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1RH9
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BU of 1rh9 by Molmil
Family GH5 endo-beta-mannanase from Lycopersicon esculentum (tomato)
Descriptor: endo-beta-mannanase
Authors:Oakley, A.J, Bourgault, R, Bewley, J.D, Wilce, M.C.J.
Deposit date:2003-11-14
Release date:2005-04-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Three-dimensional structure of (1,4)-beta-D-mannan mannanohydrolase from tomato fruit.
Protein Sci., 14, 2005
4XR0
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BU of 4xr0 by Molmil
Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- G/T mismatch.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*GP*T)-3'), DNA (5'-D(*AP*TP*TP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3'), ...
Authors:Oakley, A.J.
Deposit date:2015-01-20
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Replisome speed determines the efficiency of the Tus-Ter replication termination barrier.
Nature, 525, 2015
4XR1
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BU of 4xr1 by Molmil
Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- AG/AT mismatch.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*TP*AP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*G)-3'), ...
Authors:Oakley, A.J.
Deposit date:2015-01-20
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Replisome speed determines the efficiency of the Tus-Ter replication termination barrier.
Nature, 525, 2015
4XR2
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BU of 4xr2 by Molmil
Escherichia Coli Replication Terminator Protein (Tus) H114A mutant Complexed With DNA- TerA lock.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DNA (5'-D(*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*C)-3'), ...
Authors:Oakley, A.J.
Deposit date:2015-01-20
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Replisome speed determines the efficiency of the Tus-Ter replication termination barrier.
Nature, 525, 2015
4XR3
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BU of 4xr3 by Molmil
Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- GC(6) swapped.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*TP*AP*CP*TP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3'), DNA (5'-D(*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*GP*T)-3'), ...
Authors:Oakley, A.J.
Deposit date:2015-01-20
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Replisome speed determines the efficiency of the Tus-Ter replication termination barrier.
Nature, 525, 2015
2EWJ
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BU of 2ewj by Molmil
Escherichia Coli Replication Terminator Protein (Tus) Complexed With DNA- Locked form
Descriptor: 5'-D(*T*TP*AP*GP*TP*TP*AP*CP*AP*AP*CP*AP*TP*AP*CP*T)-3', 5'-D(*TP*G*AP*TP*AP*TP*GP*TP*TP*GP*TP*AP*AP*CP*TP*A)-3', DNA replication terminus site-binding protein, ...
Authors:Oakley, A.J, Mulcair, M.D, Schaeffer, P.M, Dixon, N.E.
Deposit date:2005-11-03
Release date:2006-05-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A molecular mousetrap determines polarity of termination of DNA replication in E. coli.
Cell(Cambridge,Mass.), 125, 2006
3EE2
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BU of 3ee2 by Molmil
Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole
Descriptor: GLUTATHIONE, Glutathione-requiring prostaglandin D synthase, MAGNESIUM ION, ...
Authors:Oakley, A.J.
Deposit date:2008-09-04
Release date:2008-09-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D(2) synthase
Eur.J.Med.Chem., 45, 2010
6PNN
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BU of 6pnn by Molmil
Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-(2-methoxyethyl)-N-methylsulfamoyl)phenyl)acetamide
Descriptor: 2-chloro-N-{4-chloro-3-[(2-methoxyethyl)(methyl)sulfamoyl]phenyl}acetamide, Glutathione S-transferase omega-1, L(+)-TARTARIC ACID, ...
Authors:Oakley, A.J.
Deposit date:2019-07-02
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J.Med.Chem., 63, 2020
6PNM
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BU of 6pnm by Molmil
Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(morpholinosulfonyl)phenyl)acetamide
Descriptor: 2-chloro-N-{4-chloro-3-[(morpholin-4-yl)sulfonyl]phenyl}acetamide, Glutathione S-transferase omega-1, L(+)-TARTARIC ACID, ...
Authors:Oakley, A.J.
Deposit date:2019-07-02
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J.Med.Chem., 63, 2020
6PNO
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BU of 6pno by Molmil
Human GSTO1-1 complexed with 2-chloro-N-(4-chloro-3-(N-isopropylsulfamoyl)phenyl)acetamide
Descriptor: 2-chloro-N-{4-chloro-3-[(propan-2-yl)sulfamoyl]phenyl}acetamide, Glutathione S-transferase omega-1, L(+)-TARTARIC ACID, ...
Authors:Oakley, A.J.
Deposit date:2019-07-02
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J.Med.Chem., 63, 2020
8GJ2
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BU of 8gj2 by Molmil
E. coli clamp loader with closed clamp on primed template DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Beta sliding clamp, DNA polymerase III subunit delta, ...
Authors:Oakley, A.J, Xu, Z.-Q, Dixon, N.E.
Deposit date:2023-03-14
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural characterisation of the complete cycle of sliding clamp loading in E. coli
To Be Published
8GJ0
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BU of 8gj0 by Molmil
E. coli clamp loader with open clamp on primed template DNA (form 1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Beta sliding clamp, DNA polymerase III subunit delta, ...
Authors:Oakley, A.J, Xu, Z.-Q, Dixon, N.E.
Deposit date:2023-03-14
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural characterisation of the complete cycle of sliding clamp loading in E. coli
To Be Published
8GJ3
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BU of 8gj3 by Molmil
E. coli clamp loader on primed template DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ...
Authors:Oakley, A.J, Xu, Z.-Q, Dixon, N.E.
Deposit date:2023-03-14
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural characterisation of the complete cycle of sliding clamp loading in E. coli
To Be Published
8GIY
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BU of 8giy by Molmil
E. coli clamp loader with closed clamp
Descriptor: Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ...
