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5FU7
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drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ...
著者Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E.
登録日2016-01-21
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
5FU6
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BU of 5fu6 by Molmil
NOT module of the human CCR4-NOT complex (Crystallization mutant)
分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3
著者Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E.
登録日2016-01-21
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
5LSW
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BU of 5lsw by Molmil
A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell differentiation protein RCD1 homolog, LD12033p, ...
著者Sgromo, A, Raisch, T, Bawankar, P, Bhandari, D, Chen, Y, Kuzuoglu-Ozturk, D, Weichenrieder, O, Izaurralde, E.
登録日2016-09-05
公開日2017-02-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin.
Nat Commun, 8, 2017
1FT8
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BU of 1ft8 by Molmil
CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE MRNA EXPORT FACTOR TAP
分子名称: TIP ASSOCIATING PROTEIN
著者Liker, E, Fernandez, E, Izaurralde, E, Conti, E.
登録日2000-09-12
公開日2000-12-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain.
EMBO J., 19, 2000
1FO1
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BU of 1fo1 by Molmil
CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE MRNA EXPORT FACTOR TAP
分子名称: NUCLEAR RNA EXPORT FACTOR 1
著者Liker, E, Fernandez, E, Izaurralde, E, Conti, E.
登録日2000-08-24
公開日2000-11-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain.
EMBO J., 19, 2000
2B9Z
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BU of 2b9z by Molmil
Solution structure of FHV B2, a viral suppressor of RNAi
分子名称: B2 protein
著者Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
登録日2005-10-13
公開日2005-11-29
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.
Embo Rep., 6, 2005
4GMJ
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BU of 4gmj by Molmil
Structure of human NOT1 MIF4G domain co-crystallized with CAF1
分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ...
著者Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
4GML
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BU of 4gml by Molmil
Crystal structure of human NOT1 MIF4G domain
分子名称: CCR4-NOT transcription complex subunit 1
著者Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
5T47
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BU of 5t47 by Molmil
Crystal structure of the D. melanogaster eIF4E-eIF4G complex
分子名称: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, isoform A, ...
著者Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
登録日2016-08-29
公開日2016-10-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5J3T
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BU of 5j3t by Molmil
Crystal structure of S. pombe Dcp2:Dcp1:Edc1 mRNA decapping complex
分子名称: Edc1, FORMIC ACID, MAGNESIUM ION, ...
著者Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
登録日2016-03-31
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5J3Q
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BU of 5j3q by Molmil
Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex
分子名称: Edc1, mRNA-decapping enzyme subunit 1
著者Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
登録日2016-03-31
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
5T46
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BU of 5t46 by Molmil
Crystal structure of the human eIF4E-eIF4G complex
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, ...
著者Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
登録日2016-08-29
公開日2016-10-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5T48
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BU of 5t48 by Molmil
Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, ...
著者Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
登録日2016-08-29
公開日2016-10-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5J3Y
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BU of 5j3y by Molmil
Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex
分子名称: mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1
著者Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E.
登録日2016-03-31
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.288 Å)
主引用文献Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
6H3Z
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BU of 6h3z by Molmil
Crystal structure of a C-terminal MIF4G domain in NOT1
分子名称: CCR4-not transcription complex subunit 1, SODIUM ION
著者Raisch, T, Sandmeir, F, Weichenrieder, O, Valkov, E, Izaurralde, E.
登録日2018-07-19
公開日2018-11-07
最終更新日2018-12-26
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex.
J. Struct. Biol., 204, 2018
1W3B
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BU of 1w3b by Molmil
The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
分子名称: CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110
著者Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E.
登録日2004-07-14
公開日2004-09-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
1T2R
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BU of 1t2r by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
分子名称: 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2
著者Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
登録日2004-04-22
公開日2004-06-01
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1YA0
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BU of 1ya0 by Molmil
Crystal structure of the N-terminal domain of human SMG7
分子名称: SMG-7 transcript variant 2, SULFATE ION
著者Fukuhara, N, Ebert, J, Unterholzner, L, Lindner, D, Izaurralde, E, Conti, E.
登録日2004-12-17
公開日2005-03-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献SMG7 Is a 14-3-3-like Adaptor in the Nonsense-Mediated mRNA Decay Pathway.
Mol.Cell, 17, 2005
1T2S
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BU of 1t2s by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
分子名称: 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2
著者Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
登録日2004-04-22
公開日2004-06-01
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
3RW6
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BU of 3rw6 by Molmil
Structure of nuclear RNA export factor TAP bound to CTE RNA
分子名称: Nuclear RNA export factor 1, constitutive transport element(CTE)of Mason-Pfizer monkey virus RNA
著者Teplova, M, Khin, N.W, Patel, D.J, Izaurralde, E.
登録日2011-05-07
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
Nat.Struct.Mol.Biol., 18, 2011
3RW7
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BU of 3rw7 by Molmil
Structure of N-terminal domain of nuclear RNA export factor TAP
分子名称: Nuclear RNA export factor 1
著者Teplova, M, Khin, N.W, Wohlbold, L, Izaurralde, E, Patel, D.J.
登録日2011-05-07
公開日2011-08-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
Nat.Struct.Mol.Biol., 18, 2011
3ZHE
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BU of 3zhe by Molmil
Structure of the C. elegans SMG5-SMG7 complex
分子名称: NONSENSE-MEDIATED MRNA DECAY PROTEIN, PROTEIN SMG-7
著者Jonas, S, Weichenrieder, O, Izaurralde, E.
登録日2012-12-21
公開日2013-02-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献An Unusual Arrangement of Two 14-3-3-Like Domains in the Smg5-Smg7 Heterodimer is Required for Efficient Nonsense-Mediated Mrna Decay.
Genes Dev., 27, 2013
4A54
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Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6
分子名称: EDC3, MRNA DECAPPING COMPLEX SUBUNIT 2
著者Fromm, S.A, Truffault, V, Kamenz, J, Braun, J.E, Hoffmann, N.A, Izaurralde, E, Sprangers, R.
登録日2011-10-24
公開日2012-02-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Structural Basis of Edc3- and Scd6-Mediated Activation of the Dcp1:Dcp2 Mrna Decapping Complex.
Embo J., 31, 2011
2HWX
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BU of 2hwx by Molmil
Structure of human SMG6 E1282C PIN domain mutant.
分子名称: Telomerase-binding protein EST1A
著者Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E.
登録日2006-08-02
公開日2006-11-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
Embo J., 25, 2006
2HWW
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BU of 2hww by Molmil
Structure of PIN domain of human SMG6
分子名称: Telomerase-binding protein EST1A
著者Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E.
登録日2006-08-02
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.
Embo J., 25, 2006

 

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