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4LKP
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BU of 4lkp by Molmil
Crystal Structure of Apo Human Epidermal Fatty Acid Binding Protein (FABP5)
Descriptor: AMMONIUM ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Armstrong, E.H, Ortlund, E.A.
Deposit date:2013-07-08
Release date:2014-03-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor beta / delta (FABP5-PPAR beta / delta ) signaling pathway.
J.Biol.Chem., 289, 2014
4LKT
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BU of 4lkt by Molmil
Crystal Structure of Human Epidermal Fatty Acid Binding Protein (FABP5) in Complex with Linoleic Acid
Descriptor: AMMONIUM ION, CHLORIDE ION, CITRIC ACID, ...
Authors:Armstrong, E.H, Ortlund, E.A.
Deposit date:2013-07-08
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor beta / delta (FABP5-PPAR beta / delta ) signaling pathway.
J.Biol.Chem., 289, 2014
4MCE
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BU of 4mce by Molmil
Crystal structure of the Gas5 GRE Mimic
Descriptor: Gas5 GREM Fwd, Gas5 GREM Rev, SULFATE ION
Authors:Hudson, W.H, Ortlund, E.A.
Deposit date:2013-08-21
Release date:2014-09-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate.
Nat Commun, 5, 2014
4MCA
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BU of 4mca by Molmil
Crystal Structure of Glycerol Dehydrogenase from Serratia to 1.9A
Descriptor: GLYCEROL, Glycerol dehydrogenase, SODIUM ION, ...
Authors:Musille, P.M, Ortlund, E.A.
Deposit date:2013-08-21
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of glycerol dehydrogenase from Serratia
Acta Crystallogr.,Sect.F, 2014
4MCF
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BU of 4mcf by Molmil
Crystal structure of the Gas5 GRE Mimic
Descriptor: Gas5 GREM Fwd, Gas5 GREM Rev, SULFATE ION
Authors:Hudson, W.H, Ortlund, E.A.
Deposit date:2013-08-21
Release date:2014-11-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate.
Nat Commun, 5, 2014
4PLD
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BU of 4pld by Molmil
Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, in its apo State Bound to a Fragment of Human TIF-2
Descriptor: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Nuclear receptor coactivator 2, Nuclear receptor subfamily 5 group A member 2
Authors:Musille, P.M, Ortlund, E.A.
Deposit date:2014-05-16
Release date:2015-12-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Unexpected Allosteric Network Contributes to LRH-1 Co-regulator Selectivity.
J.Biol.Chem., 291, 2016
7U0Q
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BU of 7u0q by Molmil
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-02
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Patel, A, Ortlund, E.
Deposit date:2022-02-18
Release date:2023-03-01
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
Structure, 31, 2023
7U0X
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BU of 7u0x by Molmil
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-13
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Patel, A, Ortlund, E.
Deposit date:2022-02-19
Release date:2023-03-01
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
Structure, 31, 2023
7UOW
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BU of 7uow by Molmil
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 034_32
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal antibody 034_32 heavy chain, ...
Authors:Patel, A, Ortlund, E.
Deposit date:2022-04-14
Release date:2023-04-19
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
Structure, 31, 2023
4MB8
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BU of 4mb8 by Molmil
Evolutionary history and metabolic insights of ancient mammalian uricases
Descriptor: ACETATE ION, Uricase
Authors:Ortlund, E.O, Murphy, M.N.
Deposit date:2013-08-19
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4009 Å)
Cite:Evolutionary history and metabolic insights of ancient mammalian uricases.
Proc.Natl.Acad.Sci.USA, 111, 2014
7U9D
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BU of 7u9d by Molmil
Crystal Structure of Human Phosphatidylcholine Transfer Protein in Complex with PC(16:0/20:4)
Descriptor: GLYCEROL, Phosphatidylcholine transfer protein, [(2~{R})-1-hexadecanoyloxy-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propan-2-yl] (5~{Z},8~{Z},11~{Z},14~{Z})-icosa-5,8,11,14-tetraenoate
Authors:Druzak, S.A.
Deposit date:2022-03-10
Release date:2023-04-12
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Ligand dependent interaction between PC-TP and PPAR delta mitigates diet-induced hepatic steatosis in male mice.
Nat Commun, 14, 2023
4M8Z
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BU of 4m8z by Molmil
Crystal Structure of SFH3, a phosphatidylinositol transfer protein that integrates phosphoinositide signaling with lipid droplet metabolism
Descriptor: Phosphatidylinositol transfer protein PDR16
Authors:Ortlund, E.O, Pathak, M.C.
Deposit date:2013-08-14
Release date:2014-09-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.928 Å)
Cite:A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis.
Mol Biol Cell, 25, 2014
4N1Y
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BU of 4n1y by Molmil
Crystal Structure of the Pacific Oyster Estrogen Receptor Ligand Binding Domain
Descriptor: Estrogen receptor
Authors:Ortlund, E.O.
Deposit date:2013-10-04
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:Vestigialization of an allosteric switch: genetic and structural mechanisms for the evolution of constitutive activity in a steroid hormone receptor.
PLoS Genet, 10, 2014
4OND
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BU of 4ond by Molmil
Ancestral Steroid Receptor 2 DBD helix mutant - ERE DNA complex
Descriptor: 5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*GP*AP*GP*TP*GP*AP*CP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*CP*TP*GP*AP*CP*CP*TP*G)-3', Ancestral SR2 Helix Mutant, ...
Authors:Ortlund, E.O, Murphy, M.N.
Deposit date:2014-01-28
Release date:2014-10-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.253 Å)
Cite:Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module.
Cell(Cambridge,Mass.), 159, 2014
4OOR
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BU of 4oor by Molmil
Ancestral Steroid Receptor 2 DNA binding domain in complex with a steroid response element
Descriptor: 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3', Ancestral Steroid Receptor 2 DNA binding domain, ...
Authors:Ortlund, E.O, Murphy, M.N.
Deposit date:2014-02-03
Release date:2014-10-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module.
Cell(Cambridge,Mass.), 159, 2014
4OLN
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BU of 4oln by Molmil
Ancestral Steroid Receptor 1 in complex with estrogen response element DNA
Descriptor: 5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*GP*AP*GP*TP*GP*AP*CP*CP*TP*GP*A)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*CP*TP*GP*AP*CP*CP*TP*GP*G)-3', AncSR1, ...
Authors:Ortlund, E.O, Murphy, M.N.
Deposit date:2014-01-24
Release date:2014-10-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module.
Cell(Cambridge,Mass.), 159, 2014
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