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5A7B
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BU of 5a7b by Molmil
Structure of the p53 cancer Y220C bound to the stabilizing small molecule PhiKan5211
Descriptor: 2-[[4-(diethylamino)piperidin-1-yl]methyl]-6-ethynyl-4-(3-phenoxyprop-1-ynyl)phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C.
Deposit date:2015-07-03
Release date:2015-09-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen Bioisostere.
Acs Chem.Biol., 10, 2015
5AB9
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BU of 5ab9 by Molmil
Structure of the p53 cancer mutant Y220C with bound small molecule 7- ethyl-3-(piperidin-4-yl)-1H-indole
Descriptor: 7-ethyl-3-(piperidin-4-yl)-1H-indole, CELLULAR TUMOR ANTIGEN P53, DI(HYDROXYETHYL)ETHER, ...
Authors:Joerger, A.C.
Deposit date:2015-08-04
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53.
Structure, 23, 2015
5ABA
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BU of 5aba by Molmil
Structure of the p53 cancer mutant Y220C with bound small-molecule stabilizer PhiKan5149
Descriptor: 1-{1-[(3-bromo-5-chloro-2-hydroxyphenyl)methyl piperidin-4-yl}piperidin-4-ol], CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C.
Deposit date:2015-08-04
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53.
Structure, 23, 2015
1BNS
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BU of 1bns by Molmil
STRUCTURAL STUDIES OF BARNASE MUTANTS
Descriptor: BARNASE
Authors:Chen, Y.W.
Deposit date:1994-04-11
Release date:1994-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Contribution of buried hydrogen bonds to protein stability. The crystal structures of two barnase mutants.
J.Mol.Biol., 234, 1993
5AOI
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BU of 5aoi by Molmil
Structure of the p53 cancer mutant Y220C in complex with an indole- based small molecule
Descriptor: 2-(5-BROMO-7-ETHYL-2-METHYL-1H-INDOLE-3-YL)ETHAN-1-AMIN, CELLULAR TUMOR ANTIGEN P53, DI(HYDROXYETHYL)ETHER, ...
Authors:Joerger, A.C, Wilcken, R.
Deposit date:2015-09-10
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53.
Structure, 23, 2015
5AOM
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BU of 5aom by Molmil
Structure of the p53 cancer mutant Y220C with bound small molecule PhiKan883
Descriptor: CELLULAR TUMOR ANTIGEN P53, GLYCEROL, N-(5-chloranyl-2-oxidanyl-phenyl)piperidine-4-carboxamide, ...
Authors:Joerger, A.C, Boeckler, F.M, Wilcken, R.
Deposit date:2015-09-10
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53.
Structure, 23, 2015
5AOL
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BU of 5aol by Molmil
Structure of the p53 cancer mutant Y220C with bound 3-bromo-5-(trifluoromethyl)benzene-1,2-diamine
Descriptor: 3-BROMO-5-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE, CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C, Harbrecht, H.
Deposit date:2015-09-10
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53.
Structure, 23, 2015
5AOK
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BU of 5aok by Molmil
Structure of the p53 cancer mutant Y220C with bound small molecule PhiKan7099
Descriptor: 5-[2-cyclopropyl-5-(1H-pyrrol-1-yl)-1,3-oxazol-4-yl]-1H-1,2,3,4-tetrazole, CELLULAR TUMOR ANTIGEN P53, DI(HYDROXYETHYL)ETHER, ...
Authors:Joerger, A.C.
Deposit date:2015-09-10
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53.
Structure, 23, 2015
1UQS
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BU of 1uqs by Molmil
The Crystal Structure of Human CD1b with a Bound Bacterial Glycolipid
Descriptor: BETA-2-MICROGLOBULIN, GLUCOSE MONOMYCOLATE, T-CELL SURFACE GLYCOPROTEIN CD1B
Authors:Batuwangala, T, Shepherd, D, Gadola, S.D, Gibson, K.J.C, Zaccai, N.R, Besra, G.S, Cerundolo, V, Jones, E.Y.
Deposit date:2003-10-16
Release date:2003-10-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The crystal structure of human CD1b with a bound bacterial glycolipid.
