2M4F
| Solution Structure of Outer surface protein E | Descriptor: | Outer surface protein E | Authors: | Bhattacharjee, A, Oeemig, J.S, Kolodziejczyk, R, Meri, T, Kajander, T, Iwai, H, Jokiranta, T, Goldman, A. | Deposit date: | 2013-02-05 | Release date: | 2013-05-15 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural Basis for Complement Evasion by Lyme Disease Pathogen Borrelia burgdorferi J.Biol.Chem., 288, 2013
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4AV6
| Crystal structure of Thermotoga maritima sodium pumping membrane integral pyrophosphatase at 4 A in complex with phosphate and magnesium | Descriptor: | K(+)-STIMULATED PYROPHOSPHATE-ENERGIZED SODIUM PUMP, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Kajander, T, Kellosalo, J, Kogan, K, Pokharel, K, Goldman, A. | Deposit date: | 2012-05-23 | Release date: | 2012-08-08 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | The Structure and Catalytic Cycle of a Sodium-Pumping Pyrophosphatase. Science, 337, 2012
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4MUC
| The 4th and 5th C-terminal domains of Factor H related protein 1 | Descriptor: | Complement factor H-related protein 1, SULFATE ION | Authors: | Bhattacharjee, A, Goldman, A, Kolodziejczyk, R, Jokiranta, T.S. | Deposit date: | 2013-09-21 | Release date: | 2015-02-18 | Last modified: | 2015-05-06 | Method: | X-RAY DIFFRACTION (2.897 Å) | Cite: | The Major Autoantibody Epitope on Factor H in Atypical Hemolytic Uremic Syndrome Is Structurally Different from Its Homologous Site in Factor H-related Protein 1, Supporting a Novel Model for Induction of Autoimmunity in This Disease. J.Biol.Chem., 290, 2015
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1WPP
| Structure of Streptococcus gordonii inorganic pyrophosphatase | Descriptor: | CHLORIDE ION, Probable manganese-dependent inorganic pyrophosphatase, SULFATE ION, ... | Authors: | Fabrichniy, I.P, Lehtio, L, Salminen, A, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2004-09-09 | Release date: | 2004-11-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Studies of Metal Ions in Family II Pyrophosphatases: The Requirement for a Janus Ion Biochemistry, 43, 2004
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1WPN
| Crystal structure of the N-terminal core of Bacillus subtilis inorganic pyrophosphatase | Descriptor: | MANGANESE (II) ION, Manganese-dependent inorganic pyrophosphatase, SULFATE ION | Authors: | Fabrichniy, I.P, Lehtio, L, Salminen, A, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2004-09-09 | Release date: | 2004-11-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural Studies of Metal Ions in Family II Pyrophosphatases: The Requirement for a Janus Ion Biochemistry, 43, 2004
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1WPM
| Structure of Bacillus subtilis inorganic pyrophosphatase | Descriptor: | Manganese-dependent inorganic pyrophosphatase, SULFATE ION, TETRAETHYLENE GLYCOL | Authors: | Fabrichniy, I.P, Lehtio, L, Salminen, A, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2004-09-09 | Release date: | 2004-11-23 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Studies of Metal Ions in Family II Pyrophosphatases: The Requirement for a Janus Ion Biochemistry, 43, 2004
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6QP4
| Structure of 299-452 fragment of the UspA1 protein from Moraxella catarrhalis | Descriptor: | CHLORIDE ION, HEXANE-1,6-DIOL, UspA1, ... | Authors: | Mikula, K.M, Kolodziejczyk, R, Goldman, A. | Deposit date: | 2019-02-13 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the UspA1 protein fragment from Moraxella catarrhalis responsible for C3d binding. J.Struct.Biol., 208, 2019
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4AV3
| Crystal structure of Thermotoga Maritima sodium pumping membrane integral pyrophosphatase with metal ions in active site | Descriptor: | CALCIUM ION, K(+)-STIMULATED PYROPHOSPHATE-ENERGIZED SODIUM PUMP, MAGNESIUM ION | Authors: | Kajander, T, Kogan, K, Kellosalo, J, Pokharel, K, Goldman, A. | Deposit date: | 2012-05-23 | Release date: | 2012-08-08 | Last modified: | 2018-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Structure and Catalytic Cycle of a Sodium-Pumping Pyrophosphatase. Science, 337, 2012
