLASE ALPHA CHAIN, ASPARTATE 1-DECARBOXYLASE BETA CHAIN, DI(HYDROXYETHYL)ETHER, ... | 著者 | Bravo, J.P.K, Monteiro, D.C.F, Webb, M.E, Pearson, A.R. | 登録日 | 2014-12-02 | 公開日 | 2016-01-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Structure of the E. Coli L-Aspartate-Alpha-Decarboxylase Mutant N72Q to a Resolution of 1.9 Angstroms To be Published
|
|
4CIZ
| Crystal structure of the complex of the Cellular Retinal Binding Protein with 9-cis-retinal | 分子名称: | L(+)-TARTARIC ACID, RETINAL, RETINALDEHYDE-BINDING PROTEIN 1 | 著者 | Bolze, C.S, Helbling, R.E, Owen, R.L, Pearson, A.R, Pompidor, G, Dworkowski, F, Fuchs, M.R, Furrer, J, Golczak, M, Palczewski, K, Cascella, M, Stocker, A. | 登録日 | 2013-12-18 | 公開日 | 2014-01-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.403 Å) | 主引用文献 | Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity. J.Am.Chem.Soc., 136, 2014
|
|
4CJ6
| Crystal structure of the complex of the Cellular Retinal Binding Protein Mutant R234W with 9-cis-retinal | 分子名称: | RETINAL, RETINALDEHYDE-BINDING PROTEIN 1 | 著者 | Bolze, C.S, Helbling, R.E, Owen, R.L, Pearson, A.R, Pompidor, G, Dworkowski, F, Fuchs, M.R, Furrer, J, Golczak, M, Palczewski, K, Cascella, M, Stocker, A. | 登録日 | 2013-12-19 | 公開日 | 2014-01-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.896 Å) | 主引用文献 | Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-Cis-Retinal Isomerase Activity. J.Am.Chem.Soc., 136, 2014
|
|
4CS0
| Direct visualisation of strain-induced protein post-translational modification | 分子名称: | ACETYL COENZYME *A, ASPARTATE 1-DECARBOXYLASE, MAGNESIUM ION, ... | 著者 | Monteiro, D.C.F, Patel, V, Bartlett, C.P, Grant, T.D, Nozaki, S, Gowdy, J.A, Snell, E.H, Niki, H, Pearson, A.R, Webb, M.E. | 登録日 | 2014-03-02 | 公開日 | 2015-03-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Structure of the Pand/Panz Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A. Chem.Biol., 22, 2015
|
|
6EZZ
| Crystal structure of Escherichia coli amine oxidase mutant E573Q | 分子名称: | CALCIUM ION, COPPER (II) ION, GLYCEROL, ... | 著者 | Gaule, T.G, Smith, M.A, Tych, K.M, Pirrat, P, Trinh, C.H, Pearson, A.R, Knowles, P.F, McPherson, M.J. | 登録日 | 2017-11-16 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Oxygen Activation Switch in the Copper Amine Oxidase of Escherichia coli. Biochemistry, 57, 2018
|
|
6FAX
| Complex of Human CD40 Ectodomain with Lob 7.4 Fab | 分子名称: | Lob 7.4 heavy chain, Lob 7.4 light chain, Tumor necrosis factor receptor superfamily member 5 | 著者 | Orr, C.M, Tews, I, Pearson, A.R. | 登録日 | 2017-12-18 | 公開日 | 2018-02-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies. Cancer Cell, 33, 2018
|
|
2WNZ
| Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in space group P21 crystal form I | 分子名称: | (2S)-2-HYDROXYPROPANOIC ACID, 2-ETHOXYETHANOL, LACTIC ACID, ... | 著者 | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | 登録日 | 2009-07-21 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution. J.Mol.Biol., 404, 2010
|
|
2WKJ
| Crystal structure of the E192N mutant of E. Coli N-acetylneuraminic acid lyase in complex with pyruvate at 1.45A resolution in space group P212121 | 分子名称: | N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL, PYRUVIC ACID | 著者 | Campeotto, I, Carr, S.B, Trinh, C.H, Nelson, A.S, Berry, A, Phillips, S.E.V, Pearson, A.R. | 登録日 | 2009-06-11 | 公開日 | 2009-12-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of an Escherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 angstrom resolution. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 65, 2009
|
|
2WNN
| Structure of wild type E. coli N-acetylneuraminic acid lyase in complex with pyruvate in space group P21 | 分子名称: | N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL, SODIUM ION | 著者 | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | 登録日 | 2009-07-13 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution. J.Mol.Biol., 404, 2010
