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4C0F
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BU of 4c0f by Molmil
Structure of the NOT-box domain of human CNOT2
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2
著者Boland, A, Chen, Y, Raisch, T, Jonas, S, Izaurralde, E, Weichenrieder, O.
登録日2013-08-01
公開日2013-10-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and Assembly of the not Module of the Human Ccr4-not Complex
Nat.Struct.Mol.Biol., 20, 2013
4CRV
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BU of 4crv by Molmil
Complex of human CNOT9 and CNOT1 including two tryptophans
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL, ...
著者Boland, A, Chen, Y, Izaurralde, E, Weichenrieder, O.
登録日2014-03-01
公開日2014-05-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014
4CRU
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BU of 4cru by Molmil
Complex of human CNOT9 and CNOT1 including one tryptophan
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL
著者Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O.
登録日2014-03-01
公開日2014-05-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014
4CQO
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BU of 4cqo by Molmil
Structure of the human CNOT1 superfamily homology domain in complex with a Nanos1 peptide
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, NANOS HOMOLOG 1
著者Raisch, T, Jonas, S, Weichenrieder, O, Bhandari, D, Izaurralde, E.
登録日2014-02-21
公開日2014-04-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Nanos-Mediated Recruitment of the Ccr4-not Complex and Translational Repression
Genes Dev., 28, 2014
4CRW
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BU of 4crw by Molmil
Complex of human DDX6 (RECA-C) and CNOT1 (MIF4G)
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, GLYCEROL, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6
著者Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O.
登録日2014-03-01
公開日2014-05-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014
7AX1
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BU of 7ax1 by Molmil
Crystal structure of the human CCR4-CAF1 complex
分子名称: CCR4-NOT transcription complex subunit 6, CCR4-NOT transcription complex subunit 7, MAGNESIUM ION
著者Chen, Y, Khazina, E, Weichenrieder, O.
登録日2020-11-09
公開日2021-05-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex.
Nucleic Acids Res., 49, 2021
6S8R
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BU of 6s8r by Molmil
D. melanogaster RNA helicase Me31B in complex with GIGYF
分子名称: ACETATE ION, ATP-dependent RNA helicase me31b, GIGYF family protein CG11148
著者Peter, D, Valkov, E.
登録日2019-07-10
公開日2019-09-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.
Genes Dev., 33, 2019
6S8S
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BU of 6s8s by Molmil
Extended structure of the human DDX6 C-terminal domain in complex with an EDC3 FDF peptide
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Enhancer of mRNA-decapping protein 3, PHOSPHATE ION, ...
著者Peter, D, Valkov, E.
登録日2019-07-10
公開日2019-09-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Molecular basis for GIGYF-Me31B complex assembly in 4EHP-mediated translational repression.
Genes Dev., 33, 2019
6FC2
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BU of 6fc2 by Molmil
Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae
分子名称: CALCIUM ION, Eukaryotic translation initiation factor 4E, Protein EAP1
著者Gruener, S, Valkov, E.
登録日2017-12-20
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FBZ
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BU of 6fbz by Molmil
Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum in the cap-bound state
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-like protein,Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G
著者Gruener, S, Valkov, E.
登録日2017-12-20
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.496 Å)
主引用文献Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC3
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BU of 6fc3 by Molmil
Crystal structure of the eIF4E-p20 complex from Saccharomyces cerevisiae
分子名称: Cap-associated protein CAF20, Eukaryotic translation initiation factor 4E, GLYCEROL, ...
著者Gruener, S, Valkov, E.
登録日2017-12-20
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC1
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BU of 6fc1 by Molmil
Crystal structure of the eIF4E-Eap1p complex from Saccharomyces cerevisiae in the cap-bound state
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, GLYCEROL, ...
著者Gruener, S, Valkov, E.
登録日2017-12-20
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
6FC0
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BU of 6fc0 by Molmil
Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum
分子名称: Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G
著者Gruener, S, Valkov, E.
登録日2017-12-20
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.293 Å)
主引用文献Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.
Nucleic Acids Res., 46, 2018
4UE8
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BU of 4ue8 by Molmil
Complex of D. melanogaster eIF4E with the 4E binding protein Thor
分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 4E-BINDING PROTEIN THOR, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, ...
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UEB
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BU of 4ueb by Molmil
Complex of D. melanogaster eIF4E with a designed 4E-binding protein (Form II)
分子名称: DESIGNED 4E-BP, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UED
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BU of 4ued by Molmil
Complex of human eIF4E with the 4E binding protein 4E-BP1
分子名称: EUKARYOTIC TRANSLATION FACTOR 4E-BINDING PROTEIN 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UEA
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BU of 4uea by Molmil
Complex of D. melanogaster eIF4E with a designed 4E-binding protein (Form I)
分子名称: DESIGNED 4E-BP, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UE9
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BU of 4ue9 by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein 4E-T
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UEC
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BU of 4uec by Molmil
Complex of D. melanogaster eIF4E with eIF4G and cap analog
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, ...
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
2LYD
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BU of 2lyd by Molmil
The solution structure of the Dm DCP1 EVH1 domain in complex with the XRN1 DBM peptide
分子名称: Decapping protein 1, Pacman protein
著者Truffault, V.
登録日2012-09-17
公開日2012-10-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation.
Nat.Struct.Mol.Biol., 19, 2012
2YHA
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BU of 2yha by Molmil
Crystal Structure of the N. crassa QDE-2 AGO MID-PIWI Domains
分子名称: GLYCEROL, POST-TRANSCRIPTIONAL GENE SILENCING PROTEIN QDE-2, SULFATE ION
著者Boland, A, Weichenrieder, O.
登録日2011-04-27
公開日2011-06-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of the Mid-Piwi Lobe of a Eukaryotic Argonaute Protein
Proc.Natl.Acad.Sci.USA, 108, 2011
2YHB
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BU of 2yhb by Molmil
Crystal Structure of the N. crassa QDE-2 AGO MID-PIWI Domains
分子名称: GLYCEROL, POST-TRANSCRIPTIONAL GENE SILENCING PROTEIN QDE-2, SULFATE ION
著者Boland, A, Weichenrieder, O.
登録日2011-04-27
公開日2011-06-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Crystal Structure of the Mid-Piwi Lobe of a Eukaryotic Argonaute Protein
Proc.Natl.Acad.Sci.USA, 108, 2011
5NVN
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BU of 5nvn by Molmil
Crystal structure of the human 4EHP-4E-BP1 complex
分子名称: Eukaryotic translation initiation factor 4E type 2, Eukaryotic translation initiation factor 4E-binding protein 1, FORMIC ACID
著者Peter, D, Sandmeir, F, Valkov, E.
登録日2017-05-04
公開日2017-07-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
Genes Dev., 31, 2017
5NVM
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BU of 5nvm by Molmil
Crystal structure of the human 4EHP-GIGYF2 complex lacking the auxiliary sequences
分子名称: Eukaryotic translation initiation factor 4E type 2, GRB10-interacting GYF protein 2, PHOSPHATE ION
著者Peter, D, Valkov, E.
登録日2017-05-04
公開日2017-07-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
Genes Dev., 31, 2017
5NVK
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BU of 5nvk by Molmil
Crystal structure of the human 4EHP-GIGYF1 complex
分子名称: Eukaryotic translation initiation factor 4E type 2, GRB10-interacting GYF protein 1
著者Peter, D, Valkov, E.
登録日2017-05-04
公開日2017-07-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
Genes Dev., 31, 2017

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