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4BWC
| X-ray structure of a phospholiapse B like protein 1 from bovine kidneys | Descriptor: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Repo, H, Kuokkanen, E, Oksanen, E, Goldman, A, Heikinheimo, P. | Deposit date: | 2013-07-01 | Release date: | 2013-09-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Is the Bovine Lysosomal Phospholipase B-Like Protein an Amidase? Proteins, 82, 2014
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1F9C
| CRYSTAL STRUCTURE OF MLE D178N VARIANT | Descriptor: | MANGANESE (II) ION, PROTEIN (MUCONATE CYCLOISOMERASE I) | Authors: | Kajander, T, Lehtio, L, Kahn, P.C, Goldman, A. | Deposit date: | 2000-07-10 | Release date: | 2001-03-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Buried charged surface in proteins. Structure Fold.Des., 8, 2000
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1QHM
| ESCHERICHIA COLI PYRUVATE FORMATE LYASE LARGE DOMAIN | Descriptor: | PYRUVATE FORMATE-LYASE | Authors: | Leppanen, V.-M, Merckel, M.C, Ollis, D.L, Wong, K.K, Kozarich, J.W, Goldman, A. | Deposit date: | 1999-05-19 | Release date: | 2000-05-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Pyruvate formate lyase is structurally homologous to type I ribonucleotide reductase. Structure Fold.Des., 7, 1999
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4J38
| Structure of Borrelia burgdorferi Outer surface protein E in complex with Factor H domains 19-20 | Descriptor: | Complement factor H, Outer surface protein E, SULFATE ION | Authors: | Bhattacharjee, A, Kolodziejczyk, R, Kajander, T, Goldman, A, Jokiranta, T.S. | Deposit date: | 2013-02-05 | Release date: | 2013-05-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Structural Basis for Complement Evasion by Lyme Disease Pathogen Borrelia burgdorferi J.Biol.Chem., 288, 2013
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2EIP
| INORGANIC PYROPHOSPHATASE | Descriptor: | SOLUBLE INORGANIC PYROPHOSPHATASE | Authors: | Kankare, J.A, Salminen, T, Goldman, A. | Deposit date: | 1996-01-10 | Release date: | 1996-11-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Escherichia coli inorganic pyrophosphatase at 2.2 A resolution. Acta Crystallogr.,Sect.D, 52, 1996
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3FUB
| Crystal structure of GDNF-GFRalpha1 complex | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Parkash, V, Goldman, A. | Deposit date: | 2009-01-14 | Release date: | 2009-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Comparison of GFL-GFRalpha complexes: further evidence relating GFL bend angle to RET signalling Acta Crystallogr.,Sect.F, 65, 2009
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1HIB
| THE STRUCTURE OF AN INTERLEUKIN-1 BETA MUTANT WITH REDUCED BIOACTIVITY SHOWS MULTIPLE SUBTLE CHANGES IN CONFORMATION THAT AFFECT PROTEIN-PROTEIN RECOGNITION | Descriptor: | INTERLEUKIN-1 BETA | Authors: | Camacho, N.P, Smith, D.R, Goldman, A, Schneider, B, Green, D, Young, P.R, Berman, H.M. | Deposit date: | 1993-03-29 | Release date: | 1994-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of an interleukin-1 beta mutant with reduced bioactivity shows multiple subtle changes in conformation that affect protein-protein recognition. Biochemistry, 32, 1993
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5LNL
| Crystal structure of Hsf 1608-1749 putative domain 1 | Descriptor: | Hsf | Authors: | Thomsen, M, Wright, J, Ridley, J, Goldman, A. | Deposit date: | 2016-08-05 | Release date: | 2017-02-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The crystal structure of PD1, a Haemophilus surface fibril domain. Acta Crystallogr F Struct Biol Commun, 73, 2017
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5LZR
| Crystal structure of Thermotoga maritima sodium pumping membrane integral pyrophosphatase in complex with tungstate and magnesium | Descriptor: | K(+)-stimulated pyrophosphate-energized sodium pump, MAGNESIUM ION, TUNGSTATE(VI)ION | Authors: | Wilkinson, C, Kellosalo, J, Kajander, T, Goldman, A. | Deposit date: | 2016-10-01 | Release date: | 2016-12-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism. Nat Commun, 7, 2016
