6JUJ

Crystal structure of Formate dehydrogenase mutant V198I/C256I/P260S/E261P/S381N/S383F from Pseudomonas sp. 101in complex with non-natural cofactor Nicotinamide Cytosine Dinucleotide

Summary for 6JUJ

• Entry DOI: 10.2210/pdb6juj/pdb
• Descriptor: Formate dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate, GLYCEROL, ... (4 entities in total)
• Functional Keywords: formate dehydrogenase, oxidoreductase
• Biological source: Pseudomonas sp. 101 (Achromobacter parvulus T1)
• Total number of polymer chains: 2
• Total formula weight: 90267.72

Authors

Feng, Y.,Guo, X.,Xue, S.,Zhao, Z. (deposition date: 2019-04-14, release date: 2020-05-13, Last modification date: 2023-11-22)

• Primary citation: Guo, X.,Wang, X.,Liu, Y.,Li, Q.,Wang, J.,Liu, W.,Zhao, Z.K.; Structure-Guided Design of Formate Dehydrogenase for Regeneration of a Non-Natural Redox Cofactor.; Chemistry, 26:16611-16615, 2020; PubMed: 32815230; DOI: 10.1002/chem.202003102

Experimental method

X-RAY DIFFRACTION (2.183 Å)