7S1N
 
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4KFW
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4KFV
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8H3I
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8H3J
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7Y67
 | | Cryo-EM structure of C089-bound C5aR1(I116A) mutant in complex with Gi protein | | 分子名称: | C089 peptide, C5a anaphylatoxin chemotactic receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Feng, Y.Y, Zhao, C, Yan, W, Shao, Z.H. | | 登録日 | 2022-06-18 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Mechanism of activation and biased signaling in complement receptor C5aR1.
Cell Res., 33, 2023
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7Y64
 | | Cryo-EM structure of C5a-bound C5aR1 in complex with Gi protein | | 分子名称: | C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Feng, Y.Y, Zhao, C, Yan, W, Shao, Z.H. | | 登録日 | 2022-06-18 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Mechanism of activation and biased signaling in complement receptor C5aR1.
Cell Res., 33, 2023
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7Y65
 | | Cryo-EM structure of C5a peptide-bound C5aR1 in complex with Gi protein | | 分子名称: | C5a anaphylatoxin chemotactic receptor 1, C5apep peptide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Feng, Y.Y, Zhao, C, Yan, W, Shao, Z.H. | | 登録日 | 2022-06-18 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of activation and biased signaling in complement receptor C5aR1.
Cell Res., 33, 2023
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7Y66
 | | Cryo-EM structure of BM213-bound C5aR1 in complex with Gi protein | | 分子名称: | BM213 peptide, C5a anaphylatoxin chemotactic receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Feng, Y.Y, Zhao, C, Yan, W, Shao, Z.H. | | 登録日 | 2022-06-18 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-04-19 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Mechanism of activation and biased signaling in complement receptor C5aR1.
Cell Res., 33, 2023
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6JX1
 | | Crystal structure of Formate dehydrogenase mutant V198I/C256I/P260S/E261P/S381N/S383F from Pseudomonas sp. 101 | | 分子名称: | Formate dehydrogenase, GLYCEROL | | 著者 | Feng, Y, Xue, S, Guo, X, Zhao, Z. | | 登録日 | 2019-04-21 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.233 Å) | | 主引用文献 | Structure-Guided Design of Formate Dehydrogenase for Regeneration of a Non-Natural Redox Cofactor.
Chemistry, 26, 2020
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6JUK
 | | Crystal structure of Formate dehydrogenase mutant C256I/E261P/S381I from Pseudomonas sp. 101 in complex with non-natural cofactor Nicotinamide Cytosine Dinucleotide | | 分子名称: | Formate dehydrogenase, GLYCEROL, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Feng, Y, Xue, S, Guo, X, Zhao, Z. | | 登録日 | 2019-04-14 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.293 Å) | | 主引用文献 | Structure-Guided Design of Formate Dehydrogenase for Regeneration of a Non-Natural Redox Cofactor.
Chemistry, 26, 2020
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6JWG
 | | Crystal structure of Formate dehydrogenase mutant C256I/E261P/S381I from Pseudomonas sp. 101 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Formate dehydrogenase, GLYCEROL | | 著者 | Feng, Y, Guo, X, Xue, S, Zhao, Z. | | 登録日 | 2019-04-20 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.081 Å) | | 主引用文献 | Structure-Guided Design of Formate Dehydrogenase for Regeneration of a Non-Natural Redox Cofactor.
Chemistry, 26, 2020
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6N82
 | | Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02037 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Farnesyl pyrophosphate synthase, ... | | 著者 | Park, J, Schilling, M.A, Berghuis, A.M. | | 登録日 | 2018-11-28 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Chirality-Driven Mode of Binding of alpha-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS).
J.Med.Chem., 62, 2019
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6N7Y
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6N83
 | | Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02037 | | 分子名称: | CHLORIDE ION, Farnesyl pyrophosphate synthase, PHOSPHATE ION, ... | | 著者 | Park, J, Schilling, M.A, Berghuis, A.M. | | 登録日 | 2018-11-28 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Chirality-Driven Mode of Binding of alpha-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS).
J.Med.Chem., 62, 2019
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6N7Z
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6OAH
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6JUJ
 | | Crystal structure of Formate dehydrogenase mutant V198I/C256I/P260S/E261P/S381N/S383F from Pseudomonas sp. 101in complex with non-natural cofactor Nicotinamide Cytosine Dinucleotide | | 分子名称: | Formate dehydrogenase, GLYCEROL, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Feng, Y, Guo, X, Xue, S, Zhao, Z. | | 登録日 | 2019-04-14 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.183 Å) | | 主引用文献 | Structure-Guided Design of Formate Dehydrogenase for Regeneration of a Non-Natural Redox Cofactor.
Chemistry, 26, 2020
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7WIN
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8GB8
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8GB7
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8GB6
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8GB5
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody 25F9 | | 分子名称: | 25F9 Heavy chain, 25F9 Light chain, BICINE, ... | | 著者 | Yuan, M, Zhu, X, Wilson, I.A. | | 登録日 | 2023-02-24 | | 公開日 | 2023-05-24 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Sci Transl Med, 15, 2023
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7O52
 | | CD22 d6-d7 in complex with Fab m971 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD22 d6-d7 Ig domains, GLYCEROL, ... | | 著者 | Ereno-Orbea, J, Sicard, T, Julien, J.P. | | 登録日 | 2021-04-07 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22.
J.Biol.Chem., 297, 2021
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7O4Y
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