2W3C
 
 | | Globular head region of the human general vesicular transport factor p115 | | Descriptor: | DI(HYDROXYETHYL)ETHER, GENERAL VESICULAR TRANSPORT FACTOR P115 | | Authors: | Striegl, H, Roske, Y, Kummel, D, Heinemann, U. | | Deposit date: | 2008-11-11 | | Release date: | 2009-03-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Unusual Armadillo Fold in the Human General Vesicular Transport Factor P115
Plos One, 4, 2009
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2WBS
 | | Crystal structure of the zinc finger domain of Klf4 bound to its target DNA | | Descriptor: | 5'-D(*GP*AP*GP*GP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*CP*CP*TP*CP)-3', GLYCEROL, ... | | Authors: | Zocher, G, Schuetz, A, Carstanjen, D, Heinemann, U. | | Deposit date: | 2009-03-03 | | Release date: | 2010-04-07 | | Last modified: | 2011-10-05 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.
Cell.Mol.Life Sci., 68, 2011
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2WBU
 | | CRYSTAL STRUCTURE OF THE ZINC FINGER DOMAIN OF KLF4 BOUND TO ITS TARGET DNA | | Descriptor: | 5'-D(*DGP*DAP*DGP*DGP*DCP*DGP*DTP* DGP*DGP*DC)-3', 5'-D(*DGP*DCP*DCP*DAP*DCP*DGP*DCP* DCP*DTP*DC)-3', KRUEPPEL-LIKE FACTOR 4, ... | | Authors: | Schuetz, A, Zocher, G, Carstanjen, D, Heinemann, U. | | Deposit date: | 2009-03-05 | | Release date: | 2010-04-07 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.
Cell.Mol.Life Sci., 68, 2011
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2VNL
 | | MUTANT Y108Wdel OF THE HEADBINDING DOMAIN OF PHAGE P22 TAILSPIKE C- TERMINally fused to ISOLEUCINE ZIPPER pIIGCN4 (chimera II) | | Descriptor: | BIFUNCTIONAL TAIL PROTEIN, PIIGCN4, GLYCEROL | | Authors: | Mueller, J.J, Seul, A, Mueller, G, Seckler, R, Heinemann, U. | | Deposit date: | 2008-02-05 | | Release date: | 2009-02-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Bacteriophage P22 Tailspike: Structure of the Complete Protein and Function of the Interdomain Linker
Acta Crystallogr.,Sect.D, 70, 2014
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2WNH
 | | Crystal Structure Analysis of Klebsiella sp ASR1 Phytase | | Descriptor: | 3-PHYTASE, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Bohm, K, Mueller, J.J, Heinemann, U. | | Deposit date: | 2009-07-09 | | Release date: | 2010-04-28 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Crystal Structure of Klebsiella Sp. Asr1 Phytase Suggests Substrate Binding to a Preformed Active Site that Meets the Requirements of a Plant Rhizosphere Enzyme.
FEBS J., 277, 2010
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2WLB
 | | Adrenodoxin-like ferredoxin Etp1fd(516-618) of Schizosaccharomyces pombe mitochondria | | Descriptor: | ELECTRON TRANSFER PROTEIN 1, MITOCHONDRIAL, FE2/S2 (INORGANIC) CLUSTER | | Authors: | Mueller, J.J, Hannemann, F, Schiffler, B, Bernhardt, R, Heinemann, U. | | Deposit date: | 2009-06-23 | | Release date: | 2010-08-25 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and Thermodynamic Characterization of the Adrenodoxin-Like Domain of the Electron-Transfer Protein Etp1 from Schizosaccharomyces Pombe.
J.Inorg.Biochem., 105, 2011
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2WNI
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2WU0
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2XC1
 | | Full-length Tailspike Protein Mutant Y108W of Bacteriophage P22 | | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, BIFUNCTIONAL TAIL PROTEIN, CALCIUM ION, ... | | Authors: | Mueller, J.J, Seul, A, Seckler, R, Heinemann, U. | | Deposit date: | 2010-04-15 | | Release date: | 2011-05-04 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Bacteriophage P22 Tailspike: Structure of the Complete Protein and Function of the Interdomain Linker
Acta Crystallogr.,Sect.D, 70, 2014
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2YMA
 | | X-ray structure of the Yos9 dimerization domain | | Descriptor: | PROTEIN OS-9 HOMOLOG | | Authors: | Hanna, J, Schuetz, A, Zimmermann, F, Behlke, J, Sommer, T, Heinemann, U. | | Deposit date: | 2011-06-07 | | Release date: | 2012-01-25 | | Last modified: | 2012-03-28 | | Method: | X-RAY DIFFRACTION (2.545 Å) | | Cite: | Structural and Biochemical Basis of Yos9 Protein Dimerization and Possible Contribution to Self-Association of 3-Hydroxy-3-Methylglutaryl-Coenzyme a Reductase Degradation Ubiquitin-Ligase Complex.
