8GB5
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody 25F9
Summary for 8GB5
Entry DOI | 10.2210/pdb8gb5/pdb |
Descriptor | Spike protein S1, 25F9 Heavy chain, 25F9 Light chain, ... (10 entities in total) |
Functional Keywords | covid-19, sars-cov-2, antibody, spike, receptor binding domain, immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 12 |
Total formula weight | 286984.43 |
Authors | |
Primary citation | Feng, Y.,Yuan, M.,Powers, J.M.,Hu, M.,Munt, J.E.,Arunachalam, P.S.,Leist, S.R.,Bellusci, L.,Kim, J.,Sprouse, K.R.,Adams, L.E.,Sundaramurthy, S.,Zhu, X.,Shirreff, L.M.,Mallory, M.L.,Scobey, T.D.,Moreno, A.,O'Hagan, D.T.,Kleanthous, H.,Villinger, F.J.,Veesler, D.,King, N.P.,Suthar, M.S.,Khurana, S.,Baric, R.S.,Wilson, I.A.,Pulendran, B. Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine. Sci Transl Med, 15:eadg7404-eadg7404, 2023 Cited by PubMed: 37163615DOI: 10.1126/scitranslmed.adg7404 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.35 Å) |
Structure validation
Download full validation report