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8QKS
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BU of 8qks by Molmil
Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to R5.034
Descriptor: Immunoglobulin lambda variable 1-36, R5034HV, Reticulocyte-binding protein-like protein 5
Authors:Wright, N.D, Barrett, J.R, Bradshaw, W.J, Paterson, N.G, MacLean, E.M, Ferreira, L, McHugh, K, Von Delft, F, Koekemoer, L, Draper, S.J.
Deposit date:2023-09-16
Release date:2024-07-31
Last modified:2024-09-18
Method:X-RAY DIFFRACTION (3.994 Å)
Cite:Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype.
Cell, 187, 2024
8QKR
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BU of 8qkr by Molmil
Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to R5.251
Descriptor: R5251VHCH, R5251VLCL, Reticulocyte-binding protein-like protein 5
Authors:Wright, N.D, Barrett, J.R, Bradshaw, W.J, Paterson, N.G, MacLean, E.M, Ferreira, L, McHugh, K, Koekemoer, L, Draper, S.J.
Deposit date:2023-09-16
Release date:2024-07-31
Last modified:2024-09-18
Method:X-RAY DIFFRACTION (3.234 Å)
Cite:Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype.
Cell, 187, 2024
1UE2
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BU of 1ue2 by Molmil
Crystal structure of d(GC38GAAAGCT)
Descriptor: 5'-D(*GP*(C38)P*GP*AP*AP*AP*GP*CP*T)-3', CHLORIDE ION, COBALT HEXAMMINE(III), ...
Authors:Sunami, T, Kondo, J, Hirao, I, Watanaba, K, Miura, K, Takenaka, A.
Deposit date:2003-05-08
Release date:2004-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of d(GCGAAAGC) (hexagonal form): a base-intercalated duplex as a stable structure.
Acta Crystallogr.,Sect.D, 60, 2004
6XQW
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BU of 6xqw by Molmil
Crystal Structure of MaliM03 Fab in complex with Pfmsp1-19
Descriptor: MaliM03 Fab Heavy Chain, MaliM03 Fab Light Chain, Pfmsp1-19
Authors:Singh, S, Pancera, M.
Deposit date:2020-07-10
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.991 Å)
Cite:Multimeric antibodies from antigen-specific human IgM+ memory B cells restrict Plasmodium parasites.
J.Exp.Med., 218, 2021
1UE3
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BU of 1ue3 by Molmil
Crystal structure of d(GCGAAAGC) containing hexaamminecobalt
Descriptor: 5'-D(*GP*CP*GP*AP*AP*AP*GP*C)-3', CHLORIDE ION, COBALT HEXAMMINE(III), ...
Authors:Sunami, T, Kondo, J, Hirao, I, Watanabe, K, Miura, K, Takenaka, A.
Deposit date:2003-05-08
Release date:2004-01-13
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of d(GCGAAAGC) (hexagonal form): a base-intercalated duplex as a stable structure.
Acta Crystallogr.,Sect.D, 60, 2004
6H5N
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BU of 6h5n by Molmil
Plasmodium falciparum Pfs48/45 C-terminal domain bound to monoclonal antibody 85RF45.1
Descriptor: Antibody 85RF45.1 heavy chain, Antibody 85RF45.1 light chain, Gametocyte surface protein P45/48
Authors:Lennartz, F, Higgins, M.K.
Deposit date:2018-07-25
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody.
Nat Commun, 9, 2018
6PHF
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BU of 6phf by Molmil
Pfs25 in complex with the human transmission blocking antibody 2587
Descriptor: 25 kDa ookinete surface antigen, 2587 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHH
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BU of 6phh by Molmil
Unliganded human transmission blocking antibody 2544
Descriptor: 2544 Antibody Fab, Heavy Chain, Light Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHC
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BU of 6phc by Molmil
Pfs25 in complex with the human transmission blocking antibody 2544
Descriptor: 25 kDa ookinete surface antigen, 2544 Antibody Fab, Heavy Chain, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
6PHB
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BU of 6phb by Molmil
Pfs25 in complex with the human transmission blocking antibody 2530
Descriptor: 1,2-ETHANEDIOL, 25 kDa ookinete surface antigen, 2530 Antibody Fab, ...
Authors:McLeod, B.R, Julien, J.P.
Deposit date:2019-06-25
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Nat Commun, 10, 2019
2TLD
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BU of 2tld by Molmil
CRYSTAL STRUCTURE OF AN ENGINEERED SUBTILISIN INHIBITOR COMPLEXED WITH BOVINE TRYPSIN
Descriptor: STREPTOMYCES SUBTILISIN INHIBITOR (SSI), TRYPSIN
Authors:Mitsui, Y, Takeuchi, Y, Nonaka, T, Nakamura, K.T.
Deposit date:1991-09-16
Release date:1992-07-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of an engineered subtilisin inhibitor complexed with bovine trypsin.
Proc.Natl.Acad.Sci.USA, 89, 1992
5SIC
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BU of 5sic by Molmil
MOLECULAR RECOGNITION AT THE ACTIVE SITE OF SUBTILISIN BPN': CRYSTALLOGRAPHIC STUDIES USING GENETICALLY ENGINEERED PROTEINACEOUS INHIBITOR SSI (STREPTOMYCES SUBTILISIN INHIBITOR)
Descriptor: CALCIUM ION, SUBTILISIN BPN', SUBTILISIN INHIBITOR (SSI)
Authors:Mitsui, Y, Takeuchi, Y, Nakamura, K.T.
