7WG8
 
 | | Delta Spike Trimer(3 RBD Down) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Cui, Z. | | 登録日 | 2021-12-28 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron.
Cell, 185, 2022
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7WG9
 | | Delta Spike Trimer(1 RBD Up) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Cui, Z. | | 登録日 | 2021-12-28 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron.
Cell, 185, 2022
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7X9Q
 | | Crystal structure of human STING complexed with compound BSP16 | | 分子名称: | (2R)-4-(5,6-dimethoxy-1-benzoselenophen-2-yl)-2-ethyl-4-oxidanylidene-butanoic acid, Stimulator of interferon genes protein | | 著者 | Pan, L, Guan, X, Feng, X, Li, Z, Bian, J. | | 登録日 | 2022-03-15 | | 公開日 | 2022-09-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Discovery of Selenium-Containing STING Agonists as Orally Available Antitumor Agents.
J.Med.Chem., 65, 2022
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7X9P
 | | Crystal structure of human STING complexed with compound BSP17 | | 分子名称: | 4-[6-methoxy-5-[3-[[6-methoxy-2-(4-oxidanyl-4-oxidanylidene-butanoyl)-1-benzoselenophen-5-yl]oxy]propoxy]-1-benzoselenophen-2-yl]-4-oxidanylidene-butanoic acid, Stimulator of interferon genes protein | | 著者 | Pan, L, Guan, X, Feng, X, Li, Z, Bian, J. | | 登録日 | 2022-03-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery of Selenium-containing STING agonists as orally available anti tumor agents
To be published
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3CX4
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6RNW
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6RNV
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3QAU
 | | 3-Hydroxy-3-MethylGlutaryl-Coenzyme A Reductase from Streptococcus pneumoniae | | 分子名称: | 3-hydroxy-3-methylglutaryl-coenzyme a reductase, GLYCEROL, SODIUM ION, ... | | 著者 | Zhang, L, Feng, L, Zhou, L, Gui, J, Wan, J. | | 登録日 | 2011-01-11 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | 3-Hydroxy-3-MethylGlutaryl-Coenzyme A Reductase from Streptococcus pneumoniae
To be Published
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3QAE
 | | 3-hydroxy-3-methylglutaryl-coenzyme A reductase of Streptococcus pneumoniae | | 分子名称: | 3-hydroxy-3-methylglutaryl-coenzyme a reductase, CITRIC ACID, GLYCEROL, ... | | 著者 | Zhang, L, Feng, L, Zhou, L, Gui, J, Wan, J. | | 登録日 | 2011-01-10 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase of Streptococcus pneumoniae
To be Published
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6VBK
 | | Crystal structure of N-terminal domain of Mycobacterium tuberculosis complex Lon protease | | 分子名称: | GLYCEROL, Lon211 | | 著者 | Bi, F.K, Chen, C, Chen, X.Y, Guo, C.Y, Lin, D.H. | | 登録日 | 2019-12-19 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the N domain of Lon protease from Mycobacterium avium complex.
Protein Sci., 28, 2019
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6LQN
 | | EBV tegument protein BBRF2 | | 分子名称: | Cytoplasmic envelopment protein 1, NITRATE ION, SULFATE ION | | 著者 | He, H.P, Luo, M, Cao, Y.L, Gao, S. | | 登録日 | 2020-01-14 | | 公開日 | 2020-10-07 | | 最終更新日 | 2021-04-21 | | 実験手法 | X-RAY DIFFRACTION (1.600022 Å) | | 主引用文献 | Structure of Epstein-Barr virus tegument protein complex BBRF2-BSRF1 reveals its potential role in viral envelopment.
Nat Commun, 11, 2020
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6LQO
 | | EBV tegument protein BBRF2/BSRF1 complex | | 分子名称: | ACETATE ION, Cytoplasmic envelopment protein 1, GLYCEROL, ... | | 著者 | He, H.P, Luo, M, Cao, Y.L, Gao, S. | | 登録日 | 2020-01-14 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.0911262 Å) | | 主引用文献 | Structure of Epstein-Barr virus tegument protein complex BBRF2-BSRF1 reveals its potential role in viral envelopment.