|
|
2WPB
| Crystal structure of the E192N mutant of E. Coli N-acetylneuraminic acid lyase in complex with pyruvate and the inhibitor (2R,3R)-2,3,4- trihydroxy-N,N-dipropylbutanamide in space group P21 crystal form I | 分子名称: | (2R,3R)-2,3,4-TRIHYDROXY-N,N-DIPROPYLBUTANAMIDE, N-ACETYLNEURAMINATE LYASE | 著者 | Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | 登録日 | 2009-08-03 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution. J.Mol.Biol., 404, 2010
|
|
2XFW
| Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in crystal form III | 分子名称: | N-ACETYLNEURAMINIC ACID LYASE, PENTAETHYLENE GLYCOL, PYRUVIC ACID | 著者 | Campeotto, I, Murshudov, G.N, Bolt, A.H, Trinh, C.H, Phillips, S.E.V, Nelson, A, Pearson, A.R, Berry, A. | 登録日 | 2010-05-28 | 公開日 | 2010-09-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution. To be Published
|
|
2YGY
| Structure of wild type E. coli N-acetylneuraminic acid lyase in space group P21 crystal form II | 分子名称: | CHLORIDE ION, N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL | 著者 | Campeotto, I, Nelson, A, Berry, A, Phillips, S.E.V, Pearson, A.R. | 登録日 | 2011-04-23 | 公開日 | 2012-04-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Pathological macromolecular crystallographic data affected by twinning, partial-disorder and exhibiting multiple lattices for testing of data processing and refinement tools. Sci Rep, 8, 2018
|
|
4AMA
| Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165 in complex with pyruvate | 分子名称: | N-ACETYLNEURAMINATE LYASE | 著者 | Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A. | 登録日 | 2012-03-08 | 公開日 | 2013-01-23 | 最終更新日 | 2019-07-10 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural insights into the recovery of aldolase activity in N-acetylneuraminic acid lyase by replacement of the catalytically active lysine with gamma-thialysine by using a chemical mutagenesis strategy. Chembiochem, 14, 2013
|
|
6RXH
| In-flow serial synchrotron crystallography using a 3D-printed microfluidic device (3D-MiXD): Aspartate alpha-decarboxylase | 分子名称: | Aspartate 1-decarboxylase, UNKNOWN ATOM OR ION | 著者 | Monteiro, D.C.F, von Stetten, D, Pearson, A.R, Trebbin, M. | 登録日 | 2019-06-08 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 3D-MiXD: 3D-printed X-ray-compatible microfluidic devices for rapid, low-consumption serial synchrotron crystallography data collection in flow. Iucrj, 7, 2020
|
|
6RXI
| In-flow serial synchrotron crystallography using a 3D-printed microfluidic device (3D-MiXD): Lysozyme | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Lysozyme C, ... | 著者 | Monteiro, D.C.F, von Stetten, D, Pearson, A.R, Trebbin, M. | 登録日 | 2019-06-08 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 3D-MiXD: 3D-printed X-ray-compatible microfluidic devices for rapid, low-consumption serial synchrotron crystallography data collection in flow. Iucrj, 7, 2020
|
|
6GRR
| Crystal structure of Escherichia coli amine oxidase mutant I342F/E573Q | 分子名称: | Amine oxidase, CALCIUM ION, COPPER (II) ION, ... | 著者 | Gaule, T.G, Smith, M.A, Tych, K.M, Pirrat, P, Trinh, C.H, Pearson, A.R, Knowles, P.F, McPherson, M.J. | 登録日 | 2018-06-12 | 公開日 | 2018-09-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Oxygen Activation Switch in the Copper Amine Oxidase of Escherichia coli. Biochemistry, 57, 2018
|
|
3ZX8
| Cryo-EM reconstruction of native and expanded Turnip Crinkle virus | 分子名称: | CAPSID PROTEIN | 著者 | Bakker, S.E, Robottom, J, Hogle, J.M, Maeda, A, Pearson, A.R, Stockley, P.G, Ranson, N.A, Harrison, S.C. | 登録日 | 2011-08-08 | 公開日 | 2012-07-18 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (11.5 Å) | 主引用文献 | Isolation of an Asymmetric RNA Uncoating Intermediate for a Single-Stranded RNA Plant Virus. J.Mol.Biol., 417, 2012
|
|