J Immunol., 172, 2004
1BRI
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BU of 1bri by Molmil
BARNASE MUTANT WITH ILE 76 REPLACED BY ALA
Descriptor: BARNASE
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1BRH
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BU of 1brh by Molmil
BARNASE MUTANT WITH LEU 14 REPLACED BY ALA
Descriptor: BARNASE, ZINC ION
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1BRK
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BU of 1brk by Molmil
BARNASE MUTANT WITH ILE 96 REPLACED BY ALA
Descriptor: BARNASE, ZINC ION
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
1BRJ
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BU of 1brj by Molmil
BARNASE MUTANT WITH ILE 88 REPLACED BY ALA
Descriptor: BARNASE, ZINC ION
Authors:Cramer, P.C, Buckle, A, Fersht, A.
Deposit date:1995-03-09
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
2P81
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BU of 2p81 by Molmil
Engrailed homeodomain helix-turn-helix motif
Descriptor: Segmentation polarity homeobox protein engrailed
Authors:Religa, T.L.
Deposit date:2007-03-21
Release date:2007-06-12
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:The helix-turn-helix motif as an ultrafast independently folding domain: The pathway of folding of Engrailed homeodomain.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2WQJ
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BU of 2wqj by Molmil
Crystal structure of a truncated variant of the human p73 tetramerization domain
Descriptor: TUMOR PROTEIN P73
Authors:Joerger, A.C.
Deposit date:2009-08-21
Release date:2009-10-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WQI
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BU of 2wqi by Molmil
Crystal structure of the human p73 tetramerization domain
Descriptor: TUMOR PROTEIN P73
Authors:Joerger, A.C.
Deposit date:2009-08-21
Release date:2009-10-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WTT
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BU of 2wtt by Molmil
Structure of the human p73 tetramerization domain (crystal form II)
Descriptor: TUMOR PROTEIN P73
Authors:Joerger, A.C.
Deposit date:2009-09-21
Release date:2009-10-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
Proc.Natl.Acad.Sci.USA, 106, 2009
4TS1
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BU of 4ts1 by Molmil
CRYSTAL STRUCTURE OF A DELETION MUTANT OF A TYROSYL-T/RNA SYNTHETASE COMPLEXED WITH TYROSINE
Descriptor: TYROSINE, TYROSYL-tRNA SYNTHETASE
Authors:Brick, P, Blow, D.M.
Deposit date:1989-06-29
Release date:1989-10-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a deletion mutant of a tyrosyl-tRNA synthetase complexed with tyrosine.
J.Mol.Biol., 194, 1987
1BNR
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BU of 1bnr by Molmil
BARNASE
Descriptor: BARNASE (G SPECIFIC ENDONUCLEASE)
Authors:Bycroft, M.
Deposit date:1995-03-31
Release date:1995-07-31
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Determination of the three-dimensional solution structure of barnase using nuclear magnetic resonance spectroscopy.
Biochemistry, 30, 1991
1CQ4
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BU of 1cq4 by Molmil
CI2 MUTANT WITH TETRAGLUTAMINE (MGQQQQGM) REPLACING MET59
Descriptor: PROTEIN (SERINE PROTEINASE INHIBITOR 2), SULFATE ION
Authors:Chen, Y.W, Stott, K.R.
Deposit date:1998-11-17
Release date:1998-11-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a dimeric chymotrypsin inhibitor 2 mutant containing an inserted glutamine repeat.
Proc.Natl.Acad.Sci.USA, 96, 1999
1SRV
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BU of 1srv by Molmil
THERMUS THERMOPHILUS GROEL (HSP60 CLASS) FRAGMENT (APICAL DOMAIN) COMPRISING RESIDUES 192-336
Descriptor: PROTEIN (GROEL (HSP60 CLASS))
Authors:Walsh, M.A, Dementieva, I, Evans, G, Sanishvili, R, Joachimiak, A.
Deposit date:1999-03-02
Release date:1999-03-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Taking MAD to the extreme: ultrafast protein structure determination.
Acta Crystallogr.,Sect.D, 55, 1999
1TYP
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BU of 1typ by Molmil
SUBSTRATE INTERACTIONS BETWEEN TRYPANOTHIONE REDUCTASE AND N1-GLUTATHIONYLSPERMIDINE DISULPHIDE AT 0.28-NM RESOLUTION
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Bailey, S, Hunter, W.N.
Deposit date:1992-06-29
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Substrate interactions between trypanothione reductase and N1-glutathionylspermidine disulphide at 0.28-nm resolution.
Eur.J.Biochem., 213, 1993

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