Nat Commun, 11, 2020
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2M16
 | | P75/LEDGF PWWP Domain | | 分子名称: | PC4 and SFRS1-interacting protein | | 著者 | Crowe, B.L, Foster, M.P. | | 登録日 | 2012-11-18 | | 公開日 | 2013-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for high-affinity binding of LEDGF PWWP to mononucleosomes.
Nucleic Acids Res., 41, 2013
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4QNC
 | | Crystal structure of a SemiSWEET in an occluded state | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PENTADECANE, chemical transport protein | | 著者 | Yan, X, Yuyong, T, Liang, F, Perry, K. | | 登録日 | 2014-06-17 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.388 Å) | | 主引用文献 | Structures of bacterial homologues of SWEET transporters in two distinct conformations.
Nature, 515, 2014
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6IHG
 | | N terminal domain of Mycobacterium avium complex Lon protease | | 分子名称: | Lon protease | | 著者 | Chen, X.Y, Zhang, S.J, Bi, F.K, Guo, C.Y, Yao, H.W, Lin, D.H. | | 登録日 | 2018-09-29 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | | 主引用文献 | Crystal structure of the N domain of Lon protease from Mycobacterium avium complex.
Protein Sci., 28, 2019
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4QND
 | | Crystal structure of a SemiSWEET | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Chemical transport protein, ... | | 著者 | Yan, X, Yuyong, T, Liang, F, Perry, K. | | 登録日 | 2014-06-17 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Structures of bacterial homologues of SWEET transporters in two distinct conformations.
Nature, 515, 2014
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4RLP
 | | Human p70s6k1 with ruthenium-based inhibitor FL772 | | 分子名称: | CHLORIDE ION, [(amino-kappaN)methanethiolato](3-fluoro-9-methoxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dionato-kappa~2~N,N')(N-methyl-1,4,7-trithiecan-9-amine-kappa~3~S~1~,S~4~,S~7~)ruthenium, p70S6K1 | | 著者 | Domsic, J.F, Barber-Rotenberg, J, Salami, J, Qin, J, Marmorstein, R. | | 登録日 | 2014-10-17 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Development of Organometallic S6K1 Inhibitors.
J.Med.Chem., 58, 2015
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4RLO
 | | Human p70s6k1 with ruthenium-based inhibitor EM5 | | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Domsic, J.F, Barber-Rotenberg, J, Salami, J, Qin, J, Marmorstein, R. | | 登録日 | 2014-10-17 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.527 Å) | | 主引用文献 | Development of Organometallic S6K1 Inhibitors.
J.Med.Chem., 58, 2015
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5XXY
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5Y8V
 | | Crystal structure of GAS41 | | 分子名称: | MAGNESIUM ION, YEATS domain-containing protein 4 | | 著者 | Wang, Y, Hao, Q. | | 登録日 | 2017-08-21 | | 公開日 | 2018-04-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Identification of the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5YJ5
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5YJ4
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1QFD
 | | NMR SOLUTION STRUCTURE OF ALPHA-AMYLASE INHIBITOR (AAI) | | 分子名称: | PROTEIN (ALPHA-AMYLASE INHIBITOR) | | 著者 | Lu, S, Deng, P, Liu, X, Luo, J, Han, R, Gu, X, Liang, S, Wang, X, Feng, L, Lozanov, V, Patthy, A, Pongor, S. | | 登録日 | 1999-04-08 | | 公開日 | 1999-07-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the major alpha-amylase inhibitor of the crop plant amaranth.
J.Biol.Chem., 274, 1999
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7VH8
 | | Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332 | | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase, DIMETHYL SULFOXIDE | | 著者 | Zhao, Y, Zhang, Q, Yang, H, Rao, Z. | | 登録日 | 2021-09-21 | | 公開日 | 2021-11-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332.
Protein Cell, 13, 2022
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7VAH
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