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1U0N
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BU of 1u0n by Molmil
The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex
Descriptor: Botrocetin, Platelet glycoprotein Ib, Von Willebrand factor
Authors:Fukuda, K, Liddington, R.C.
Deposit date:2004-07-13
Release date:2005-04-19
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation
Nat.Struct.Mol.Biol., 12, 2005
1U0O
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BU of 1u0o by Molmil
The mouse von Willebrand Factor A1-botrocetin complex
Descriptor: Botrocetin, von Willebrand factor
Authors:Fukuda, K, Liddington, R.C.
Deposit date:2004-07-14
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation
Nat.Struct.Mol.Biol., 12, 2005
1WVH
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BU of 1wvh by Molmil
Crystal structure of tensin1 PTB domain
Descriptor: Tensin
Authors:McCleverty, C.J, Liddington, R.C.
Deposit date:2004-12-15
Release date:2005-12-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the PTB domain of tensin1 and a model for its recruitment to fibrillar adhesions.
Protein Sci., 16, 2007
1YB0
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BU of 1yb0 by Molmil
Structure of PlyL
Descriptor: PHOSPHATE ION, ZINC ION, prophage LambdaBa02, ...
Authors:Low, L.Y, Yang, C, Perego, M, Osterman, A, Liddington, R.C.
Deposit date:2004-12-18
Release date:2005-08-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure and lytic activity of a Bacillus anthracis prophage endolysin
J.Biol.Chem., 280, 2005
1Y19
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Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1
Authors:de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C.
Deposit date:2004-11-17
Release date:2005-01-04
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
1I3O
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CRYSTAL STRUCTURE OF THE COMPLEX OF XIAP-BIR2 AND CASPASE 3
Descriptor: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, CASPASE 3, ZINC ION
Authors:Riedl, S.J, Renatus, M, Schwarzenbacher, R, Zhou, Q, Sun, C, Fesik, S.W, Liddington, R.C, Salvesen, G.S.
Deposit date:2001-02-15
Release date:2001-03-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the inhibition of caspase-3 by XIAP.
Cell(Cambridge,Mass.), 104, 2001
1J7N
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Anthrax Toxin Lethal factor
Descriptor: Lethal Factor precursor, SULFATE ION, ZINC ION
Authors:Pannifer, A.D, Wong, T.Y, Schwarzenbacher, R, Renatus, M, Petosa, C, Collier, R.J, Bienkowska, J, Lacy, D.B, Park, S, Leppla, S.H, Hanna, P, Liddington, R.C.
Deposit date:2001-05-17
Release date:2001-11-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1IJB
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The von Willebrand Factor mutant (I546V) A1 domain
Descriptor: von Willebrand factor
Authors:Fukuda, K, Doggett, T.A, Bankston, L.A, Cruz, M.A, Diacovo, T.G, Liddington, R.C.
Deposit date:2001-04-25
Release date:2002-07-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of von Willebrand factor activation by the snake toxin botrocetin.
Structure, 10, 2002
1JKY
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Crystal Structure of the Anthrax Lethal Factor (LF): Wild-type LF Complexed with the N-terminal Sequence of MAPKK2
Descriptor: Lethal Factor, mitogen-activated protein kinase kinase 2
Authors:Pannifer, A.D, Wong, T.Y, Schwarzenbacher, R, Renatus, M, Petosa, C, Collier, R.J, Bienkowska, J, Lacy, D.B, Park, S, Leppla, S.H, Hanna, P, Liddington, R.C.
Deposit date:2001-07-13
Release date:2001-11-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1JXQ
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Structure of cleaved, CARD domain deleted Caspase-9
Descriptor: Caspase-9, benzoxycarbonyl-Val-Ala-Asp-fluoromethyl ketone Inhibitor
Authors:Renatus, M, Stennicke, H.R, Scott, F.L, Liddington, R.C, Salvesen, G.S.
Deposit date:2001-09-08
Release date:2001-12-12
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dimer formation drives the activation of the cell death protease caspase 9.
Proc.Natl.Acad.Sci.USA, 98, 2001
1K40
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crystal structure of the FAT domain of focal adhesion kinase
Descriptor: adhesion kinase
Authors:Hayashi, I, Vuori, K, Liddington, R.C.