Deposit date:1991-11-18
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular recognition at the active site of subtilisin BPN': crystallographic studies using genetically engineered proteinaceous inhibitor SSI (Streptomyces subtilisin inhibitor).
Protein Eng., 4, 1991
1NGQ
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BU of 1ngq by Molmil
N1G9 (IGG1-LAMBDA) FAB FRAGMENT
Descriptor: N1G9 (IGG1-LAMBDA), SULFATE ION
Authors:Mizutani, R, Satow, Y.
Deposit date:1995-06-23
Release date:1996-07-11
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate.
J.Mol.Biol., 254, 1995
1NGP
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BU of 1ngp by Molmil
N1G9 (IGG1-LAMBDA) FAB FRAGMENT COMPLEXED WITH (4-HYDROXY-3-NITROPHENYL) ACETATE
Descriptor: 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID, N1G9 (IGG1-LAMBDA), SULFATE ION
Authors:Mizutani, R, Satow, Y.
Deposit date:1995-06-23
Release date:1996-07-11
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structures of the Fab fragment of murine N1G9 antibody from the primary immune response and of its complex with (4-hydroxy-3-nitrophenyl)acetate.
J.Mol.Biol., 254, 1995
3VJR
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BU of 3vjr by Molmil
Crystal structure of Peptidyl-tRNA hydrolase from Escherichia coli in complex with the CCA-acceptor-T[PSI]C domain of tRNA
Descriptor: Peptidyl-tRNA hydrolase, tRNA CCA-acceptor
Authors:Ito, K, Murakami, R, Mochizuki, M, Qi, H, Shimizu, Y, Miura, K.I, Ueda, T, Uchiumi, T.
Deposit date:2011-10-28
Release date:2012-09-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase.
Nucleic Acids Res., 40, 2012
8DFG
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BU of 8dfg by Molmil
Crystal structure of potently neutralizing human monoclonal antibody 42D6 Fab in complex with MSP1-19
Descriptor: 42D6 Fab Heavy Chain, 42D6 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFH
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BU of 8dfh by Molmil
Crystal structure of non-neutralizing / interfering human monoclonal antibody 42C3 Fab in complex with MSP1-19
Descriptor: 42C3 Fab Heavy Chain, 42C3 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFI
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BU of 8dfi by Molmil
Crystal structure of moderately neutralizing / interfering human monoclonal antibody 42C11 Fab in complex with MSP1-19
Descriptor: 42C11 Fab Heavy Chain, 42C11 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8EZL
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BU of 8ezl by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-50
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ...
Authors:Shukla, N, Tang, W.K, Tolia, N.H.
Deposit date:2022-11-01
Release date:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8EZM
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BU of 8ezm by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-63
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, SULFATE ION, ...
Authors:Shukla, N, Tang, W.K, Tolia, N.H.
Deposit date:2022-11-01
Release date:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8EZK
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BU of 8ezk by Molmil
Pfs25 in complex with transmission-reducing antibody AS01-04
Descriptor: 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-4, single-chain Fv
Authors:Shukla, N, Tang, W.K, Tolia, N.H.
Deposit date:2022-11-01
Release date:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
8GIF
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BU of 8gif by Molmil
Crystal structure of a designed single-component Plasmodium falciparum AMA1-RON2L insertion fusion immunogen 3
Descriptor: Apical membrane antigen 1, rhoptry neck protein 2 chimera
Authors:Patel, P.N, Tolia, N.H.
Deposit date:2023-03-14
Release date:2023-08-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based design of a strain transcending AMA1-RON2L malaria vaccine.
Nat Commun, 14, 2023
8GID
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BU of 8gid by Molmil
Crystal structure of a strain-transcending single-component Plasmodium falciparum AMA1-RON2L structure-based design immunogen 1 (SBD1)
Descriptor: Apical membrane antigen 1, rhoptry neck protein 2 chimera
Authors:Patel, P.N, Tolia, N.H.
Deposit date:2023-03-14
Release date:2023-08-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-based design of a strain transcending AMA1-RON2L malaria vaccine.
Nat Commun, 14, 2023
8GIE
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BU of 8gie by Molmil
Crystal structure of a designed single-component Plasmodium falciparum AMA1-RON2L insertion fusion immunogen 2
Descriptor: Apical membrane antigen 1, rhoptry neck protein 2 chimera
Authors:Patel, P.N, Tolia, N.H.
Deposit date:2023-03-14
Release date:2023-08-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure-based design of a strain transcending AMA1-RON2L malaria vaccine.
Nat Commun, 14, 2023
8G6B
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BU of 8g6b by Molmil
Crystal structure of PfAMA1-RON2L chimera
Descriptor: Apical membrane antigen 1, rhoptry neck protein 2 chimera, SULFATE ION
Authors:Boulanger, M.J, Ramaswamy, R.
Deposit date:2023-02-14
Release date:2023-09-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure guided mimicry of an essential P. falciparum receptor-ligand complex enhances cross neutralizing antibodies.
Nat Commun, 14, 2023

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