6E1K
| Structure of AtTPC1(DDE) reconstituted in saposin A with cat06 Fab | Descriptor: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ... | Authors: | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | Deposit date: | 2018-07-10 | Release date: | 2018-09-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6VI1
| Structure of Fab4 bound to P22 TerL(1-33) | Descriptor: | Synthetic Fab4 heavy chain, Synthetic Fab4 light chain, Terminase, ... | Authors: | Cingolani, G, Lokareddy, R, Ko, Y. | Deposit date: | 2020-01-11 | Release date: | 2020-09-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment. Acta Crystallogr D Struct Biol, 76, 2020
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6VI2
| Structure of the unaligned Fab4 | Descriptor: | FAB4 heavy chain, FAB4 light chain | Authors: | Cingolani, G, Lokareddy, R, Ko, Y. | Deposit date: | 2020-01-11 | Release date: | 2020-09-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment. Acta Crystallogr D Struct Biol, 76, 2020
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6WW2
| Structure of human Frizzled5 by fiducial-assisted cryo-EM | Descriptor: | Frizzled-5,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ... | Authors: | Tsutsumi, N, Jude, K.M, Gati, C, Garcia, K.C. | Deposit date: | 2020-05-07 | Release date: | 2020-08-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling. Elife, 9, 2020
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6XMI
| Structure of Fab4 bound to P22 TerL(1-33) | Descriptor: | Fab Heavy chain, Fab Light chain, Terminase, ... | Authors: | Cingolani, G, Lokareddy, R, Ko, Y. | Deposit date: | 2020-06-30 | Release date: | 2020-08-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment. Acta Crystallogr D Struct Biol, 76, 2020
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1NAG
| CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A | Descriptor: | BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION | Authors: | Danishefsky, A.T, Wlodawer, A, Kim, K.-S, Tao, F, Woodward, C. | Deposit date: | 1992-08-18 | Release date: | 1993-10-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A. Protein Sci., 2, 1993
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1FAN
| CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A | Descriptor: | BOVINE PANCREATIC TRYPSIN INHIBITOR | Authors: | Danishefsky, A.T, Wlodawer, A, Kim, K.-S, Tao, F, Woodward, C. | Deposit date: | 1992-08-21 | Release date: | 1993-10-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A. Protein Sci., 2, 1993
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1AXI
| STRUCTURAL PLASTICITY AT THE HGH:HGHBP INTERFACE | Descriptor: | GROWTH HORMONE, GROWTH HORMONE RECEPTOR, SULFATE ION | Authors: | Atwell, S, Ultsch, M, De Vos, A.M, Wells, J.A. | Deposit date: | 1997-10-15 | Release date: | 1998-01-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural plasticity in a remodeled protein-protein interface. Science, 278, 1997
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5WOB
| Crystal Structure Analysis of Fab1-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin | Descriptor: | IDE-bound Fab heavy chain, IDE-bound Fab light chain, Insulin, ... | Authors: | McCord, L.A, Liang, W.G, Farcasanu, M, Wang, A.G, Koide, S, Tang, W.J. | Deposit date: | 2017-08-01 | Release date: | 2018-04-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.95 Å) | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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4I18
| Crystal structure of human prolactin receptor complexed with Fab fragment | Descriptor: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | Authors: | Duguid, E.M, Mukherjee, S, Kouadio, J.L. | Deposit date: | 2012-11-20 | Release date: | 2013-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.238 Å) | Cite: | Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling. Cell Commun Signal, 13, 2015
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4JQ5
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4JNV
| Crystal structure of the human Nup57CCS3* coiled-coil segment, space group C2 | Descriptor: | Nucleoporin p54 | Authors: | Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. | Deposit date: | 2013-03-15 | Release date: | 2014-09-17 | Last modified: | 2016-02-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015
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4JNU
| Crystal structure of the human Nup57CCS3* coiled-coil segment, space group P21 | Descriptor: | Nucleoporin p54 | Authors: | Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. | Deposit date: | 2013-03-15 | Release date: | 2014-09-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.445 Å) | Cite: | Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015
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4JO9
| Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex 1:2 stoichiometry | Descriptor: | Nucleoporin p54, Nucleoporin p58/p45 | Authors: | Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. | Deposit date: | 2013-03-18 | Release date: | 2014-09-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015
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4JO7
| Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex with 2:2 stoichiometry | Descriptor: | Nucleoporin p54, Nucleoporin p58/p45 | Authors: | Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. | Deposit date: | 2013-03-17 | Release date: | 2014-09-17 | Last modified: | 2016-02-03 | Method: | X-RAY DIFFRACTION (1.752 Å) | Cite: | Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015
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7MDJ
| The structure of KcsA in complex with a synthetic Fab | Descriptor: | Fab heavy chain, Fab light chain, POTASSIUM ION, ... | Authors: | Rohaim, A, Slezak, T, Blackowicz, L, Kossiakoff, A, Roux, B. | Deposit date: | 2021-04-05 | Release date: | 2022-02-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels. J.Gen.Physiol., 154, 2022
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7PGI
| NaVAb1p (bicelles) | Descriptor: | ACETATE ION, Ion transport protein, MAGNESIUM ION, ... | Authors: | Lolicato, M, Arrigoni, C. | Deposit date: | 2021-08-14 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.638 Å) | Cite: | Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29, 2022
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7PGF
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7PG8
| NaV_Ae1/Sp1CTD_pore-ANT05 complex | Descriptor: | ANT05 H12 fab fragment, heavy chain, light chain, ... | Authors: | Lolicato, M, Arrigoni, C. | Deposit date: | 2021-08-13 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29, 2022
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7PGB
| NaV_Ae1/Sp1CTD_pore-SAT09 complex | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-NITROBENZOIC ACID, ... | Authors: | Lolicato, M, Arrigoni, C. | Deposit date: | 2021-08-13 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29, 2022
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7PGG
| NaVAb1p detergent (DM) | Descriptor: | 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, Ion transport protein | Authors: | Lolicato, M, Arrigoni, C. | Deposit date: | 2021-08-13 | Release date: | 2022-06-15 | Last modified: | 2022-06-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29, 2022
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7PGH
| NaVAe1/Sp1CTDp (DDM) | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DODECAETHYLENE GLYCOL, DODECANE, ... | Authors: | Lolicato, M, Arrigoni, C. | Deposit date: | 2021-08-14 | Release date: | 2022-06-15 | Last modified: | 2022-06-29 | Method: | X-RAY DIFFRACTION (4.194 Å) | Cite: | Quaternary structure independent folding of voltage-gated ion channel pore domain subunits. Nat.Struct.Mol.Biol., 29, 2022
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7RU6
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7RUG
| Human SERINC3-DeltaICL4 | Descriptor: | Serine incorporator 3, SiA | Authors: | Purdy, M.D, Leonhardt, S.A, Yeager, M. | Deposit date: | 2021-08-17 | Release date: | 2022-08-24 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry. Nat Commun, 14, 2023
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7SK9
| Cryo-EM structure of human ACKR3 in complex with a small molecule partial agonist CCX662, and an intracellular Fab | Descriptor: | (1R)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium, Atypical chemokine receptor 3, CHOLESTEROL, ... | Authors: | Yen, Y.C, Schafer, C.T, Gustavsson, M, Handel, T.M, Tesmer, J.J.G. | Deposit date: | 2021-10-19 | Release date: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv, 8, 2022
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