Authors:Oakley, A.J, Xu, Z.-Q, Dixon, N.E.
Deposit date:2023-03-14
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural characterisation of the complete cycle of sliding clamp loading in E. coli
To Be Published
8GJ1
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BU of 8gj1 by Molmil
E. coli clamp loader with open clamp on primed template DNA (form 2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Beta sliding clamp, DNA polymerase III subunit delta, ...
Authors:Oakley, A.J, Xu, Z.-Q, Dixon, N.E.
Deposit date:2023-03-14
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural characterisation of the complete cycle of sliding clamp loading in E. coli
To Be Published
8GIZ
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BU of 8giz by Molmil
E. coli clamp loader with open clamp
Descriptor: Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ...
Authors:Oakley, A.J, Xu, Z.-Q, Dixon, N.E.
Deposit date:2023-03-14
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural characterisation of the complete cycle of sliding clamp loading in E. coli
To Be Published
3IBT
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BU of 3ibt by Molmil
Structure of 1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase (QDO)
Descriptor: 1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase
Authors:Oakley, A.J.
Deposit date:2009-07-16
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for cofactor-independent dioxygenation of N-heteroaromatic compounds at the alpha/beta-hydrolase fold.
Proc.Natl.Acad.Sci.USA, 107, 2010
4MZ9
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BU of 4mz9 by Molmil
Revised structure of E. coli SSB
Descriptor: Single-stranded DNA-binding protein
Authors:Oakley, A.J.
Deposit date:2013-09-29
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Intramolecular binding mode of the C-terminus of Escherichia coli single-stranded DNA binding protein determined by nuclear magnetic resonance spectroscopy.
Nucleic Acids Res., 42, 2014
4UXV
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BU of 4uxv by Molmil
Cytoplasmic domain of bacterial cell division protein EzrA
Descriptor: SEPTATION RING FORMATION REGULATOR EZRA
Authors:Cleverley, R.M, Barrett, J.R, Basle, A, Khai-Bui, N, Hewitt, L, Solovyova, A, Xu, Z, Daniela, R.A, Dixon, N.E, Harry, E.J, Oakley, A.J, Vollmer, W, Lewis, R.J.
Deposit date:2014-08-27
Release date:2014-10-22
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (3.961 Å)
Cite:Structure and Function of a Spectrin-Like Regulator of Bacterial Cytokinesis.
Nat.Commun., 5, 2014
4UY3
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BU of 4uy3 by Molmil
Cytoplasmic domain of bacterial cell division protein ezra
Descriptor: SEPTATION RING FORMATION REGULATOR EZRA
Authors:Cleverley, R.M, Barrett, J.R, Basle, A, Khai-Bui, N, Hewitt, L, Solovyova, A, Xu, Z, Daniela, R.A, Dixon, N.E, Harry, E.J, Oakley, A.J, Vollmer, W, Lewis, R.J.
Deposit date:2014-08-28
Release date:2014-10-22
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and Function of a Spectrin-Like Regulator of Bacterial Cytokinesis.
Nat.Commun., 5, 2014
3VLN
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BU of 3vln by Molmil
Human Glutathione Transferase O1-1 C32S Mutant in Complex with Ascorbic Acid
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ASCORBIC ACID, ...
Authors:Brock, J, Board, P.G, Oakley, A.J.
Deposit date:2011-12-02
Release date:2012-05-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases.
J.Mol.Biol., 420, 2012
6WVJ
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BU of 6wvj by Molmil
Cryo-EM structure of Bacillus subtilis RNA Polymerase elongation complex
Descriptor: DNA (5'-D(*TP*GP*TP*CP*GP*GP*GP*CP*GP*TP*CP*CP*GP*CP*GP*CP*GP*CP*C)-3'), DNA (5'-D(P*AP*CP*GP*CP*CP*CP*GP*AP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Newing, T, Tolun, G, Oakley, A.J.
Deposit date:2020-05-06
Release date:2020-11-18
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD.
Nat Commun, 11, 2020
6WVK
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BU of 6wvk by Molmil
Cryo-EM structure of Bacillus subtilis RNA Polymerase in complex with HelD
Descriptor: DNA helicase IV, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Newing, T, Tolun, G, Oakley, A.J.
Deposit date:2020-05-06
Release date:2020-11-18
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD.
Nat Commun, 11, 2020
1UIS
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BU of 1uis by Molmil
The 2.0 crystal structure of eqFP611, a far-red fluorescent protein from the sea anemone Entacmaea quadricolor
Descriptor: ACETIC ACID, CALCIUM ION, red fluorescent protein FP611
Authors:Petersen, J, Wilmann, P.G, Beddoe, T, Oakley, A.J, Devenish, R.J, Prescott, M, Rossjohn, J.
Deposit date:2003-07-21
Release date:2003-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0A crystal structure of eqFP611, a far-red fluorescent protein from the sea anemone Entacmaea quadricolor
J.Biol.Chem., 278, 2003
4ZW2
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BU of 4zw2 by Molmil
Crystal structure of the Mouse voltage gated calcium channel beta subunit isoform 1a in complex with Alpha Interaction Domain peptide.
Descriptor: TRIETHYLENE GLYCOL, Voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-dependent L-type calcium channel subunit beta-1,Voltage-dependent L-type calcium channel subunit beta-1
Authors:Norris, N.C, Oakley, A.J.
Deposit date:2015-05-19
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural and biophysical analyses of the skeletal dihydropyridine receptor beta subunit beta 1a reveal critical roles of domain interactions for stability.
J. Biol. Chem., 292, 2017

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