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6DFF
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BU of 6dff by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H.
Deposit date:2018-05-14
Release date:2018-08-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
6D83
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BU of 6d83 by Molmil
Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric subunit
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Buffalo, C.Z, Morris, K.L, Hurley, J.H.
Deposit date:2018-04-25
Release date:2018-08-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.27 Å)
Cite:HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation.
Cell, 174, 2018
2PJW
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BU of 2pjw by Molmil
The Vps27/Hse1 complex is a GAT domain-based scaffold for ubiquitin-dependent sorting
Descriptor: Uncharacterized protein YHL002W, Vacuolar protein sorting-associated protein 27
Authors:Prag, G, Hurley, J.H.
Deposit date:2007-04-16
Release date:2007-06-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:The Vps27/Hse1 Complex Is a GAT Domain-Based Scaffold for Ubiquitin-Dependent Sorting.
Dev.Cell, 12, 2007
2F6M
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BU of 2f6m by Molmil
Structure of a Vps23-C:Vps28-N subcomplex
Descriptor: DECYLAMINE-N,N-DIMETHYL-N-OXIDE, MAGNESIUM ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ...
Authors:Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H.
Deposit date:2005-11-29
Release date:2006-04-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional organization of the ESCRT-I trafficking complex.
Cell(Cambridge,Mass.), 125, 2006
2FAU
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BU of 2fau by Molmil
Crystal structure of human vps26
Descriptor: GLYCEROL, Vacuolar protein sorting 26
Authors:Shi, H, Rojas, R, Bonifacino, J.S, Hurley, J.H.
Deposit date:2005-12-08
Release date:2006-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain.
Nat.Struct.Mol.Biol., 13, 2006
2FID
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BU of 2fid by Molmil
Crystal Structure of a Bovine Rabex-5 fragment complexed with ubiquitin
Descriptor: Rab5 GDP/GTP exchange factor, Ubiquitin, ZINC ION
Authors:Lee, S, Hurley, J.H.
Deposit date:2005-12-29
Release date:2006-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
Nat.Struct.Mol.Biol., 13, 2006
2F66
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BU of 2f66 by Molmil
Structure of the ESCRT-I endosomal trafficking complex
Descriptor: Protein SRN2, SULFATE ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ...
Authors:Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H.
Deposit date:2005-11-28
Release date:2006-04-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and functional organization of the ESCRT-I trafficking complex.
Cell(Cambridge,Mass.), 125, 2006
2FIF
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BU of 2fif by Molmil
Crystal Structure of a Bovine Rabex-5 fragment complexed with ubiquitin
Descriptor: Rab5 GDP/GTP exchange factor, SULFATE ION, Ubiquitin, ...
Authors:Lee, S, Hurley, J.H.
Deposit date:2005-12-29
Release date:2006-02-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
Nat.Struct.Mol.Biol., 13, 2006
8D9W
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BU of 8d9w by Molmil
beta-Arf1 homodimeric interface within AP-1, Arf1, Nef, MHC-I lattice on narrow tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.H, Hurley, J.H.
Deposit date:2022-06-11
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8DHB
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BU of 8dhb by Molmil
Active FLCN GAP complex
Descriptor: BERYLLIUM TRIFLUORIDE ION, Folliculin, Folliculin-interacting protein 2, ...
Authors:Jansen, R.M, Hurley, J.H.
Deposit date:2022-06-25
Release date:2022-09-28
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation.
Sci Adv, 8, 2022
3CUQ
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BU of 3cuq by Molmil
Integrated structural and functional model of the human ESCRT-II complex
Descriptor: Vacuolar protein-sorting-associated protein 25, Vacuolar protein-sorting-associated protein 36, Vacuolar-sorting protein SNF8
Authors:Im, Y.J, Hurley, J.H.
Deposit date:2008-04-16
Release date:2008-11-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Integrated structural model and membrane targeting mechanism of the human ESCRT-II complex
Dev.Cell, 14, 2008
8D9V
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BU of 8d9v by Molmil
gamma-Arf1 homodimeric interface within AP-1, Arf1, Nef lattice on narrow membrane tubes
Descriptor: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9S
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BU of 8d9s by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on beta-Arf1
Descriptor: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9T
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BU of 8d9t by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on gamma-Arf1
Descriptor: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9R
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BU of 8d9r by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on gamma-Arf1
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9U
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BU of 8d9u by Molmil
AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on beta-Arf1
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8DO8
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BU of 8do8 by Molmil
Crystal structure ATG9 HDIR in complex with the ATG13:ATG101 HORMA dimer
Descriptor: Autophagy-related protein 101, Autophagy-related protein 13, GLYCEROL
Authors:Buffalo, C.Z, Ren, X, Yokom, A.L, Hurley, J.H.
Deposit date:2022-07-12
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation.
Sci Adv, 9, 2023
8D4G
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BU of 8d4g by Molmil
gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-01
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (11.6 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D4C
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BU of 8d4c by Molmil
beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-01
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D4E
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BU of 8d4e by Molmil
Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-01
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D4F
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BU of 8d4f by Molmil
beta-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-01
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D4D
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BU of 8d4d by Molmil
gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide incorporated narrow membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-01
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (9.6 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
3E1R
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BU of 3e1r by Molmil
Midbody targeting of the ESCRT machinery by a non-canonical coiled-coil in CEP55
Descriptor: Centrosomal protein of 55 kDa, Programmed cell death 6-interacting protein
Authors:Lee, H.H, Elia, N, Ghirlando, R, Lippincott-Schwartz, J, Hurley, J.H.
Deposit date:2008-08-04
Release date:2008-11-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55.
Science, 322, 2008
3EAB
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BU of 3eab by Molmil
Crystal structure of Spastin MIT in complex with ESCRT III
Descriptor: CHMP1b, Spastin
Authors:Yang, D, Rimanchi, N, Renvoise, B, Lippincott-Schwartz, J, Blackstone, C, Hurley, J.H.
Deposit date:2008-08-25
Release date:2008-11-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B.
Nat.Struct.Mol.Biol., 15, 2008
3F1I
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BU of 3f1i by Molmil
Human ESCRT-0 Core Complex
Descriptor: Hepatocyte growth factor-regulated tyrosine kinase substrate, Signal transducing adapter molecule 1
Authors:Ren, X, Kloer, D.P, Kim, Y, Ghirlando, R, Saidi, L, Hummer, G, Hurley, J.H.
Deposit date:2008-10-28
Release date:2009-03-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Hybrid Structural Model of the Complete Human ESCRT-0 Complex.
Structure, 17, 2009

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