J.Biol.Chem., 287, 2012
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2YIL
 | | Crystal Structure of Parasite Sarcocystis muris Lectin SML-2 | | Descriptor: | CHLORIDE ION, GLYCEROL, MICRONEME ANTIGEN L2, ... | | Authors: | Mueller, J.J, Weiss, M.S, Heinemann, U. | | Deposit date: | 2011-05-16 | | Release date: | 2011-11-02 | | Last modified: | 2019-07-17 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Pan-Modular Structure of Microneme Protein Sml-2 from Parasite Sarcocystis Muris at 1.95 A Resolution and its Complex with 1-Thio-Beta-D-Galactose.
Acta Crystallogr.,Sect.D, D67, 2011
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2YIP
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2YIO
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5BIR
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4RNT
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1B2M
 | | THREE-DIMENSIONAL STRUCTURE OF RIBONULCEASE T1 COMPLEXED WITH AN ISOSTERIC PHOSPHONATE ANALOGUE OF GPU: ALTERNATE SUBSTRATE BINDING MODES AND CATALYSIS. | | Descriptor: | 5'-R(*GP*(U34))-3', RIBONUCLEASE T1 | | Authors: | Arni, R.K, Watanabe, L, Ward, R.J, Kreitman, R.J, Kumar, K, Walz Jr, F.G. | | Deposit date: | 1998-11-27 | | Release date: | 1999-03-25 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis.
Biochemistry, 38, 1999
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3BIR
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4BIR
 | | RIBONUCLEASE T1: FREE HIS92GLN MUTANT | | Descriptor: | CALCIUM ION, GUANYL-SPECIFIC RIBONUCLEASE T1 | | Authors: | Doumen, J, Steyaert, J. | | Deposit date: | 1998-01-13 | | Release date: | 1998-07-15 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Role of histidine-40 in ribonuclease T1 catalysis: three-dimensionalstructures of the partially active His40Lys mutant.
Biochemistry, 31, 1992
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6XVT
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-PPPPTEDDL-NH2 | | Descriptor: | ACY-SC1-SC2-SC3-SC4-SC5-NME, NITRATE ION, Protein enabled homolog, ... | | Authors: | Barone, M, Le Cong, K, Roske, Y. | | Deposit date: | 2020-01-22 | | Release date: | 2020-03-18 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6QAY
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7AKI
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-1]-NH2 | | Descriptor: | (3~{S},7~{R},10~{R},13~{S})-4-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-ene-13-carboxamide, NITRATE ION, Protein enabled homolog | | Authors: | Barone, M, Roske, Y. | | Deposit date: | 2020-10-01 | | Release date: | 2020-11-25 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
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1BIR
 | | RIBONUCLEASE T1, PHE 100 TO ALA MUTANT COMPLEXED WITH 2' GMP | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 | | Authors: | Doumen, J, Gonciarz, M, Zegers, I, Loris, R, Wyns, L, Steyaert, J. | | Deposit date: | 1996-01-04 | | Release date: | 1996-08-17 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1.
Protein Sci., 5, 1996
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1RN1
 | | THREE-DIMENSIONAL STRUCTURE OF GLN 25-RIBONUCLEASE T1 AT 1.84 ANGSTROMS RESOLUTION: STRUCTURAL VARIATIONS AT THE BASE RECOGNITION AND CATALYTIC SITES | | Descriptor: | RIBONUCLEASE T1 ISOZYME, SULFATE ION | | Authors: | Arni, R.K, Pal, G.P, Ravichandran, K.G, Tulinsky, A, Walz Junior, F.G, Metcalf, P. | | Deposit date: | 1991-11-22 | | Release date: | 1994-01-31 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Three-dimensional structure of Gln25-ribonuclease T1 at 1.84-A resolution: structural variations at the base recognition and catalytic sites.
Biochemistry, 31, 1992
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8Q1X
 | | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | | Authors: | Roske, Y, Daumke, O, Damme, M. | | Deposit date: | 2023-08-01 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Nucleic Acids Res., 52, 2024
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8Q1K
 | | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | | Authors: | Roske, Y, Daumke, O, Damme, M. | | Deposit date: | 2023-07-31 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Nucleic Acids Res., 52, 2024
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