7NXP
 
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7NXQ
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4E4W
 | | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer | | Descriptor: | 1,2-ETHANEDIOL, DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, ... | | Authors: | Gueneau, E, Legrand, P, Charbonnier, J.B. | | Deposit date: | 2012-03-13 | | Release date: | 2013-02-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the MutLalpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
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4FMN
 | | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of NTG2 | | Descriptor: | 1,2-ETHANEDIOL, DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, ... | | Authors: | Gueneau, E, Legrand, P, Charbonnier, J.B. | | Deposit date: | 2012-06-18 | | Release date: | 2013-02-20 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
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4FMO
 | | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of exo1 | | Descriptor: | DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, DNA repair peptide, ... | | Authors: | Gueneau, E, Legrand, P, Charbonnier, J.B. | | Deposit date: | 2012-06-18 | | Release date: | 2013-02-20 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.04 Å) | | Cite: | Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
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3Q4F
 | | Crystal structure of xrcc4/xlf-cernunnos complex | | Descriptor: | DNA repair protein XRCC4, Non-homologous end-joining factor 1 | | Authors: | Ropars, V, Legrand, P, Charbonnier, J.B. | | Deposit date: | 2010-12-23 | | Release date: | 2011-08-03 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (5.5 Å) | | Cite: | Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2XUB
 | | Human RPC62 subunit structure | | Descriptor: | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 | | Authors: | Lefevre, S, Legrand, P, Fribourg, S. | | Deposit date: | 2010-10-18 | | Release date: | 2011-03-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure-Function Analysis of Hrpc62 Provides Insights Into RNA Polymerase III Transcription
Nat.Struct.Mol.Biol., 18, 2011
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1MRQ
 | | Crystal structure of human 20alpha-HSD in ternary complex with NADP and 20alpha-hydroxy-progesterone | | Descriptor: | Aldo-keto reductase family 1 member C1, BETA-MERCAPTOETHANOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Couture, J.F, Legrand, P, Cantin, L, Luu-The, V, Labrie, F, Breton, R. | | Deposit date: | 2002-09-18 | | Release date: | 2003-09-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids.
J.Mol.Biol., 331, 2003
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3CAO
 | | OXIDISED STRUCTURE OF THE ACIDIC CYTOCHROME C3 FROM DESULFOVIBRIO AFRICANUS | | Descriptor: | ARSENIC, CYTOCHROME C3, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Norager, S, Legrand, P, Pieulle, L, Hatchikian, C, Roth, M. | | Deposit date: | 1998-11-17 | | Release date: | 2000-07-23 | | Last modified: | 2018-04-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of the oxidised and reduced acidic cytochrome c3from Desulfovibrio africanus.
J.Mol.Biol., 290, 1999
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3CAR
 | | REDUCED STRUCTURE OF THE ACIDIC CYTOCHROME C3 FROM DESULFOVIBRIO AFRICANUS | | Descriptor: | ARSENIC, CYTOCHROME C3, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Norager, S, Legrand, P, Pieulle, L, Hatchikian, C, Roth, M. | | Deposit date: | 1998-11-17 | | Release date: | 2000-07-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the oxidised and reduced acidic cytochrome c3from Desulfovibrio africanus.
J.Mol.Biol., 290, 1999
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5AMS
 | | Crystal structure of Sqt1 | | Descriptor: | RIBOSOME ASSEMBLY PROTEIN SQT1 | | Authors: | Frenois, F, Legrand, P, Fribourg, S. | | Deposit date: | 2015-08-31 | | Release date: | 2016-01-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Sqt1P is an Eight-Bladed Wd40 Protein
Acta Crystallogr.,Sect.F, 72, 2016
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5OLL
 | | Crystal structure of gurmarin, a sweet taste suppressing polypeptide | | Descriptor: | Gurmarin, NICKEL (II) ION | | Authors: | Sigoillot, M, Neiers, F, Legrand, P, Roblin, P, Briand, L. | | Deposit date: | 2017-07-28 | | Release date: | 2018-08-08 | | Last modified: | 2019-02-20 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The Crystal Structure of Gurmarin, a Sweet Taste-Suppressing Protein: Identification of the Amino Acid Residues Essential for Inhibition.