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1E6A
| Fluoride-inhibited substrate complex of Saccharomyces cerevisiae inorganic pyrophosphatase | Descriptor: | FLUORIDE ION, INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, ... | Authors: | Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2000-08-09 | Release date: | 2001-03-19 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase. Proc. Natl. Acad. Sci. U.S.A., 98, 2001
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5LZQ
| Crystal structure of Thermotoga maritima sodium pumping membrane integral pyrophosphatase in complex with imidodiphosphate and magnesium, and with bound sodium ion | Descriptor: | IMIDODIPHOSPHORIC ACID, K(+)-stimulated pyrophosphate-energized sodium pump, MAGNESIUM ION, ... | Authors: | Wilkinson, C, Kellosalo, J, Kajander, T, Goldman, A. | Deposit date: | 2016-10-01 | Release date: | 2016-12-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.495 Å) | Cite: | Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism. Nat Commun, 7, 2016
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5ML9
| Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer F4, a specific binding protein which blocks IgG binding to the receptor. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer F4 with specificity for Fc gamma receptor IIIa, CHLORIDE ION, ... | Authors: | Robinson, J.I, Tomlinson, D.C, Baxter, E.W, Owen, R.L, Thomsen, M, Win, S.J, Nettleship, J.E, Tiede, C, Foster, R.J, Waterhouse, M.P, Harris, S.A, Owens, R.J, Fishwick, C.W.G, Goldman, A, McPherson, M.J, Morgan, A.W. | Deposit date: | 2016-12-06 | Release date: | 2017-12-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5MN2
| Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer G3, a specific binding protein which blocks IgG binding to the receptor. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer G3, DI(HYDROXYETHYL)ETHER, ... | Authors: | Robinson, J.I, Owen, R.L, Tomlinson, D.C, Baxter, E.W, Nettleship, J.E, Waterhouse, M.P, Harris, S.A, Owens, R.J, McPherson, M.J, Morgan, A.W, Tiede, C, Goldman, A, Thomsen, M. | Deposit date: | 2016-12-12 | Release date: | 2017-12-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1E9G
| STRUCTURE OF INORGANIC PYROPHOSPHATASE | Descriptor: | INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PHOSPHATE ION | Authors: | Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2000-10-12 | Release date: | 2001-03-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Toward a Quantum-Mechanical Description of Metal-Assisted Phosphoryl Transfer in Pyrophosphatase Proc.Natl.Acad.Sci.USA, 98, 2001
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2XQW
| Structure of Factor H domains 19-20 in complex with complement C3d | Descriptor: | COMPLEMENT C3, COMPLEMENT FACTOR H | Authors: | Kajander, T, Lehtinen, M.J, Hyvarinen, S, Bhattacharjee, A, Leung, E, Isenman, D.E, Meri, S, Jokiranta, T.S, Goldman, A. | Deposit date: | 2010-09-07 | Release date: | 2011-02-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.306 Å) | Cite: | Dual Interaction of Factor H with C3D and Glycosaminoglycans in Host-Nonhost Discrimination by Complement. Proc.Natl.Acad.Sci.USA, 108, 2011
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1Q8D
| The crystal structure of GDNF family co-receptor alpha 1 domain 3 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GDNF family receptor alpha 1 | Authors: | Leppanen, V.M, Bespalov, M.M, Runeberg-Roos, P, Puurand, U, Merits, A, Saarma, M, Goldman, A. | Deposit date: | 2003-08-21 | Release date: | 2004-08-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation. Embo J., 23, 2004
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2PK0
| Structure of the S. agalactiae serine/threonine phosphatase at 2.65 resolution | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Rantanen, M.K, Lehtio, L, Rajagopal, L, Rubens, C.E, Goldman, A. | Deposit date: | 2007-04-17 | Release date: | 2007-06-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of Streptococcus agalactiae serine/threonine phosphatase. The subdomain conformation is coupled to the binding of a third metal ion Febs J., 274, 2007
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