Deposit date:2001-10-04
Release date:2002-02-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin
Nat.Struct.Biol., 9, 2002
1MK7
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1MIX
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Crystal structure of a FERM domain of Talin
Descriptor: Talin
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MK9
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor: Integrin Beta3, TALIN
Authors:Garcia-Alvarez, B, De Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-28
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Determinants of Integrin Recognition by Talin
Mol.Cell, 11, 2003
1MIZ
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Crystal structure of an integrin beta3-talin chimera
Descriptor: TALIN, integrin beta3
Authors:Garcia-Alvarez, B, de Pereda, J.M, Calderwood, D.A, Ulmer, T.S, Critchley, D, Campbell, I.D, Ginsberg, M.H, Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MF7
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INTEGRIN ALPHA M I DOMAIN
Descriptor: INTEGRIN ALPHA M
Authors:McCleverty, C.J, Liddington, R.C.
Deposit date:2002-08-09
Release date:2003-05-20
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
1N9Z
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BU of 1n9z by Molmil
INTEGRIN ALPHA M I DOMAIN MUTANT
Descriptor: Integrin alpha-M, MAGNESIUM ION
Authors:McCleverty, C.J, Liddington, R.C.
Deposit date:2002-11-26
Release date:2003-05-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
1NA5
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BU of 1na5 by Molmil
INTEGRIN ALPHA M I DOMAIN
Descriptor: Integrin alpha-M
Authors:McCleverty, C.J, Liddington, R.C.
Deposit date:2002-11-26
Release date:2003-05-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Engineered allosteric mutants of the integrin alphaMbeta2 I domain: structural and functional studies
Biochem.J., 372, 2003
1OTW
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BU of 1otw by Molmil
Crystal structure of PqqC in complex with PQQ and a putative H2O2
Descriptor: Coenzyme PQQ synthesis protein C, HYDROGEN PEROXIDE, PYRROLOQUINOLINE QUINONE
Authors:Magnusson, O.T, Toyama, H, Saeki, M, Rojas, A, Reed, J.C, Liddington, R.C, Klinman, J.P, Schwarzenbacher, R.
Deposit date:2003-03-23
Release date:2004-05-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone.
Proc.Natl.Acad.Sci.USA, 101, 2004
1PWP
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Crystal Structure of the Anthrax Lethal Factor complexed with Small Molecule Inhibitor NSC 12155
Descriptor: Lethal factor, N,N'-BIS(4-AMINO-2-METHYLQUINOLIN-6-YL)UREA, ZINC ION
Authors:Wong, T.Y, Schwarzenbacher, R, Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-01-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification of small molecule inhibitors of anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
1PWQ
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Crystal structure of Anthrax Lethal Factor complexed with Thioacetyl-Tyr-Pro-Met-Amide, a metal-chelating peptidyl small molecule inhibitor
Descriptor: Lethal factor, N-(SULFANYLACETYL)TYROSYLPROLYLMETHIONINAMIDE, ZINC ION
Authors:Wong, T.Y, Schwarzenbacher, R, Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-01-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
1Q0P
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A domain of Factor B
Descriptor: Complement factor B, MANGANESE (II) ION
Authors:Bhattacharya, A.A, Liddington, R.C.
Deposit date:2003-07-17
Release date:2004-03-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the A Domain from Complement Factor B Reveals an Integrin-like Open Conformation.
STRUCTURE, 12, 2004
1PWW
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Crystal structure of Anthrax Lethal Factor active site mutant protein complexed with an optimised peptide substrate in the presence of zinc.
Descriptor: LF20, Lethal factor, ZINC ION
Authors:Wong, T.Y, Schwarzenbacher, R, Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
7KJZ
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BU of 7kjz by Molmil
crystal structure of PLEKHA7 PH domain biding inositol-tetraphosphate
Descriptor: 1,2-ETHANEDIOL, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Pleckstrin homology domain-containing family A member 7
Authors:Marassi, F.M, Aleshin, A.E, Liddington, R.C.
Deposit date:2020-10-26
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
Structure, 29, 2021
7KK7
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crystal structure of ligand-free PLEKHA7 PH domain
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Pleckstrin homology domain-containing family A member 7
Authors:Marassi, F.M, Aleshin, A.E, Liddington, R.C.
Deposit date:2020-10-27
Release date:2021-04-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
Structure, 29, 2021

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