Chem. Senses, 43, 2018
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6ERG
 | | Complex of XLF and heterodimer Ku bound to DNA | | Descriptor: | DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ... | | Authors: | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | | Deposit date: | 2017-10-18 | | Release date: | 2018-10-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
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6ERH
 | | Complex of XLF and heterodimer Ku bound to DNA | | Descriptor: | DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ... | | Authors: | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | | Deposit date: | 2017-10-18 | | Release date: | 2018-10-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
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6ERF
 | | Complex of APLF factor and Ku heterodimer bound to DNA | | Descriptor: | Aprataxin and PNK-like factor, DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ... | | Authors: | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | | Deposit date: | 2017-10-18 | | Release date: | 2018-10-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat.Struct.Mol.Biol., 25, 2018
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4HH6
 | | Peptide from EAEC T6SS Sci1 SciI protein | | Descriptor: | Peptide from EAEC T6SS Sci1 SciI protein, Putative type VI secretion protein | | Authors: | Douzi, B, Spinelli, S, Legrand, P, Lensi, V, Brunet, Y.R, Cascales, E, Cambillau, C. | | Deposit date: | 2012-10-09 | | Release date: | 2013-11-20 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Role and specificity of ClpV ATPases in T6SS secretion.
To be Published
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4HH5
 | | N-terminal domain (1-163) of ClpV1 ATPase from E.coli EAEC Sci1 T6SS. | | Descriptor: | BROMIDE ION, Putative type VI secretion protein | | Authors: | Douzi, B, Spinelli, S, Legrand, P, Lensi, V, Brunet, Y.R, Cascales, E, Cambillau, C. | | Deposit date: | 2012-10-09 | | Release date: | 2013-11-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Role and specificity of ClpV ATPases in T6SS secretion.
To be Published
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2V7F
 | | Structure of P. abyssi RPS19 protein | | Descriptor: | CHLORIDE ION, RPS19E SSU RIBOSOMAL PROTEIN S19E | | Authors: | Gregory, L.A, Aguissa-Toure, A.H, Pinaud, N, Legrand, P, Gleizes, P.E, Fribourg, S. | | Deposit date: | 2007-07-30 | | Release date: | 2007-09-11 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Molecular Basis of Diamond Blackfan Anemia: Structure and Function Analysis of Rps19.
Nucleic Acids Res., 35, 2007
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4A98
 | | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromoflurazepam | | Descriptor: | 7-BROMO-1-[2-(DIETHYLAMINO)ETHYL]-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE, CYS-LOOP LIGAND-GATED ION CHANNEL | | Authors: | Spurny, R, Brams, M, Nury, H, Legrand, P, Ulens, C. | | Deposit date: | 2011-11-24 | | Release date: | 2012-10-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.61 Å) | | Cite: | Pentameric Ligand-Gated Ion Channel Elic is Activated by Gaba and Modulated by Benzodiazepines.
Proc.Natl.Acad.Sci.USA, 109, 2012
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7QBT
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound. | | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CO-METHYLCOBALAMIN, FE (III) ION, ... | | Authors: | Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | Deposit date: | 2021-11-19 | | Release date: | 2022-02-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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7QBU
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound. | | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CO-METHYLCOBALAMIN, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | Deposit date: | 2021-11-19 | | Release date: | 2022-02-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.298 Å) | | Cite: | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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7QBS
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, S-adenosyl-L-methionine, and peptide bound. | | Descriptor: | CO-METHYLCOBALAMIN, FE (III) ION, IRON/SULFUR CLUSTER, ... | | Authors: | Bernardo-Garcia, N, Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | Deposit date: | 2021-11-19 | | Release date: | 2022-02-02 | | Last modified: | 2022-02-23 | | Method: | X-RAY DIFFRACTION (2.327 Å) | | Cite: | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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7QBV
 | | B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-adenosyl-L-homocysteine bound. | | Descriptor: | CO-METHYLCOBALAMIN, FE (III) ION, IRON/SULFUR CLUSTER, ... | | Authors: | Fyfe, C.D, Chavas, L.M.G, Legrand, P, Benjdia, A, Berteau, O. | | Deposit date: | 2021-11-19 | | Release date: | 2022-02-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.701 Å) | | Cite: | Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.
Nature, 602, 2022
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7QZ2
 | | Crystal structure of GacS D1 domain in complex with BeF3- | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, CADMIUM ION, Histidine kinase, ... | | Authors: | Fadel, F, Bassim, V, Botzanowski, T, Francis, V.I, Legrand, P, Porter, S.L, Bourne, Y, Cianferani, S, Vincent, F. | | Deposit date: | 2022-01-30 | | Release date: | 2022-07-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS.
Structure, 30, 2022
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7QZO
 | | Crystal structure of GacS D1 domain | | Descriptor: | CADMIUM ION, GLYCEROL, Histidine kinase | | Authors: | Fadel, F, Bassim, V, Botzanowski, T, Francis, V.I, Legrand, P, Porter, S.L, Bourne, Y, Cianferani, S, Vincent, F. | | Deposit date: | 2022-01-31 | | Release date: | 2022-07-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS.
Structure, 30, 2022
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