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4ONL
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BU of 4onl by Molmil
Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ORH
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BU of 4orh by Molmil
Crystal structure of RNF8 bound to the UBC13/MMS2 heterodimer
Descriptor: E3 ubiquitin-protein ligase RNF8, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-02-11
Release date:2014-02-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.802 Å)
Cite:Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012
4OFB
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BU of 4ofb by Molmil
Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
Descriptor: Breast cancer type 1 susceptibility protein, nonphosphopeptide inhibitor
Authors:Sun, L, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-14
Release date:2015-04-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain.
Acs Chem.Biol., 10, 2015
4ONN
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BU of 4onn by Molmil
Crystal structure of human Mms2/Ubc13 - BAY 11-7082
Descriptor: 3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4QPQ
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BU of 4qpq by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
Descriptor: Relaxosome protein TraM, sbmA DNA1, sbmA DNA2
Authors:Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
Deposit date:2014-06-24
Release date:2014-09-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
4QPO
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BU of 4qpo by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
Descriptor: PHOSPHATE ION, Relaxosome protein TraM
Authors:Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
Deposit date:2014-06-24
Release date:2014-09-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
1JNX
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BU of 1jnx by Molmil
Crystal structure of the BRCT repeat region from the breast cancer associated protein, BRCA1
Descriptor: BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, NICKEL (II) ION
Authors:Williams, R.S, Green, R, Glover, J.N.M.
Deposit date:2001-07-26
Release date:2001-09-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1.
Nat.Struct.Biol., 8, 2001
1J74
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BU of 1j74 by Molmil
Crystal Structure of Mms2
Descriptor: MMS2
Authors:Moraes, T.F, Edwards, R.A, McKenna, S, Pastushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
Deposit date:2001-05-15
Release date:2001-08-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
1J7D
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BU of 1j7d by Molmil
Crystal Structure of hMms2-hUbc13
Descriptor: MMS2, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA
Authors:Moraes, T.F, Edwards, R.A, McKenna, S, Pashushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
Deposit date:2001-05-16
Release date:2001-08-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
1A02
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BU of 1a02 by Molmil
STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA
Descriptor: AP-1 FRAGMENT FOS, AP-1 FRAGMENT JUN, DNA (5'-D(*DAP*DAP*DCP*DTP*DAP*DTP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DTP*DTP*DTP*DTP*DCP*DC)-3'), ...
Authors:Chen, L, Glover, J.N.M, Hogan, P.G, Rao, A, Harrison, S.C.
Deposit date:1997-12-08
Release date:1998-05-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.
Nature, 392, 1998
2R1Z
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BU of 2r1z by Molmil
Crystal Structure of the BARD1 BRCT Repeat
Descriptor: BRCA1-associated RING domain protein 1, GLYCEROL
Authors:Lee, M.S, Edwards, R.A, Williams, R.S, Glover, M.J.N.
Deposit date:2007-08-23
Release date:2007-09-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the BARD1 BRCT Repeat
To be Published
7RGT
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BU of 7rgt by Molmil
The crystal structure of RocC, containing FinO domain, 1-126
Descriptor: Repressor of competence, RNA Chaperone, SULFATE ION
Authors:Kim, H.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2021-07-15
Release date:2022-11-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones.
Nat Commun, 13, 2022
7RGS
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BU of 7rgs by Molmil
The crystal structure of RocC, containing FinO domain, 24-126
Descriptor: Repressor of competence, RNA Chaperone
Authors:Kim, H.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2021-07-15
Release date:2022-11-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones.
Nat Commun, 13, 2022
7RGU
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BU of 7rgu by Molmil
The crystal structure of RocC bound to a transcriptional terminator
Descriptor: Modified SL3 of RocR, Repressor of competence, RNA Chaperone
Authors:Kim, H.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2021-07-15
Release date:2022-11-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones.
Nat Commun, 13, 2022
4KQD
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BU of 4kqd by Molmil
The crystal Structure of the N-terminal PAS domain of the F plasmid TraJ
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DITHIANE DIOL, GLYCEROL, ...
Authors:Lu, J, Glover, J.N.M.
Deposit date:2013-05-14
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The crystal Structure of the N-terminal PAS domain of the F plasmid TraJ
To be Published
1T2U
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BU of 1t2u by Molmil
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F
Descriptor: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M.
Deposit date:2004-04-22
Release date:2004-05-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
1T2V
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BU of 1t2v by Molmil
Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide
Descriptor: BRCTide-7PS, Breast cancer type 1 susceptibility protein
Authors:Williams, R.S, Lee, M.S, Hau, D.D, Glover, J.N.M.
Deposit date:2004-04-22
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
2F9D
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BU of 2f9d by Molmil
2.5 angstrom resolution structure of the spliceosomal protein p14 bound to region of SF3b155
Descriptor: Pre-mRNA branch site protein p14, Splicing factor 3B subunit 1
Authors:Schellenberg, M.J, Edwards, R.A, Ritchie, D.B, Glover, J.N.M, Macmillan, A.M.
Deposit date:2005-12-05
Release date:2006-01-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a core spliceosomal protein interface
Proc.Natl.Acad.Sci.Usa, 103, 2006
8D34
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BU of 8d34 by Molmil
Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A
Descriptor: Uridylate-specific endoribonuclease nsp15
Authors:Farraj, R.A, Edwards, R.A, Glover, J.N.M.
Deposit date:2022-05-31
Release date:2023-06-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A
To Be Published
1MN4
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BU of 1mn4 by Molmil
Structure of Ndt80 (Residues 59-340) DNA-binding domain core
Descriptor: NDT80 PROTEIN
Authors:Lamoureux, J.S, Stuart, D, Tsang, R, Wu, C, Glover, J.N.M.
Deposit date:2002-09-04
Release date:2002-11-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the sporulation-specific transcription factor Ndt80 bound to DNA
Embo J., 21, 2002
1N5O
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BU of 1n5o by Molmil
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
Descriptor: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
Authors:Williams, R.S, Glover, J.N.M.
Deposit date:2002-11-06
Release date:2002-12-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
J.Biol.Chem., 278, 2003
3MW6
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BU of 3mw6 by Molmil
Crystal structure of NMB1681 from Neisseria meningitidis MC58, a FinO-like RNA chaperone
Descriptor: GLYCEROL, uncharacterized protein NMB1681
Authors:Tan, K, Zhou, M, Duggan, E, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-05-05
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.209 Å)
Cite:N. meningitidis 1681 is a member of the FinO family of RNA chaperones.
Rna Biol., 7, 2010
3HUE
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BU of 3hue by Molmil
Structure of the S. pombe Nbs1 FHA-BRCT1-BRCT2 domains
Descriptor: DNA repair and telomere maintenance protein nbs1
Authors:Williams, R.S, Guenther, G, Tainer, J.A.
Deposit date:2009-06-13
Release date:2009-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Cell(Cambridge,Mass.), 139, 2009
3HUF
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BU of 3huf by Molmil
Structure of the S. pombe Nbs1-Ctp1 complex
Descriptor: DNA repair and telomere maintenance protein nbs1, Double-strand break repair protein ctp1, THIOCYANATE ION
Authors:Williams, R.S, Guenther, G, Tainer, J.A.
Deposit date:2009-06-13
Release date:2009-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.
Cell(Cambridge,Mass.), 139, 2009
3L11
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BU of 3l11 by Molmil
Crystal Structure of the Ring Domain of RNF168
Descriptor: E3 ubiquitin-protein ligase RNF168, MALONATE ION, ZINC ION
Authors:Neculai, D, Yermekbayeva, L, Crombet, L, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-12-10
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012

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