1I3O

CRYSTAL STRUCTURE OF THE COMPLEX OF XIAP-BIR2 AND CASPASE 3

Summary for 1I3O

• Entry DOI: 10.2210/pdb1i3o/pdb
• Related: 1C9Q 1PAU
• Descriptor: CASPASE 3, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, ZINC ION, ... (5 entities in total)
• Functional Keywords: complex, iap, caspase, apoptosis
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P42574 P42574 P98170
• Total number of polymer chains: 6
• Total formula weight: 93536.04

Authors

Riedl, S.J.,Renatus, M.,Schwarzenbacher, R.,Zhou, Q.,Sun, C.,Fesik, S.W.,Liddington, R.C.,Salvesen, G.S. (deposition date: 2001-02-15, release date: 2001-03-21, Last modification date: 2023-08-09)

• Primary citation: Riedl, S.J.,Renatus, M.,Schwarzenbacher, R.,Zhou, Q.,Sun, C.,Fesik, S.W.,Liddington, R.C.,Salvesen, G.S.; Structural basis for the inhibition of caspase-3 by XIAP.; Cell(Cambridge,Mass.), 104:791-800, 2001; PubMed: 11257232; DOI: 10.1016/S0092-8674(01)00274-4

Experimental method

X-RAY DIFFRACTION (2.7 Å)